Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marianthi Kiparaki"'
Autor:
Marianthi Kiparaki, Nicholas E. Baker
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102653- (2023)
Summary: Translation is a fundamental process of cellular behavior. Here, we present a protocol for measuring translation in Drosophila epithelial tissues using O-propargyl-puromycin (OPP), a puromycin derivative. We detail steps for larval dissectio
Externí odkaz:
https://doaj.org/article/d9b70a07545941f3b251d7ab38c56803
Autor:
Marianthi Kiparaki, Chaitali Khan, Virginia Folgado-Marco, Jacky Chuen, Panagiotis Moulos, Nicholas E Baker
Publikováno v:
eLife, Vol 11 (2022)
Ribosomal Protein (Rp) gene haploinsufficiency affects translation rate, can lead to protein aggregation, and causes cell elimination by competition with wild type cells in mosaic tissues. We find that the modest changes in ribosomal subunit levels o
Externí odkaz:
https://doaj.org/article/a9adcb8fd2294cfcaa650d9525294658
Publikováno v:
eLife, Vol 10 (2021)
Aneuploidy causes birth defects and miscarriages, occurs in nearly all cancers and is a hallmark of aging. Individual aneuploid cells can be eliminated from developing tissues by unknown mechanisms. Cells with ribosomal protein (Rp) gene mutations ar
Externí odkaz:
https://doaj.org/article/81c5fc7ac16c4f4989dc49c946e427f1
Autor:
Zhejun Ji, Marianthi Kiparaki, Virginia Folgado, Amit Kumar, Jorge Blanco, Gerard Rimesso, Jacky Chuen, Yang Liu, Deyou Zheng, Nicholas E Baker
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008513 (2019)
Whereas complete loss of Rp function is generally lethal, most heterozygous Rp mutants grow more slowly and are subject to competitive loss from mosaics tissues that also contain wild type cells. The rpS12 gene has a special role in the cell competit
Externí odkaz:
https://doaj.org/article/9f20339a45b04c3d80e3e3d46ab1a888
Ribosomal Protein (Rp) gene haploinsufficiency affects overall translation rate, leads to cell elimination by competition with wild type cells in mosaic tissues, and sometimes leads to accumulation of protein aggregates. The changes in ribosomal subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0edee7d8cc06086507f83ffa132bd28f
https://doi.org/10.1101/2021.07.12.452023
https://doi.org/10.1101/2021.07.12.452023
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Aneuploidy causes birth defects and miscarriages, occurs in nearly all cancers and is a hallmark of aging. Individual aneuploid cells can be eliminated from developing tissues by unknown mechanisms. Cells with ribosomal protein (Rp) gene mutations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7fadd9cad843d562fab03dd82180b0
https://elifesciences.org/articles/61172
https://elifesciences.org/articles/61172
Aneuploidy causes birth defects and miscarriages, occurs in nearly all cancers, and is a hallmark of aging. Individual aneuploid cells can be eliminated from developing tissues by unknown mechanisms. Cells with ribosomal protein (Rp) gene mutations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02e1fa945c7b0c84e5f6c30ae7a10da
https://doi.org/10.1101/2021.03.05.433802
https://doi.org/10.1101/2021.03.05.433802
Autor:
Jorge Blanco, Marianthi Kiparaki, Nicholas E. Baker, Amit Kumar, Deyou Zheng, Virginia Folgado, Zhejun Ji, Jacky Chuen, Gerard Rimesso, Yang Liu
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008513 (2019)
PLoS Genetics
PLoS Genetics
Whereas complete loss of Rp function is generally lethal, most heterozygous Rp mutants grow more slowly and are subject to competitive loss from mosaics tissues that also contain wild type cells. The rpS12 gene has a special role in the cell competit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cd4f9269c5e4540894d02c453768d5
https://doaj.org/article/9f20339a45b04c3d80e3e3d46ab1a888
https://doaj.org/article/9f20339a45b04c3d80e3e3d46ab1a888