Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marianne Terndrup Pedersen"'
Autor:
Martti Maimets, Marianne Terndrup Pedersen, Jordi Guiu, Jes Dreier, Malte Thodberg, Yasuko Antoku, Pawel J. Schweiger, Leonor Rib, Raul Bardini Bressan, Yi Miao, K. Christopher Garcia, Albin Sandelin, Palle Serup, Kim B. Jensen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The small intestine forms via crosstalk between epithelial and mesenchymal cell compartments. Here, the authors show that a gradient of Wnt signalling along the anterior-posterior axis regulates Sonic Hedgehog which is required for correct formation
Externí odkaz:
https://doaj.org/article/f98ce2e90f0a4e679e2e55251af11038
Autor:
Fredrik Bergenheim, Jakob B. Seidelin, Marianne Terndrup Pedersen, Benjamin E. Mead, Kim B. Jensen, Jeffrey M. Karp, Ole Haagen Nielsen
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2019)
Abstract Background Intestinal stem cell transplantation has been shown to promote mucosal healing and to engender fully functional epithelium in experimental colitis. Hence, stem cell therapies may provide an innovative approach to accomplish mucosa
Externí odkaz:
https://doaj.org/article/9de7ea84ddd94ae6bdcac4f7ba09c93f
Autor:
Jenny Ostrop, Rosalie T. Zwiggelaar, Marianne Terndrup Pedersen, François Gerbe, Korbinian Bösl, Håvard T. Lindholm, Alberto Díez-Sánchez, Naveen Parmar, Silke Radetzki, Jens Peter von Kries, Philippe Jay, Kim B. Jensen, Cheryl Arrowsmith, Menno J. Oudhoff
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Intestinal organoids are an excellent model to study epithelial biology. Yet, the selection of analytical tools to accurately quantify heterogeneous organoid cultures remains limited. Here, we developed a semi-automated organoid screening method, whi
Externí odkaz:
https://doaj.org/article/aecc2679ef1d45a8875277b91cd0b5d7
Autor:
Laura M. Pikkupeura, Raul B. Bressan, Jordi Guiu, Yun Chen, Martti Maimets, Daniela Mayer, Pawel J. Schweiger, Stine L. Hansen, Grzegorz J. Maciag, Hjalte L. Larsen, Kadi Lõhmussaar, Marianne Terndrup Pedersen, Joji M. Yap Teves, Jette Bornholdt, Vladimir Benes, Albin Sandelin, Kim B. Jensen
During intestinal organogenesis, equipotent epithelial progenitors mature into phenotypically distinct stem cells that are responsible for life-long maintenance of the tissue. While the morphological changes associated with the transition are well-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5558980a4e13705126bbbdfd81999c28
https://doi.org/10.1101/2023.05.10.540120
https://doi.org/10.1101/2023.05.10.540120
Autor:
Marianne Terndrup Pedersen, Cheryl H. Arrowsmith, Menno J. Oudhoff, Naveen Parmar, Rosalie T. Zwiggelaar, Kim B. Jensen, Jenny Ostrop, Håvard T. Lindholm, Alberto Díez-Sánchez, François Gerbe, Silke Radetzki, Jens Peter von Kries, Philippe Jay, Korbinian Bösl
Publikováno v:
UnpayWall
ORCID
Microsoft Academic Graph
Institutional Repository for Molecular Medicine (MDC)
ORCID
Microsoft Academic Graph
Institutional Repository for Molecular Medicine (MDC)
The intestinal epithelium maintains an important barrier throughout life. It consists of several epithelial cell lineages that are derived from LGR5+ intestinal stem cells. Although epigenetic regulation of embryonic stem cell differentiation is well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c79676095561993d81e8e7721f09fb45
https://biorxiv.org/content/10.1101/2020.07.23.217414v1.full.pdf
https://biorxiv.org/content/10.1101/2020.07.23.217414v1.full.pdf
Autor:
Jeffrey M. Karp, Marianne Terndrup Pedersen, Benjamin E. Mead, Kim B. Jensen, Ole Haagen Nielsen, Fredrik Bergenheim, Jakob Benedict Seidelin
Publikováno v:
Stem Cell Research & Therapy
Bergenheim, F, Seidelin, J B, Pedersen, M T, Mead, B E, Jensen, K B, Karp, J M & Nielsen, O H 2019, ' Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy ', Stem Cell Research & Therapy, vol. 10, no. 1, 148, pp. 1-12 . https://doi.org/10.1186/s13287-019-1246-5
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2019)
Bergenheim, F, Seidelin, J B, Pedersen, M T, Mead, B E, Jensen, K B, Karp, J M & Nielsen, O H 2019, ' Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy ', Stem Cell Research & Therapy, vol. 10, no. 1, 148, pp. 1-12 . https://doi.org/10.1186/s13287-019-1246-5
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2019)
Background Intestinal stem cell transplantation has been shown to promote mucosal healing and to engender fully functional epithelium in experimental colitis. Hence, stem cell therapies may provide an innovative approach to accomplish mucosal healing
Autor:
Marianne S. Andersen, Soline Estrach, Kim B. Jensen, Kim E Boonekamp, Jens Vilstrup Johansen, Sarah Sendrup, Sabrina Pisano, Ditte L. Clement, Edouard Hannezo, Yasuko Antoku, Benjamin D. Simons, Marianne Terndrup Pedersen, Chloé C. Féral, Svetlana Ulyanchenko, Martti Maimets
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2019, 21 (8), pp.924-932. ⟨10.1038/s41556-019-0362-x⟩
Nature Cell Biology, Nature Publishing Group, 2019, 21 (8), pp.924-932. ⟨10.1038/s41556-019-0362-x⟩
The sebaceous gland (SG) is an essential component of the skin, and SG dysfunction is debilitating(1, 2). Yet, the cellular bases for its origin, development and subsequent maintenance remain poorly understood. Here, we apply large-scale quantitative
Autor:
Marianne Terndrup Pedersen, Susanne M. Kooistra, Anne Laugesen, Daniel G. Hayward, Kristian Helin, Jens Vilstrup Johansen, Aliaksandra Radzisheuskaya, Karl Agger, Jakob Nilsson
Publikováno v:
The EMBO Journal, 35(14), 1550-1564. Wiley
Chromatin-associated proteins are essential for the specification and maintenance of cell identity. They exert these functions through modulating and maintaining transcriptional patterns. To elucidate the functions of the Jmjd2 family of H3K9/H3K36 h
Autor:
Lauge Kellermann, Marianne Terndrup Pedersen, Stine Lund Hansen, Grzegorz Maciag, Lene Riis, Fredrik Bergenheim, Ole Haagen Nielsen, Kim B. Jensen
Publikováno v:
Gastroenterology. 158:S-1037
Autor:
Ivan Berest, Jesper Christensen, Lucía Simón-Carrasco, Marianne Terndrup Pedersen, Judith B. Zaugg, George S. Vassiliou, Kristian Helin, Sandra Kessler, Kasper D. Rasmussen, Koutarou Nishimura
Publikováno v:
Genome Research
Rasmussen, K D, Berest, I, Kessler, S, Nishimura, K, Simon-Carrasco, L, Vassiliou, G S, Pedersen, M T, Christensen, J, Zaugg, J & Helin, K 2019, ' TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells ', Genome Research, vol. 29, no. 4, pp. 564-575 . https://doi.org/10.1101/gr.239277.118
Rasmussen, K D, Berest, I, Kessler, S, Nishimura, K, Simon-Carrasco, L, Vassiliou, G S, Pedersen, M T, Christensen, J, Zaugg, J & Helin, K 2019, ' TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells ', Genome Research, vol. 29, no. 4, pp. 564-575 . https://doi.org/10.1101/gr.239277.118
The epigenetic regulator TET2 is frequently mutated in hematological diseases. Mutations have been shown to arise in hematopoietic stem cells early in disease development, lead to altered DNA methylation landscapes and to an increased risk of hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1369d45125c15cfc71fd641fa9c41ad7