Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mariarosa Anna Beatrice Melone"'
Autor:
Laura De Rosa, Dominga Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Nunzia Mollo, Giuseppina Amodio, Elena Polishchuk, Roman Polishchuk, Mariarosa Anna Beatrice Melone, Chiara Criscuolo, Anna Conti, Lucio Nitsch, Paolo Remondelli, Giovanna Maria Pierantoni, Simona Paladino
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Endosomal trafficking is essential for cellular homeostasis. At the crossroads of distinct intracellular pathways, the endolysosomal system is crucial to maintain critical functions and adapt to the environment. Alterations of endosomal compartments
Externí odkaz:
https://doaj.org/article/bb7c01ded3ef4671ac7aa624d3cba628
Autor:
Rosina Paterra, Paola Bettinaglio, Arianna Borghi, Eleonora Mangano, Viviana Tritto, Claudia Cesaretti, Carla Schettino, Roberta Bordoni, Claudia Santoro, Sabrina Avignone, Marco Moscatelli, Mariarosa Anna Beatrice Melone, Veronica Saletti, Giulio Piluso, Federica Natacci, Paola Riva, Marica Eoli
Publikováno v:
Cancers, Vol 15, Iss 1, p 59 (2022)
Spinal neurofibromatosis (SNF), a phenotypic subclass of neurofibromatosis 1 (NF1), is characterized by bilateral neurofibromas involving all spinal roots. In order to deepen the understanding of SNF’s clinical and genetic features, we identified 8
Externí odkaz:
https://doaj.org/article/638a9dd91c1544bc99b4aa3afa9cc78f
Autor:
Claudia Riccardi, Federica D’Aria, Dominga Fasano, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12412 (2022)
Two analogues of the MS3 aptamer, which was previously shown to have an exquisite capability to selectively bind and modulate the activity of mutant huntingtin (mHTT), have been here designed and evaluated in their physicochemical and biological prop
Externí odkaz:
https://doaj.org/article/9ee2118330bc416e9eb9c2c184cb036c
Autor:
Vincenzo De Luca, Giovanni Tramontano, Luigi Riccio, Ugo Trama, Pietro Buono, Mario Losasso, Umberto Marcello Bracale, Giovanni Annuzzi, Rosa Zampetti, Francesco Cacciatore, Giannamaria Vallefuoco, Alberto Lombardi, Anna Marro, Mariarosa Anna Beatrice Melone, Cristina Ponsiglione, Maria Luisa Chiusano, Giancarlo Bracale, Gaetano Cafiero, Aurelio Crudeli, Carmine Vecchione, Maurizio Taglialatela, Donatella Tramontano, Guido Iaccarino, Maria Triassi, Regina Roller-Wirnsberger, Jean Bousquet, Maddalena Illario
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
This article describes how innovations are exploited in Campania (Italy) to improve health outcomes, quality of life, and sustainability of social and healthcare services. Campania's strategy for digitalization of health and care and for healthy agin
Externí odkaz:
https://doaj.org/article/a37bcd62d0ee4cde9a8c1c26aeac944a
Autor:
Filomena Napolitano, Milena Dell’Aquila, Chiara Terracciano, Giuseppina Franzese, Maria Teresa Gentile, Giulio Piluso, Claudia Santoro, Davide Colavito, Anna Patanè, Paolo De Blasiis, Simone Sampaolo, Simona Paladino, Mariarosa Anna Beatrice Melone
Publikováno v:
Genes, Vol 13, Iss 7, p 1130 (2022)
Neurofibromatosis type 1 (NF1) is one of the most common genetic tumor predisposition syndrome, caused by mutations in the NF1. To date, few genotype-phenotype correlations have been discerned in NF1, due to a highly variable clinical presentation. W
Externí odkaz:
https://doaj.org/article/804878effeb94049b30b5816ff1324d8
Autor:
Claudia Riccardi, Federica D’Aria, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Dominga Fasano, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4804 (2022)
A set of guanine-rich aptamers able to preferentially recognize full-length huntingtin with an expanded polyglutamine tract has been recently identified, showing high efficacy in modulating the functions of the mutated protein in a variety of cell ex
Externí odkaz:
https://doaj.org/article/411736ef4fe64fc09f290756716f5a0a
Autor:
Claudia Riccardi, Filomena Napolitano, Daniela Montesarchio, Simone Sampaolo, Mariarosa Anna Beatrice Melone
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1897 (2021)
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related disorders featured by progressive impairment of motor and/or cognitive functions, often accompanied by psychiatric disorders. NDs are denoted as ‘protein misfolding
Externí odkaz:
https://doaj.org/article/77b1725d6d8240d79aa8a62667fd7ff4
Autor:
Filomena Napolitano, Giorgia Bruno, Chiara Terracciano, Giuseppina Franzese, Nicole Piera Palomba, Federica Scotto di Carlo, Elisabetta Signoriello, Paolo De Blasiis, Stefano Navarro, Alessandro Gialluisi, Mariarosa Anna Beatrice Melone, Simone Sampaolo, Teresa Esposito
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3625 (2021)
Pompe disease is an autosomal recessive disorder caused by a deficiency in the enzyme acid alpha-glucosidase. The late-onset form of Pompe disease (LOPD) is characterized by a slowly progressing proximal muscle weakness, often involving respiratory m
Externí odkaz:
https://doaj.org/article/3a2dc99a2036456ca042de84dd8ca566
Autor:
Alessandro Vaisfeld, Giorgia Bruno, Martina Petracca, Anna Rita Bentivoglio, Serenella Servidei, Maria Gabriella Vita, Francesco Bove, Giulia Straccia, Clemente Dato, Giuseppe Di Iorio, Simone Sampaolo, Silvio Peluso, Anna De Rosa, Giuseppe De Michele, Melissa Barghigiani, Daniele Galatolo, Alessandra Tessa, Filippo Santorelli, Pietro Chiurazzi, Mariarosa Anna Beatrice Melone
Publikováno v:
Genes, Vol 12, Iss 3, p 344 (2021)
Neuroacanthocytosis (NA) syndromes are a group of genetically defined diseases characterized by the association of red blood cell acanthocytosis, progressive degeneration of the basal ganglia and neuromuscular features with characteristic persistent
Externí odkaz:
https://doaj.org/article/4a2d44a824a54e97b829a852dedc869d
Autor:
Francesca Di Cristo, Anna Calarco, Filomena Anna Digilio, Maria Stefania Sinicropi, Camillo Rosano, Umberto Galderisi, Mariarosa Anna Beatrice Melone, Carmela Saturnino, Gianfranco Peluso
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7431 (2020)
A mismatch between β-oxidation and the tricarboxylic acid cycle (TCA) cycle flux in mitochondria produces an accumulation of lipid metabolic intermediates, resulting in both blunted metabolic flexibility and decreased glucose utilization in the affe
Externí odkaz:
https://doaj.org/article/296c914a518d45c1b24fa68ea3186b7b