Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maribel Espitia"'
Autor:
Yiu Huen Tsang, Turgut Dogruluk, Philip M. Tedeschi, Joanna Wardwell-Ozgo, Hengyu Lu, Maribel Espitia, Nikitha Nair, Rosalba Minelli, Zechen Chong, Fengju Chen, Qing Edward Chang, Jennifer B. Dennison, Armel Dogruluk, Min Li, Haoqiang Ying, Joseph R. Bertino, Marie-Claude Gingras, Michael Ittmann, John Kerrigan, Ken Chen, Chad J. Creighton, Karina Eterovic, Gordon B. Mills, Kenneth L. Scott
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequent
Externí odkaz:
https://doaj.org/article/ad00a3ec62c944099c564237f8e7c498
Autor:
Kenneth L. Scott, Gordon B. Mills, Ken Chen, Chad J. Creighton, Penelope E. Bonnen, Agna Karina Eterovic, Armel Dogruluk, Vivek Appadurai, Zechen Chong, Tenghui Chen, Fengju Chen, Maribel Espitia, Yiu Huen Tsang, Turgut Dogruluk
PIK3CA mutations in breast cancer from the COSMIC database (S1); Predictions by computational algorithms on the consequences of PIK3CA missense mutations (S2); Mutagenic primer and barcode sequences of PIK3CA constructs and HiTMMoB reaction efficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031a84c258dd582307ad02e2b443320a
https://doi.org/10.1158/0008-5472.22406975.v1
https://doi.org/10.1158/0008-5472.22406975.v1
Autor:
Kenneth L. Scott, Gordon B. Mills, Ken Chen, Chad J. Creighton, Penelope E. Bonnen, Agna Karina Eterovic, Armel Dogruluk, Vivek Appadurai, Zechen Chong, Tenghui Chen, Fengju Chen, Maribel Espitia, Yiu Huen Tsang, Turgut Dogruluk
Large-scale sequencing efforts are uncovering the complexity of cancer genomes, which are composed of causal “driver” mutations that promote tumor progression along with many more pathologically neutral “passenger” events. The majority of mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f5fd1bcfadf61c054a30049bdf9add
https://doi.org/10.1158/0008-5472.c.6507206.v1
https://doi.org/10.1158/0008-5472.c.6507206.v1
Autor:
Kenneth L. Scott, Gordon B. Mills, Ken Chen, Chad J. Creighton, Penelope E. Bonnen, Agna Karina Eterovic, Armel Dogruluk, Vivek Appadurai, Zechen Chong, Tenghui Chen, Fengju Chen, Maribel Espitia, Yiu Huen Tsang, Turgut Dogruluk
MCF10A cell growth is dependent on insulin and epidermal growth factor (S1); RPPA analysis (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ca58b490b96aad01f4f419c33b9e5f
https://doi.org/10.1158/0008-5472.22406978.v1
https://doi.org/10.1158/0008-5472.22406978.v1
Autor:
Mengyuan Liu, Chunhua Shi, Jiucun Wang, Xiaodong Zhou, Maribel Espitia, Shervin Assassi, Hongye Li, Xinjian Guo, Qingwen Wang, Maureen D. Mayes, John D. Reveille, Shicheng Guo
Publikováno v:
The Journal of Rheumatology. 46:184-189
Objective.Findings from previous genome-wide association studies indicated an association of theNOTCH4gene with systemic sclerosis (SSc). This is a followup study to fine-map exonic variants ofNOTCH4in SSc.Methods.All exons ofNOTCH4were sequenced and
Autor:
Penelope E. Bonnen, Turgut Dogruluk, Agna Karina Eterovic, Ken Chen, Gordon B. Mills, Fengju Chen, Vivek Appadurai, Tenghui Chen, Chad J. Creighton, Maribel Espitia, Kenneth L. Scott, Armel Dogruluk, Zechen Chong, Yiu Huen Tsang
Publikováno v:
Cancer Research. 75:5341-5354
Large-scale sequencing efforts are uncovering the complexity of cancer genomes, which are composed of causal “driver” mutations that promote tumor progression along with many more pathologically neutral “passenger” events. The majority of mut
Autor:
Xiaodong, Zhou, Hongye, Li, Shicheng, Guo, Jiucun, Wang, Chunhua, Shi, Maribel, Espitia, Xinjian, Guo, Qingwen, Wang, Mengyuan, Liu, Shervin, Assassi, John D, Reveille, Maureen D, Mayes
Publikováno v:
The Journal of rheumatology. 46(2)
Findings from previous genome-wide association studies indicated an association of theAll exons ofA total of 12 SSc-associated and SSc subtype-associated exonic variants ofMultiple
Autor:
Qing Edward Chang, Ken Chen, Maribel Espitia, Haoqiang Ying, Yiu Huen Tsang, Turgut Dogruluk, John Kerrigan, Fengju Chen, Joanna Wardwell-Ozgo, Marie-Claude Gingras, Joseph R. Bertino, Chad J. Creighton, Gordon B. Mills, Nikitha Nair, Kenneth L. Scott, Armel Dogruluk, Rosalba Minelli, Hengyu Lu, Michael Ittmann, Karina Eterovic, Zechen Chong, Jennifer B. Dennison, Philip M. Tedeschi, Min Li
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
As we enter the era of precision medicine, characterization of cancer genomes will directly influence therapeutic decisions in the clinic. Here we describe a platform enabling functionalization of rare gene mutations through their high-throughput con