Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marianyela Petrizzelli"'
Publikováno v:
Royal Society Open Science, Vol 11, Iss 10 (2024)
The way biological systems respond to changes in parameter values caused by mutations is a key issue in evolution and quantitative genetics, as it affects fundamental aspects such as adaptation, selective neutrality, robustness, optimality, evolution
Externí odkaz:
https://doaj.org/article/05395728bb3845d09d5f3e7a7be2c53f
Autor:
Iker Núñez-Carpintero, Marianyela Petrizzelli, Andrei Zinovyev, Davide Cirillo, Alfonso Valencia
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102365- (2021)
Summary: Multilayer networks allow interpreting the molecular basis of diseases, which is particularly challenging in rare diseases where the number of cases is small compared with the size of the associated multi-omics datasets. In this work, we dev
Externí odkaz:
https://doaj.org/article/c4d73bcd932c4c1eac16b7d6031b0f2d
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Recombinant Inbred Lines (RILs) are obtained through successive generations of inbreeding. In 1931 Haldane and Waddington published a landmark paper where they provided the probabilities of achieving any combination of alleles in 2-way RILs for 2 and
Externí odkaz:
https://doaj.org/article/7059564f51434bf8a07201186dfaff2e
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2226
Ewing sarcoma (EwS) is a highly aggressive pediatric bone cancer that is defined by a somatic fusion between the EWSR1 gene and an ETS family member, most frequently the FLI1 gene, leading to expression of a chimeric transcription factor EWSR1-FLI1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4df94f2f543cfe04a1672ffc0e6b4bb
https://pubmed.ncbi.nlm.nih.gov/33326111
https://pubmed.ncbi.nlm.nih.gov/33326111
Autor:
Marianyela Petrizzelli, Camille Noûs, Dominique de Vienne, Thibault Nidelet, Christine Dillmann
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Public Library of Science, 2021, 17 (7), ⟨10.1371/journal.pcbi.1009157⟩
PLoS Computational Biology, Vol 17, Iss 7, p e1009157 (2021)
PLoS Computational Biology, Public Library of Science, 2021, 17 (7), ⟨10.1371/journal.pcbi.1009157⟩
PLoS Computational Biology, Vol 17, Iss 7, p e1009157 (2021)
The relationship between different levels of integration is a key feature for understanding the genotype-phenotype map. Here, we describe a novel method of integrated data analysis that incorporates protein abundance data into constraint-based modeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0e9772c81f48a2dcc08dac832cb504
https://doi.org/10.1101/2020.06.23.166405
https://doi.org/10.1101/2020.06.23.166405
Publikováno v:
Ewing Sarcoma Methods and Protocols
Ewing Sarcoma Methods and Protocols, 2226, pp.303-333, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1020-6_23⟩
Methods in Molecular Biology ISBN: 9781071610190
Ewing Sarcoma Methods and Protocols, 2226, pp.303-333, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1020-6_23⟩
Methods in Molecular Biology ISBN: 9781071610190
Ewing sarcoma (EwS) is a highly aggressive pediatric bone cancer that is defined by a somatic fusion between the EWSR1 gene and an ETS family member, most frequently the FLI1 gene, leading to expression of a chimeric transcription factor EWSR1-FLI1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc9fc116737bb58e7b1f56dd1ab0876
Publikováno v:
Genetics
Genetics, Genetics Society of America, 2019, 211 (2), pp.741-756. ⟨10.1534/genetics.118.301635⟩
www.genetics.org
Genetics, Genetics Society of America, 2019, 211 (2), pp.741-756. ⟨10.1534/genetics.118.301635⟩
www.genetics.org
Heterosis (hybrid vigor) and inbreeding depression, commonly considered as corollary phenomena, could nevertheless be decoupled under certain assumptions according to theoretical population genetics works. In order to explore this issue on real data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872a891f89735aeab2883dfe8eabad5b
https://europepmc.org/articles/PMC6366921/
https://europepmc.org/articles/PMC6366921/
Supplemental Material for the study “Decoupling the variances of heterosis and inbreeding effects is evidenced in yeast’s life-history and proteomic traits”, by Petrizzelli et al. 2018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c5a6dce9711da41ee4cc96ae418bba