Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marianne Wauchop"'
Autor:
Zachary Laksman, Marianne Wauchop, Eric Lin, Stephanie Protze, Jeehoon Lee, Wallace Yang, Farzad Izaddoustdar, Sanam Shafaattalab, Lior Gepstein, Glen F. Tibbits, Gordon Keller, Peter H. Backx
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like card
Externí odkaz:
https://doaj.org/article/de4c7f423d3d4347aaa96056d0036cc4
Autor:
Jie Liu, Jason D Bayer, Roozbeh Aschar-Sobbi, Marianne Wauchop, Danna Spears, Michael Gollob, Edward J Vigmond, Robert Tsushima, Peter H Backx, Vijay S Chauhan
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197273 (2018)
BACKGROUND:The SCN5A mutation, P1332L, is linked to a malignant form of congenital long QT syndrome, type 3 (LQT3), and affected patients are highly responsive to the Na+ channel blocking drug, mexiletine. In contrast, A647D is an atypical SCN5A muta
Externí odkaz:
https://doaj.org/article/7a2d35b559e2465bbf94205a78d6d567
Autor:
Robert A. Rose, Stéphane Massé, John Asta, Patrick F.H. Lai, Mohammed Ali Azam, Marianne Wauchop, Christian Jons, Andreu Porta-Sánchez, Kumaraswamy Nanthakumar
Publikováno v:
Life sciences. 282
Aim An adverse side-effect of Liraglutide (LG), a Glucagon-Like Peptide 1 (GLP1)-analog commonly used in treatments for diabetes, is positive chronotropy. The goal of this study is to investigate on the mechanism of this drug-induced chronotropy and
Autor:
Jacob Burns, Farzad Izaddoustdar, Nazari Polidovitch, Xiaodong Gao, Robert Lakin, Peter H. Backx, Camilo Guzman, Marianne Wauchop, Sibao Yang
Publikováno v:
Journal of molecular and cellular cardiology. 129
Intense endurance exercise is linked to atrial fibrillation (AF). We established previously that interventions that simultaneously interfere with TNFα signaling, mediated via both the enzymatically liberated soluble and membrane-bound forms of TNFα
Autor:
Stephanie Protze, Zachary Laksman, Eric Lin, Farzad Izaddoustdar, Glen F. Tibbits, Lior Gepstein, Peter H. Backx, Sanam Shafaattalab, Wallace Yang, Gordon Keller, Marianne Wauchop, Jeehoon Lee
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like cardiomyocyte
Autor:
K. Nanthakumar, Stephanie Protze, Kelvin W. Chan Tung, Stéphane Massé, Naimeh Rafatian, Milica Radisic, Mark Gagliardi, Patrick F.H. Lai, Erika Yan Wang, Peter H. Backx, Gordon Keller, Marianne Wauchop
Publikováno v:
Journal of Molecular and Cellular Cardiology. 124:89-90