Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mariano A Ostuni"'
Autor:
Leeyah Issop, Mariano A Ostuni, Sunghoon Lee, Mireille Laforge, Gabriel Péranzi, Pierre Rustin, Jean-François Benoist, Jérome Estaquier, Vassilios Papadopoulos, Jean-Jacques Lacapère
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152919 (2016)
UNLABELLED:Chronic inflammation of the gastrointestinal tract increasing the risk of cancer has been described to be linked to the high expression of the mitochondrial translocator protein (18 kDa; TSPO). Accordingly, TSPO drug ligands have been show
Externí odkaz:
https://doaj.org/article/664bf669013d4244b481a8ec31acb30a
Autor:
Florencia Orrico, Sandrine Laurance, Ana C. Lopez, Sophie D. Lefevre, Leonor Thomson, Matias N. Möller, Mariano A. Ostuni
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1262 (2023)
Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that affect the structure, function, or production of red blood cells (RBCs). These disorders can lead to various clinical manifestations, including anemia, hemolysis,
Externí odkaz:
https://doaj.org/article/6b020c8550ec4a36ab03313ead6c3b1a
Autor:
Alice Dussouchaud, Julieta Jacob, Charles Secq, Jean-Marc Verbavatz, Martina Moras, Jérôme Larghero, Claudio M. Fader, Mariano A. Ostuni, Sophie D. Lefevre
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Throughout mammal erythroid differentiation, erythroblasts undergo enucleation and organelle clearance becoming mature red blood cell. Organelles are cleared by autophagic pathways non-specifically targeting organelles and cytosolic content or by spe
Externí odkaz:
https://doaj.org/article/f781ec2a10da4773bc6aeb46afa7c173
Autor:
Martina Moras, Claude Hattab, Pedro Gonzalez-Menendez, Claudio M. Fader, Michael Dussiot, Jerome Larghero, Caroline Le Van Kim, Sandrina Kinet, Naomi Taylor, Sophie D. Lefevre, Mariano A. Ostuni
Publikováno v:
Haematologica, Vol 107, Iss 1 (2021)
Erythroblast maturation in mammals is dependent on organelle clearance throughout terminal erythropoiesis. We studied the role of the outer mitochondrial membrane protein voltage-dependent anion channel-1 (VDAC1) in human terminal erythropoiesis. We
Externí odkaz:
https://doaj.org/article/4cedd1eb7aa44491a81e50206e22b882
Autor:
Sarah Rougé, Sandrine Genetet, Maria Florencia Leal Denis, Michael Dussiot, Pablo Julio Schwarzbaum, Mariano Anibal Ostuni, Isabelle Mouro-Chanteloup
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9401
Pannexin 1 (PANX1) was proposed to drive ATP release from red blood cells (RBCs) in response to stress conditions. Stomatin, a membrane protein regulating mechanosensitive channels, has been proposed to modulate PANX1 activity in non-erythroid cells.
Autor:
Mariano A. Ostuni, Julie Guellec, Patricia Hermand, Pauline Durand, Christophe Combadière, Frédéric Pincet, Philippe Deterre
Publikováno v:
Biology Open, Vol 3, Iss 12, Pp 1173-1182 (2014)
The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with structural analysis
Externí odkaz:
https://doaj.org/article/043fce7c655a401abb7b6253bbac284c
Autor:
Cora L. Alvarez, Arnaud Chêne, Jean-Philippe Semblat, Benoît Gamain, Claudine Lapouméroulie, Claudio M. Fader, Claude Hattab, Jean Sévigny, María Florencia Leal Denis, Natalia Lauri, Mariano A. Ostuni, Pablo J. Schwarzbaum
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1864(10)
Plasmodium falciparum, a dangerous parasitic agent causing malaria, invades human red blood cells (RBCs), causing hemolysis and microvascular obstruction. These and other pathological processes of malaria patients are due to metabolic and structural
Autor:
Nicolas A. Saffioti, Natalia Lauri, Lucia Cané, Rodolfo Gonzalez-Lebrero, Karina Alleva, Isabelle Mouro-Chanteloup, Mariano A. Ostuni, Vanesa Herlax, Pablo Julio Schwarzbaum
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 872
International Journal of Molecular Sciences, Vol 23, Iss 872, p 872 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2022, 23 (2), pp.872. ⟨10.3390/ijms23020872⟩
International Journal of Molecular Sciences, Vol 23, Iss 872, p 872 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2022, 23 (2), pp.872. ⟨10.3390/ijms23020872⟩
α-hemolysin (HlyA) of E. coli binds irreversibly to human erythrocytes and induces cell swelling, ultimately leading to hemolysis. We characterized the mechanism involved in water transport induced by HlyA and analyzed how swelling and hemolysis mig
Autor:
Alice, Dussouchaud, Julieta, Jacob, Charles, Secq, Jean-Marc, Verbavatz, Martina, Moras, Jérôme, Larghero, Claudio M, Fader, Mariano A, Ostuni, Sophie D, Lefevre
Publikováno v:
Frontiers in physiology. 12
Throughout mammal erythroid differentiation, erythroblasts undergo enucleation and organelle clearance becoming mature red blood cell. Organelles are cleared by autophagic pathways non-specifically targeting organelles and cytosolic content or by spe
Autor:
Sophie D. Lefevre, Mariano A. Ostuni, Claude Hattab, Vincent Jullien, Thibaud Lefebvre, Martina Moras, Suella Martino, Marie-Hélène Odièvre, Caroline Le Van Kim, Laurent Gouya, Jean-Benoît Arlet
Publikováno v:
British journal of haematologyReferences. 193(5)
Sickle cell disease (SCD) is characterised by chronic haemolysis and oxidative stress. Herein, we investigated 30 SCD patients and found 40% with elevated mitochondria levels (SS-mito+ ) in their mature red blood cells, while 60% exhibit similar mito