Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Mariano Janiszewski"'
Publikováno v:
Revista Brasileira de Terapia Intensiva, Vol 20, Iss 3, Pp 321-322 (2008)
Externí odkaz:
https://doaj.org/article/9c24b5288aa34f56a3eb79253acb39f5
Autor:
Allegra Kaufman, Elizabeth C. Finger, Cheng Su, Winnie Sohn, Yi Hsiang Hsu, Mariano Janiszewski
Publikováno v:
Journal of the American College of Cardiology. 73:1755
Heterozygous carriers of a rare 12-base-pair deletion (del12), loss-of-function variant in the asialoglycoprotein receptor (ASGPR) subunit 1 ( ASGR1 ) had lower levels of non-high-density lipoprotein cholesterol, reduced risk for myocardial infarctio
Autor:
Karina Ckless, Mariano Janiszewski, Marcia C. Jurado, Daniella Oxer, Luiz C. Godoy, Ana Iochabel Soares Moretti, Irineu Tadeu Velasco, Francisco R.M. Laurindo, Heraldo Possolo de Souza
Publikováno v:
Shock. 33:626-633
Signal transduction through the surface molecule CD40 is critical for cellular activation in immunoinflammatory states such as sepsis. The mechanisms regulating this pathway are not completely understood. Because CD40 displays potentially regulatory
Publikováno v:
Free Radical Biology and Medicine. 41:193-201
NADPH oxidase is the most important source of oxygen-derived radicals (ROS) in the vascular wall. In vascular smooth muscle cells (VSMC), NADPH oxidase is characterized by the expression of the membrane subunit Nox1, which is activated by cytoplasmic
Autor:
MA Pedro, Lucia Rossetti Lopes, Alipio O. Carmo, Célio X.C. Santos, Ralf P. Brandes, Mariano Janiszewski, Francisco R.M. Laurindo
Publikováno v:
Journal of Biological Chemistry. 280:40813-40819
NAD(P)H oxidase, the main source of reactive oxygen species in vascular cells, is known to be regulated by redox processes and thiols. However, the nature of thiol-dependent regulation has not been established. Protein disulfide isomerase (PDI) is a
Autor:
Tomasz Panz, Jacek Miedzobrodzki, Mariano Janiszewski, Rafał Olszanecki, Francisco R.M. Laurindo, Stefan Chlopicki
Publikováno v:
Antioxidants & Redox Signaling. 6:691-698
Involvement of phagocyte NADPH oxidase in host defense response is well established. In contrast, little is known about the functional role of NADPH oxidase in platelets. In this study, we analyzed involvement of platelet NADPH oxidase in aggregation
Autor:
Mariano Janiszewski, Eliezer Silva, Elias Knobel, Francisco R.M. Laurindo, Alipio O. Carmo, MA Pedro
Publikováno v:
Critical Care Medicine. 32:818-825
Vascular dysfunction in sepsis may involve apoptosis of vascular cells through redox signaling mechanisms, which are still poorly investigated. Platelets have been shown to produce reactive oxygen species and to release microparticles, related to thr
Autor:
H. P. Souza, MA Pedro, Jay L. Zweier, Francisco R.M. Laurindo, Mariano Janiszewski, Xiaoping Liu
Publikováno v:
Free Radical Biology and Medicine. 32:446-453
Several limitations have recently been described for lucigenin, a probe frequently used to assess the activity of vascular NAD(P)H oxidase, a major superoxide source. The preferential reducing substrate of such oxidase remains unclear. We assessed wh
Publikováno v:
Revista Brasileira de terapia intensiva. 20(3)
Autor:
Ohara Augusto, Liliete Canes Souza, Francisco R.M. Laurindo, MA Pedro, Jan-Thies H. van Asseldonk, Mariano Janiszewski, Protásio Lemos da Luz, Robert C.H. Scheffer
Publikováno v:
Free Radical Biology and Medicine. 29:889-899
Vascular NAD(P)H oxidase activity contributes to oxidative stress. Thiol oxidants inhibit leukocyte NADPH oxidase. To assess the role of reactive thiols on vascular oxidase, rabbit iliac/carotid artery homogenates were incubated with distinct thiol r