Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Mariapia Vairetti"'
Autor:
Laura Giuseppina Di Pasqua, Murwan Mahmoud Abdallah, Fausto Feletti, Mariapia Vairetti, Andrea Ferrigno
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 484 (2024)
Venetoclax is a Bcl-2 homology domain 3 (BH3) mimetic currently approved for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) that has proven to be highly effective in reinstating apoptosis in leukemic cells throug
Externí odkaz:
https://doaj.org/article/b3a6ff91f66c49feaa6d03bcb424a06c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4010 (2024)
The aim of this Special Issue is to provide an update on the diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD), which is the most prevalent liver disease worldwide; however, there are still no specific treatment agents [...]
Externí odkaz:
https://doaj.org/article/e4b7f06fff4342a4ada53354424071c6
Autor:
Giuseppina Palladini, Laura Giuseppina Di Pasqua, Anna Cleta Croce, Andrea Ferrigno, Mariapia Vairetti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17407 (2023)
The reversion-inducing cysteine-rich protein with Kazal motifs (RECK), a membrane-anchored glycoprotein, negatively regulates various membrane proteins involved in the tissue governing extracellular matrix (ECM) remodeling such as metalloproteases (M
Externí odkaz:
https://doaj.org/article/f7ec502f96bb470b95604a8f3231b30b
Autor:
Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
Publikováno v:
European Journal of Histochemistry, Vol 66, Iss 4 (2022)
We have investigated the change in SerpinB3 during hepatic ischemia and the potential role of its antiprotease activity in cell protection by the administration of wild-type SerpinB3 (SerpinB3-WT) or active loop-deleted recombinant SerpinB3 protein (
Externí odkaz:
https://doaj.org/article/132dd393be9445019719bfe2e49b6ede
Autor:
Andrea Ferrigno, Lucrezia Irene Maria Campagnoli, Annalisa Barbieri, Nicoletta Marchesi, Alessia Pascale, Anna Cleta Croce, Mariapia Vairetti, Laura Giuseppina Di Pasqua
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9808 (2023)
The endogenous antioxidant defense plays a big part in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), a common metabolic disorder that can lead to serious complications such as cirrhosis and cancer. HuR, an RNA-binding protein of the
Externí odkaz:
https://doaj.org/article/12d1d5347404437fbed7651f2c4fef4d
Autor:
Laura Giuseppina Di Pasqua, Clarissa Berardo, Marta Cagna, Barbara Mannucci, Gloria Milanesi, Anna Cleta Croce, Andrea Ferrigno, Mariapia Vairetti
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Waiting lists that continue to grow and the lack of organs available for transplantation necessitate the use of marginal livers, such as fatty livers. Since steatotic livers are more susceptible to damage from ischemia and reperfu
Externí odkaz:
https://doaj.org/article/86f756e8e13e4405b19889424d2615e1
Autor:
Anna C. Croce, Andrea Ferrigno, Giuseppina Palladini, Barbara Mannucci, Mariapia Vairetti, Laura G. Di Pasqua
Publikováno v:
Molecules, Vol 28, Iss 9, p 3818 (2023)
The autofluorescence of specific fatty acids, retinoids, and bilirubin in crude serum can reflect changes in liver functional engagement in maintaining systemic metabolic homeostasis. The role of these fluorophores as intrinsic biomarkers of pharmaco
Externí odkaz:
https://doaj.org/article/7416e569fc0a4d9dbb07fdf01b8a233a
Autor:
Andrea Ferrigno, Marta Cagna, Oriana Bosco, Michelangelo Trucchi, Clarissa Berardo, Ferdinando Nicoletti, Mariapia Vairetti, Laura G. Di Pasqua
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6076 (2023)
The blockade of metabotropic glutamate receptor type 5 (mGluR5) was previously found to reduce fat accumulation in HEPG2 cells. Here, we evaluated the effects of mGluR5 blockade in a mouse model of steatosis. Male ob/ob mice fed a high-fat diet were
Externí odkaz:
https://doaj.org/article/b164945d279e4700b9743315ab9ba7b8
Autor:
Lucrezia Irene Maria Campagnoli, Nicoletta Marchesi, Mariapia Vairetti, Alessia Pascale, Andrea Ferrigno, Annalisa Barbieri
Publikováno v:
Cells, Vol 11, Iss 18, p 2827 (2022)
Human aging, a natural process characterized by structural and physiological changes, leads to alterations of homeostatic mechanisms, decline of biological functions, and subsequently, the organism becomes vulnerable to external stress or damage. In
Externí odkaz:
https://doaj.org/article/4406394dce1046e6b1098a3c53e18785
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7894 (2022)
Nonalcoholic fatty liver disease (NAFLD) is among the most common liver diseases worldwide, affecting up to 20–30% of the human population [...]
Externí odkaz:
https://doaj.org/article/74f9ee80469e43bf805b84e4d7080ee3