Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marianne Rueher"'
Autor:
Georg Jaeschke, Urs Niederhauser, Beatrice David, Eric Vieira, Will Spooren, Martin Kuratli, Jens-Uwe Peters, Michael Honer, Wolfgang Guba, Thomas Hartung, Daniel Tännler, Christoph Funk, Nadia Bitter-Stoll, Porter Richard Hugh Phillip, Bernd Büttelmann, Daniel Rueher, Paul Spurr, Jörg Huwyler, Nicole Clemann, Eric Prinssen, Joseph G. Wettstein, Axel Pähler, Simona M. Ceccarelli, Patrick Boissin, Theodor Stoll, Antonio Ricci, Jürgen Wichmann, Ann Petersen, Manfred Schneider, Marianne Rueher, Edilio Borroni, Sabine Kolczewski, Anthony Harrison, Lothar Lindemann
Publikováno v:
Journal of Medicinal Chemistry. 58:1358-1371
Negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGlu5) have potential for the treatment of psychiatric diseases including depression, fragile X syndrome (FXS), anxiety, obsessive-compulsive disorders, and levodopa induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f629d43eba9d48337f793d5244811596
https://doi.org/10.1021/jm501642c
https://doi.org/10.1021/jm501642c
Autor:
Luca Gobbi, Sandra Steiner, Marianne Rueher, Sara Belli, Robert F. Dannals, Daniel P. Holt, Dean F. Wong, Dieter Muri, Edilio Borroni, Andreas Koblet, Thomas Hartung, Henner Knust, William B. Mathews, Isabella Erbsmehl, Sandra Grall-Ulsemer, Heather Valentine, Hayden T. Ravert, Hiroto Kuwabara, Michael Honer, Christian Czech, Martin R. Edelmann, Matthias Körner
Publikováno v:
Journal of medicinal chemistry. 60(17)
Aggregates of tau and beta amyloid (Aβ) plaques constitute the histopathological hallmarks of Alzheimer’s disease and are prominent targets for novel therapeutics as well as for biomarkers for diagnostic in vivo imaging. In recent years much atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce01b52f118b9c3701a53264ea7cbca1
https://pubmed.ncbi.nlm.nih.gov/28654263
https://pubmed.ncbi.nlm.nih.gov/28654263
Autor:
Martin Binder, Will Spooren, Simona M. Ceccarelli, Patrick Boissin, Steven P. Hanlon, Ernst Kupfer, Eric Prinssen, Andreas Stämpfli, Georg Jaeschke, Bernd Buettelmann, Iris Ruf, Jens-Uwe Peters, Eric Vieira, Sabine Kolczewski, Marianne Rueher, Porter Richard Hugh Phillip, Götz Schlotterbeck
Publikováno v:
ChemMedChem. 3:136-144
Detailed information on the metabolic fate of lead compounds can be a powerful tool for an informed approach to the stabilization of metabolically labile compounds in the lead optimization phase. The combination of high performance liquid chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c694b039de119ef8a1ee142de1820b2d
https://doi.org/10.1002/cmdc.200700203
https://doi.org/10.1002/cmdc.200700203