Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marianne S. Evans"'
Autor:
Jean B. Dawidzik, Han-Chun DeFedericis, Edwin E. Budzinski, Harold C. Box, Douglas T. Bailey, Herbert Iijima, Kellee F. Greene, Harold G. Freund, Marianne S. Evans, Helen B. Patrzyc
Publikováno v:
Radiation Research. 167:146-151
UVC-radiation-induced DNA damage was measured in mouse fibroblast cells using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in conjunction with isotopically labeled internal standards. The thymine glycol and formamide lesions were assayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adfccee0cd5be2a49fdb65511fadaac
https://doi.org/10.1667/rr0693.1
https://doi.org/10.1667/rr0693.1
Autor:
Han-Chun DeFedericis, Jean B. Dawidzik, Edwin E. Budzinski, Marianne S. Evans, Helen B. Patrzyc, Kellee F. Greene, Michael J. Rajecki, Harold C. Box, Herbert Iijima
Publikováno v:
Radiation Research. 165:445-451
Singlet oxygen, hydrogen peroxide, hydroxyl radical and hydrogen peroxide are the reactive oxygen species (ROS) considered most responsible for producing oxidative stress in cells and organisms. Singlet oxygen interacts preferentially with guanine to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09684d616f893b84fe0ce93bb1d0791
https://doi.org/10.1667/rr3533.1
https://doi.org/10.1667/rr3533.1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1161:291-294
The hydrolysis by nuclease P1 of the 16 common deoxydinucleoside monophosphates was examined. The rates of hydrolysis of phosphodiester bond differ by more than two orders of magnitude; dinucleotide monophosphates of the type d(TpN) being most resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8521e3ce4478ff2d6652931ae5b4cbda
https://doi.org/10.1016/0167-4838(93)90227-i
https://doi.org/10.1016/0167-4838(93)90227-i
Autor:
Marianne S. Evans, Edwin E. Budzinski, Alexander E. Maccubbin, Harold G. Freund, Harold C. Box, Helen B. Patrzyc, John C. Wallace
Publikováno v:
International journal of radiation biology. 64(3)
Irradiation of the dinucleoside monophosphate d(GpT) in an oxygenated solution gives products characterized by damage on one or both guanine and thymine bases, the yields of which were proportional to radiation dose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c24e72a7c2a55901202689487b860db
https://pubmed.ncbi.nlm.nih.gov/8105004
https://pubmed.ncbi.nlm.nih.gov/8105004
Autor:
Edwin E. Budzinski, Marianne S. Evans, Helen B. Patrzyc, Noreen Ersing, Harold C. Box, Alexander E. Maccubbin
Publikováno v:
Free radical research communications. 18(1)
A prominent lesion in DNA exposed to oxidative free radicals results from the degradation of thymine leaving a formamido remnant. A 32P-postlabeling assay has been developed for the detection of the formamido lesion. The assay is based on the circums
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5a6606b9e2bfb366c221fc239c1c4f
https://pubmed.ncbi.nlm.nih.gov/8349146
https://pubmed.ncbi.nlm.nih.gov/8349146
Autor:
Harold C. Box, John C. Wallace, Alexander E. Maccubbin, Edwin E. Budzinski, Marianne S. Evans
Publikováno v:
International journal of radiation biology. 61(6)
Exposure of DNA oligomers to ionizing radiation in oxygenated solution reveals that the two lesions formed in highest yield are the 8-hydroxy modification of guanine and the formamido remnant of thymine. The effect of these lesions on the hydrolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d961325b112fa98c86465a1baf04fcf1
https://pubmed.ncbi.nlm.nih.gov/1351521
https://pubmed.ncbi.nlm.nih.gov/1351521
Autor:
Helen B. Patrzyc, Harold C. Box, Molly Kulesz-Martin, Joseph Przybyszewski, Marianne S. Evans, Alexander E. Maccubbin, Edwin E. Budzinski
Publikováno v:
Carcinogenesis. 16:1659-1660
A DNA lesion which results from the breakdown of a pyrimidine base leaving a formamido remnant has been associated with oxidative stress. This lesion is shown to be produced in keratinocytes irradiated in culture with UVB light. The amount of formami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cadad3e9f0c020ad040ba5645c0835
https://doi.org/10.1093/carcin/16.7.1659
https://doi.org/10.1093/carcin/16.7.1659
Autor:
Edwin E. Budzinski, Jason S. Gobey, Harold C. Box, John C. Wallace, Jean D. Dawidzik, Marianne S. Evans
Publikováno v:
Radiation Research. 145:641
A new type of tandem base lesion has been observed in d(CpGpTpA) X-irradiated in aqueous solution. The lesion is attributed to the formation of a covalent bond between the C8 carbon atom of guanine and the methyl carbon atom of thymine. This tandem b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc8b719a8acf050635119fcc9ce7f0c4
https://doi.org/10.2307/3579285
https://doi.org/10.2307/3579285
Autor:
Edwin E. Budzinski, Alexander E. Maccubbin, Molly Kulesz-Martin, Marianne S. Evans, Harold C. Box
Publikováno v:
Radiation Research. 132:288
The dinucleoside monophosphates d(TpG), d(TpC), and d(TpT) were X-irradiated in oxygenated solution. In each case the modification of the dinucleoside in which the thymine base is degraded to a formamido remnant was observed as a principal product. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320531526845156ae2405c0c6ac23447
https://doi.org/10.2307/3578236
https://doi.org/10.2307/3578236
Autor:
Alexander E. Maccubbin, Chitta R. Paul, Harold C. Box, Marianne S. Evans, Edwin E. Budzinski, Joseph Przybyszewski
Publikováno v:
Radiation Research. 126:21
Dinucleoside monophosphates in which the 5' nucleoside contained a radiation-modified base were tested as substrates to bovine spleen phosphodiesterase (SPD) and snake venom phosphodiesterase. The radiation-modified bases included thymine glycols, 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf109b552fe7f2a88382dd59331126e7
https://doi.org/10.2307/3578166
https://doi.org/10.2307/3578166