Výsledky vyhledávání - "Mariantonietta Scafuro"

Neuroimmune-Driven Neuropathic Pain Establishment: A Focus on Gender Differences

Autor: Francesca Guida, Mariantonietta Scafuro, Livio Luongo, Serena Boccella, Vincenzo Coraggio, Domenico Romano, Sabatino Maione, Salvatore Paino

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 1, p 281 (2018)

The role of neuroinflammatory cells in the establishment of neuropathic pain has been investigated in depth in the last few years. In particular, microglia have been shown to be key players in the induction of tactile allodynia, as they release proin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f218755854471fa9c655f0d0fea023
https://doi.org/10.3390/ijms19010281

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1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice

Autor: Catia Giordano, P Lazzari, Marzia Malcangio, Sabatino Maione, Livio Luongo, F. sca Rossi, L Pani, Mariantonietta Scafuro, Luisa Gatta, V. de Novellis, Enza Palazzo, S Tambaro

Publikováno v: Neurobiology of disease 37 (2010): 177–185.
info:cnr-pdr/source/autori:Luongo L, Palazzo E, Tambaro S, Giordano C, Gatta L, Scafuro MA, Rossi FS, Lazzari P, Pani L, de Novellis V, Malcangio M, Maione S./titolo:1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice./doi:/rivista:Neurobiology of disease/anno:2010/pagina_da:177/pagina_a:185/intervallo_pagine:177–185/volume:37
Neurobiology of Disease, Vol 37, Iss 1, Pp 177-185 (2010)

Neuropathic pain is a devastating neurological disease that seriously affects quality of life in patients. The mechanisms leading to the development and maintenance of neuropathic pain are still poorly understood. However, recent evidence points towa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ef00f7893e7f0b7311732ee2575e4f
https://doi.org/10.1016/j.nbd.2009.09.021

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Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice

Autor: Daniela Vita, Ida Marabese, Enza Palazzo, Mariantonietta Scafuro, V. de Novellis, Sabatino Maione, F. Rossi

Publikováno v: Neuropharmacology. 52:253-262

In this study, the effect of ( S )-3,4-dicarboxyphenylglycine (DCPG), a selective mGlu8 receptor agonist, has been investigated in inflammatory and neuropathic pain models in order to elucidate the role of mGlu8 receptor in modulating pain perception

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dad14ae075b50779da486d3cf57f6f4
https://doi.org/10.1016/j.neuropharm.2006.04.006

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Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat

Autor: Loredana Mariani, Daniela Vita, Mariantonietta Scafuro, F. Rossi, Sabatino Maione, V. de Novellis, Ida Marabese, Enza Palazzo

Publikováno v: Neuroscience. 134:269-281

This study was undertaken to analyze the involvement of periaqueductal gray (PAG) cannabinoid or group I metabotropic glutamate receptors in the formalin-induced changes on the rostral ventromedial medulla (RVM) ON- and OFF-cells activities. S.c. inj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da040e986311cbaa08d6733270f82cd3
https://doi.org/10.1016/j.neuroscience.2005.03.014

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Percutaneous thermocoagulation of the Gasserian ganglion in the treatment of trigeminal neuralgia

Autor: Ciro Parlato, Marco Moraci, Laura Columbano, Mario Giordano, Aldo Moraci, Mariantonietta Scafuro, Luigi Frascadore

Publikováno v: The Pain Clinic. 16:393-399

Objective: To validate the use of selective percutaneous thermocoagulation of the Gasserian ganglion in the treatment of trigeminal neuralgia. Methods: 1860 patients with trigeminal neuralgia (TN) were studied over a period of 26 years. Diagnosis was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fd6ad13027fb1f7139a99bd44a693db
https://doi.org/10.1163/1568569042664440

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Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat

Autor: Serena Boccella, Vito de Novellis, Enza Palazzo, Giulia Bellini, Maria Elvira Giordano, Livio Luongo, Sabatino Maione, Mariantonietta Scafuro, Ida Marabese, Francesca Rossi

Publikováno v: Molecular Pain

The metabotropic glutamate receptor 7 (mGluR7) negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), was locally microinjected into the ventrolateral periaqueductal gray (VL PAG) and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cd2a683f12991134fdf01f030aba33
http://hdl.handle.net/11591/182340

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The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy

Autor: Livio Luongo, Pierangelo Orlando, Sabatino Maione, Dario Siniscalco, Francesca Rossi, Stefania Petrosino, Silvia Mancusi, Mariantonietta Scafuro, Vincenzo Di Marzo, Bruno Nobili, Luciano De Petrocellis, Silverio Perrotta, Marco Torella, Nicola Colacurci, Giulia Bellini

Publikováno v: Bone (New York, NY) 48 (2011): 997–1007. doi:10.1016/j.bone.2011.01.001
info:cnr-pdr/source/autori:Rossi F, Bellini G, Luongo L, Torella M, Mancusi S, De Petrocellis L, Petrosino S, Siniscalco D, Orlando P, Scafuro M, Colacurci N, Perrotta S, Nobili B, Di Marzo V, Maione S./titolo:The endovanilloid%2Fendocannabinoid system: a new potential target for osteoporosis therapy./doi:10.1016%2Fj.bone.2011.01.001/rivista:Bone (New York, NY)/anno:2011/pagina_da:997/pagina_a:1007/intervallo_pagine:997–1007/volume:48

Human osteoclasts express functional TRPV1 channels, CB1/CB2 cannabinoid receptors and endocannabinoid/endovanilloid synthetic/catabolic enzymes. Pharmacologic manipulation of this system can modulate osteoclast activity. Here, through multidisciplin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf3a4b87eb63c2272075d5042f032ea
http://hdl.handle.net/11591/187100

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