Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mariano Tabios"'
Autor:
Maru Jaime-Garza, Carlos A. Nowotny, Daniel Coutandin, Feng Wang, Mariano Tabios, David A. Agard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The Hsp90 molecular chaperone collaborates with the phosphorylated Cdc37 cochaperone for the folding and activation of its many client kinases. As with many kinases, the Hsp90 client kinase CRaf is activated by phosphorylation at specific re
Externí odkaz:
https://doaj.org/article/f4dae4dff3af402bb7da3cc3f3e9e00c
Autor:
Gregory D. Plowman, Casey Kopczynski, Kim Lickteig, Lori Friedman, Christopher G. Winter, Matt B. Mahoney, Kellie Whittaker, Helen Francis-Lang, Marcia Belvin, Matthew V. Lorenzi, Ferhad Ahmad, Hanife Esengil, Annette L. Parks, Brent A. Rupnow, Monique Nicoll, Feng Chen, Lynn M. Young, Mariano Tabios, Kyle A. Edgar, Christopher C. Park, Amanda Norton, Laleh Shayesteh, Pamela M. Carroll
Publikováno v:
Genetics. 170:161-171
Mutations that inactivate the retinoblastoma (Rb) pathway are common in human tumors. Such mutations promote tumor growth by deregulating the G1 cell cycle checkpoint. However, uncontrolled cell cycle progression can also produce new liabilities for
Autor:
Jennifer E Deal, Geoffrey Duyk, Kyle A. Edgar, Kevin P Bogart, Christopher G. Winter, Matthew A Singer, Daniel Tim Curtis, Robert Fawcett, Lory R Tan, Valentina Vysotskaia, Wesley Y Miyazaki, Casey Kopczynski, Kari Huppert, Marie Marcinko, Elizabeth Howie, Millicent A Winner, Doua Thao, Kellie Whittaker, Nicholas A Dompe, Jonathan Margolis, Deanna Grant, Rachel S. Andrade, Gregory D. Plowman, Marcia Belvin, Mariano Tabios, Megan E Deal-Herr, Helen Francis-Lang, Amanda Norton, Lora Zhao, Stephanie A. Robertson, Annette L. Parks, Lori Friedman, Kenneth J. Shaw, Kevin R. Cook, Keith Killpack, Brett Milash, Thomas C. Kaufman
Publikováno v:
Nature Genetics. 36:288-292
In fruit fly research, chromosomal deletions are indispensable tools for mapping mutations, characterizing alleles and identifying interacting loci. Most widely used deletions were generated by irradiation or chemical mutagenesis. These methods are l