Výsledky vyhledávání - "Mariano Schiavon"

New findings on the in vivo antioxidant activity of Curcuma longa extract by an integrated 1H NMR and HPLC-MS metabolomic approach

Autor: Irene Boschiero, Jalal Uddin, Elisabetta Schievano, Mariano Schiavon, Stefano Mammi, Matteo Stocchero, Stefano Dall'Acqua, Samuel Golob, Dario Voinovich

Curcuminoids possess powerful antioxidant activity as demonstrated in many chemical in vitro tests and in several in vivo trials. Nevertheless, the mechanism of this activity is not completely elucidated and studies on the in vivo antioxidant effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d263dbe711953c02557fc7455de5032c
http://hdl.handle.net/11577/3182472

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Poly(ethylene glycol)-mesalazine conjugate for colon specific delivery

Autor: Paola Brun, Ignazio Castagliuolo, Mariano Schiavon, Fm Veronese, Mirta Canevari, Gianfranco Pasut, M Cardin

Publikováno v: International Journal of Pharmaceutics. 368:171-177

Chronic inflammatory bowel diseases (IBDs) are still waiting for improved and innovative therapeutic treatments, which can overcome the limits of the current approaches. Since IBDs affect mainly the lower tract of the intestine, a localized therapy i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8275ea10231d25052e84291f43e60c
https://doi.org/10.1016/j.ijpharm.2008.09.058

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Changes in urinary metabolic profile after oral administration of curcuma extract in rats

Autor: Stefano Dall'Acqua, Mariano Schiavon, Matteo Stocchero, Stefano Mammi, Maria Clauser, Emmanuel Ndoum, Elisabetta Schievano, Irene Boschiero

Publikováno v: Journal of pharmaceutical and biomedical analysis. 100

The diffusion of phytochemicals in health promoting products is growing, but studies related to their effects on healthy subjects are still lacking despite the large consumption of natural products as nutraceuticals or food supplements. In many cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d55ed37bcce6532311d7a00aa69784e
https://pubmed.ncbi.nlm.nih.gov/25200426

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Heterocyclic Derivatives ofall-transRetinoic Acid:in vitroEffects on Fibroblast/Keratinocyte Growth and Differentiation, andin vivoEffects on Guinea-Pig Skin

Autor: Chiara Bortoletto, Francesco Maria Cancellotti, Maria Teresa Conconi, Stefano Manfredini, Mariano Schiavon, Pier Paolo Parnigotto, Francesco Montesi

Publikováno v: Pharmacology & Toxicology. 85:49-55

We investigated the biological effects of five all-trans retinoic acid derivatives, bearing heterocyclic ring systems in the side chain. Growth assays performed on submerged human fibroblast and keratinocyte cultures revealed that (E)4-[2-(5-terbuthy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8e760e1b2503b0a6dd58fcadf5679c
https://doi.org/10.1111/j.1600-0773.1999.tb00066.x

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A new method to increase selectivity of transglutaminase mediated PEGylation of salmon calcitonin and human growth hormone

Autor: Anna Mero, Mariano Schiavon, Francesco M. Veronese, Gianfranco Pasut

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society. 154(1)

Modification of therapeutic proteins and peptides by polyethylene glycol (PEG) conjugation is a well-known approach to improve the pharmacological properties of drugs. Several chemical procedures of PEG coupling are already in use but an alternative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2925ae7fadfdb1910997d2265b74128
https://pubmed.ncbi.nlm.nih.gov/21565230

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A New Class of Antitumor trans-Amine-Amidine-Pt(II) Cationic Complexes: Influence of Chemical Structure and Solvent on in Vitro and in Vivo Tumor Cell Proliferation

Autor: Davide Colavito, Rino A. Michelin, Roberta Seraglia, Silvia Mazzega Sbovata, Mariano Schiavon, Valentina Gandin, Franco Benetollo, Alfonso Venzo, Elda Del Giudice, Cristina Marzano, Roberta Bertani

Publikováno v: Journal of medicinal chemistry 53 (2010): 6210–6227. doi:10.1021/jm1006534
info:cnr-pdr/source/autori:Marzano C.; Sbovata S.M.; Gandin V.; Colavito D.; Del Giudice E.; Michelin R.A.; Venzo A.; Seraglia R.; Benetollo F.; Schiavon M.; Bertani, R./titolo:A New Class of Antitumor trans-Amine-Amidine-Pt(II) Cationic Complexes: Influence of Chemical Structure and Solvent on in Vitro and in Vivo Tumor Cell Proliferation/doi:10.1021%2Fjm1006534/rivista:Journal of medicinal chemistry/anno:2010/pagina_da:6210/pagina_a:6227/intervallo_pagine:6210–6227/volume:53

The reactions of cyclopropylamine, cyclopentylamine, and cyclohexylamine with trans-[PtCl2(NCMe)(2)] afforded the bis-cationic complexes trans-[Pt(amine)(2)(Z-amidine)(2)](2+)[Cl-](2), 1-3, The solution behavior and biological activity have been stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07940d889baf42259c329518953f5d4d
http://hdl.handle.net/11577/2449277

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Akademický článek

A New Class of Antitumor trans-Amine-Amidine-Pt(II) Cationic Complexes: Influence of Chemical Structure and Solvent on in Vitro and in Vivo Tumor Cell Proliferation.

Autor: Cristina Marzano, Silvia Mazzega Sbovata, Valentina Gandin, Davide Colavito, Elda Del Giudice, Rino A. Michelin, Alfonso Venzo, Roberta Seraglia, Franco Benetollo, Mariano Schiavon, Roberta Bertani

Publikováno v: Journal of Medicinal Chemistry; Aug2010, Vol. 53 Issue 16, p6210-6227, 18p

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