Výsledky vyhledávání - "Mariano J Levin"

Akademický článek

Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 111, Iss 6, Pp 365-371 (2016)

This study aimed to evaluate well-documented diagnostic antigens, named B13, 1F8 and JL7 recombinant proteins, as potential markers of seroconversion in treated chagasic patients. Prospective study, involving 203 patients treated with benznidazole, w

Externí odkaz: https://doaj.org/article/a838bcfe13b84d6d88d581bcde83470a

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Akademický článek

Proteins associated with SF3a60 in T. brucei.

Autor: Benson Nyambega, Claudia Helbig, Daniel K Masiga, Christine Clayton, Mariano J Levin

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91956 (2014)

Trypanosoma brucei relies on Spliced leader trans splicing to generate functional messenger RNAs. Trans splicing joins the specialized SL exon from the SL RNA to pre-mRNAs and is mediated by the trans-spliceosome, which is made up of small nuclear ri

Externí odkaz: https://doaj.org/article/edbb0c163e064887a91b3e1e49ee53c4

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Akademický článek

Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein.

Autor: Maximiliano Juri Ayub, Benson Nyambega, Leandro Simonetti, Tomas Duffy, Silvia A Longhi, Karina A Gómez, Johan Hoebeke, Mariano J Levin, Cristian R Smulski

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36233 (2012)

The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of th

Externí odkaz: https://doaj.org/article/868a09413ac44ebf9c52176ad53a898d

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Akademický článek

Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2β protein: implications in cross-reactivity.

Autor: Juan Carlos Pizarro, Ginette Boulot, Graham A Bentley, Karina A Gómez, Johan Hoebeke, Mireille Hontebeyrie, Mariano J Levin, Cristian R Smulski

Publikováno v: PLoS Neglected Tropical Diseases, Vol 5, Iss 11, p e1375 (2011)

Patients with Chronic Chagas' Heart Disease possess high levels of antibodies against the carboxyl-terminal end of the ribosomal P2ß protein of Trypanosoma cruzi (TcP2ß). These antibodies, as well as the murine monoclonal antibody (mAb) 17.2, recog

Externí odkaz: https://doaj.org/article/6e608724de6844cdae7c66dd5579fbb0

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Akademický článek

Parasite Genome Projects and the Trypanosoma cruzi Genome Initiative

Autor: Wim Degrave, Mariano J Levin, José Franco da Silveira, Carlos M Morel

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 92, Iss 6, p 859 (1997)

Since the start of the human genome project, a great number of genome projects on other "model" organism have been initiated, some of them already completed. Several initiatives have also been started on parasite genomes, mainly through support from

Externí odkaz: https://doaj.org/article/0cb58f779ab34a3a8d7f6c4efe258896

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Akademický článek

The Trypanosoma cruzi Genome Project: Nuclear Karyotype and Gene Mapping of Clone CL Brener

Autor: Marcia RM Santos, Maria I Cano, Alejandro Schijman, Hernan Lorenzi, Martin Vázquez, Mariano J Levin, José Luis Ramirez, Adeílton Brandão, Wim M Degrave, José Franco da Silveira

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 92, Iss 6, p 821 (1997)

By using improved pulsed field gel electrophoresis conditions, the molecular karyotype of the reference clone CL Brener selected for Trypanosoma cruzi genome project was established. A total of 20 uniform chromosomal bands ranging in size from 0.45 t

Externí odkaz: https://doaj.org/article/4348fc678cfd4c2c844f5885c57bbf61

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Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina

Publikováno v: Memórias do Instituto Oswaldo Cruz., Vol 111, Iss 6, Pp 365-371 (2016)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Paediatrics Publications
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz, Volume: 111, Issue: 6, Pages: 365-371, Published: 24 MAY 2016

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6655021ff5fbd8b70a389b7f9d62b1d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600365&lng=en&tlng=en

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Antibodies against the Trypanosoma cruzi ribosomal P proteins induce apoptosis in HL-1 cardiac cells

Autor: Ville Kytö, Pekka Saukko, Laura Mónica Tasso, Hernán García Rivello, Silvia Andrea Longhi, Gabriela V. Levy, Mariano J. Levin, Karina A. Gómez

Publikováno v: International Journal for Parasitology. 41:635-644

High levels of antibodies (Abs) against the C-terminal end of the Trypanosoma cruzi ribosomal P2β protein, defined by the R13 peptide, are detected in sera from patients with chronic Chagas heart disease (cChHD). These Abs can cross-react with the �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fb9ef6f774e5dc7631bb47a5620866
https://doi.org/10.1016/j.ijpara.2010.12.010

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Molecular Identification ofTrypanosoma cruziDiscrete Typing Units in End‐Stage Chronic Chagas Heart Disease and Reactivation after Heart Transplantation

Autor: Juan M. Burgos, Carolina Cura, Liliana E. Favaloro, Alejandro G. Schijman, Roberto R. Favaloro, Rubén P. Laguens, Raul Horacio Lucero, Carlos Vigliano, Marikena G. Risso, María Susana Leguizamón, Tomás Duffy, Mariano J. Levin, Margarita Bisio, Mirta Diez, Betina Brusses

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

One hundred years after the discovery of Chagas disease, it remains a major neglected tropical disease. Chronic Chagas heart disease is the most severe manifestation. Heart trasplantation is the proper treatment for end-stage heart failure. T. cruzi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce2c2ebdf10920e945469d8f7abb2b8
https://doi.org/10.1086/655680

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Cardiomyogenic differentiation of human bone marrow mesenchymal cells: Role of cardiac extract from neonatal rat cardiomyocytes

Autor: H. García Rivello, Erica Leonor Hofer, A. Bayes-Genis, Norma Alejandra Chasseing, Leonardo Feldman, Vivian Labovsky, Mariano J. Levin, A. Hernando Insúa, V. Fernández Vallone

Publikováno v: Differentiation. 79:93-101

Bone marrow mesenchymal stromal cells (BM-MSCs) with regenerative potential have been identified in heart. Whether these cells become new cardiac lineage cells by phenomena of transdifferentiation or fusion is also being investigated. Although, these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22568f0a22a35d34d83ff57aaf675b18
https://doi.org/10.1016/j.diff.2009.10.001

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