Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Mariannina Impicciatore"'
Autor:
Renato Bruni, Elisabetta Barocelli, Milena Chiavarini, Mariannina Impicciatore, Alberto Bianchi, Vigilio Ballabeni, Massimiliano Tognolini
Publikováno v:
Life Sciences. 78:1419-1432
Essential oils extracted from different plants (Anthemis nobilis L., Artemisia dracunculus L., Cannabis sativa L., Cupressus sempervirens L., Cymbopogon citratus (DC.) Stapf., Curcuma longa L., Foeniculum vulgare L., Hypericum perforatum L., Hyssopus
Autor:
Milena Chiavarini, Vigilio Ballabeni, Alberto Bianchi, Massimiliano Tognolini, Elisabetta Barocelli, Renato Bruni, Mariannina Impicciatore
Publikováno v:
Phytomedicine. 11:596-601
Lavender extracts are known to produce several mild effects at central and peripheral level. However, no studies are so far available about the potential effects of lavender essential oil on the hemostatic system. In this work, we demonstrated antipl
Autor:
Giorgio Gabella, Mariannina Impicciatore, Vigilio Ballabeni, Simona Bertoni, Elisabetta Barocelli, Paola Ghizzardi, M. L. Arcari, Costanza Lagrasta
Publikováno v:
Neurogastroenterology and Motility. 16:365-374
The present work aims at investigating the changes in motor responsiveness of rat intestine hypertrophied by chronic mechanical obstruction. Motor responses to pharmacological agents and electrical field stimulation (EFS) were studied in hypertrophic
Autor:
Elisabetta Barocelli, Francesca Magnanini, Mariannina Impicciatore, Francesco Calcina, Felice Liberatore, Vincenzo Carelli, Luigi Scipione, Vigilio Ballabeni, Gianfabio Giorgioni, Antonio Di Stefano
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:3765-3769
Two new GABA derivatives, 1 and 2, were synthesized and tested for their capacity to display CNS activity, which was assessed by determining the effects on the duration of pentobarbital-induced hypnosis in rats. Compound 1, peripherally injected, sig
Autor:
Simona Bertoni, Ezio Fasoli, Bryan L. Roth, Paul Ernsberger, Mariannina Impicciatore, Paola Conti, Carlo De Micheli, Elisabetta Barocelli, Marco De Amici, Vigilio Ballabeni
Publikováno v:
Il Farmaco. 58:739-748
A set of novel heterocyclic ligands (7a–9a, 7b–9b, and 9c) structurally related to oxotremorine 2 was designed, synthesized, and tested at muscarinic receptor subtypes. In the binding experiments at cloned hm1–5, the presence of the 2-methylimi
Autor:
Vigilio Ballabeni, Elisabetta Barocelli, Paola Vicini, Massimiliano Tognolini, Francesco Calcina, Mariannina Impicciatore
Publikováno v:
Pharmacological Research. 46:389-393
A series of 2-amino-benzo[d]isothiazol-3-one derivatives (1-8), previously described as in vitro potent antiaggregatory agents endowed with spasmolytic properties, was evaluated for in vitro antiplatelet activity in guinea-pig platelet rich plasma an
Autor:
Simona Bertoni, Elisabetta Barocelli, Vigilio Ballabeni, Mariannina Impicciatore, Marco De Amici
Publikováno v:
Life Sciences. 68:1775-1785
The central and peripheral effects of a series of Oxotremorine/Oxotremorine-M derivatives, previously characterized as muscarinic agonists in isolated preparations, were investigated in in vivo experiments. The molecules were tested for their antinoc
Autor:
Milena Chiavarini, Francesco Bondavalli, Angelo Ranise, Elisabetta Barocelli, Vigilio Ballabeni, Mariannina Impicciatore, Silvia Schenone, Simona Bertoni, Massimiliano Tognolini, Olga Bruno
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:629-636
The preparation and the pharmacological screening of novel anti-aggregatory/antiphlogistic polycyclic pyrimidine derivatives are described. The compounds were developed starting from bioactive 2-aminobenzopyranopyrimidine derivatives in order to asse
Autor:
Marco De Amici, Carlo De Micheli, Clelia Dallanoce, Vigilio Ballabeni, Simona Bertoni, Mariannina Impicciatore, Elisabetta Barocelli
Publikováno v:
Life Sciences. 67:717-723
Two subsets of tertiary amines (1a-6a) and methiodides (1b-6b) with a structural resemblance to oxotremorine and oxotremorine-M were tested at rabbit vas deferens (M1), guinea pig left atrium (M2), guinea pig ileum and urinary bladder (M3) muscarinic
Autor:
Vigilio Ballabeni, Valentina Zuliani, Marco Mor, Silvia Rivara, Mariannina Impicciatore, Federica Vacondio, Pier Vincenzo Plazzi, Elisabetta Barocelli, Claudia Silva, Giovanni Morini, Fabrizio Bordi
Publikováno v:
Il Farmaco. 55:27-34
New histamine H3-receptor antagonists were synthesised and tested on rat brain membranes and on electrically stimulated guinea-pig ileum. The new compounds have a central polar group represented by a 2-alkylimidazole or a 2-thioimidazoline nucleus. T