Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marianne Reist"'
Autor:
Sophie Martel, Marc-Etienne Castella, Fania Bajot, Giorgio Ottaviani, Bruno Bard, Yveline Henchoz, Bénédicte Gross Valloton, Marianne Reist, Pierre-Alain Carrupt
Publikováno v:
CHIMIA, Vol 59, Iss 6 (2005)
Physicochemical and pharmacokinetic profiling of new chemical entities (NCEs) allows the rapid identification and elimination of compounds with properties not suitable for further development as drug candidates. Among the complex panel of theoretical
Externí odkaz:
https://doaj.org/article/3649bf10f7054b048839f86a39867627
Autor:
Laura Novaroli, Antoine Daina, Francesca Bertolini, Saviana Di Giovanni, Juan Bravo, Marianne Reist, Pierre-Alain Carrupt
Publikováno v:
CHIMIA, Vol 59, Iss 6 (2005)
Aging related neurodegenerative disorders such as Parkinson disease (PD) and Alzheimer's disease (AD) are the result of multiple pathophysiological pathways that contribute to the neurodegenerative cascade. Hence, multifunctional drug candidates able
Externí odkaz:
https://doaj.org/article/e36e8b1308f14fbfb4ba56889c9275dc
Publikováno v:
CHIMIA, Vol 59, Iss 6 (2005)
Successful drug research depends on adequate links between therapeutic benefits for the treatment of a disease, pertinent biological targets and suitable chemical compounds. The pharmacochemistry group at EPGL is active in the development of virtual
Externí odkaz:
https://doaj.org/article/54eb1845013e438ea11659fff8b8aa3f
Autor:
Bernard Testa, Giulia Caron, Patrizia Crivori, Sébastien Rey, Marianne Reist, Pierre Alain Carrupt
Publikováno v:
CHIMIA, Vol 54, Iss 11 (2000)
This minireview presents some recent work, mainly from the authors' laboratory, aimed at improving the interpretability and predictivity of structure-pharmacokinetic relationships. The first part of the text discusses the intermolecular forces and in
Externí odkaz:
https://doaj.org/article/0c9b8e36fd8d408bb95d45ded6d51613
Autor:
Pierre-Alain Carrupt, Kurt Hostettmann, Marianne Reist, Aurélie Urbain, Aline Borloz, Andrew Marston, Saviana Di Giovanni
Publikováno v:
European Journal of Pharmaceutical Sciences, Vol. 33, No 2 (2008) pp. 109-19
Acetylcholinesterase inhibitors (AChEI) are currently still the best available pharmacotherapy for Alzheimer patients. Successful screening for new AChEI relies on effective and fast assays. Two colorimetric screening assays frequently used to search
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98b68c001ac0ebfc64bf0f393d1fdc6
https://doi.org/10.1016/j.ejps.2007.10.004
https://doi.org/10.1016/j.ejps.2007.10.004
Autor:
Marko K. Ivancevic, Catherine M. Pastor, Sibylle Pochon, Joachim M. Mayer, François Terrier, Corinne Planchamp, Jean-Paul Vallée, Marianne Reist
Publikováno v:
Biotechnology and Bioengineering. 85:656-665
The aim of our study was to develop a magnetic resonance (MR)-compatible in vitro model containing freshly isolated rat hepatocytes to study the transport of hepatobiliary contrast agents (CA) by MR imaging (MRI). We set up a perfusion system includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0d3ed5800ef944f1b315792d28c740
https://doi.org/10.1002/bit.20017
https://doi.org/10.1002/bit.20017
Autor:
Georgette Plemper van Balen, Bernard Testa, Catherine a Marca Martinet, Géraldine Bouchard, Giulia Caron, Marianne Reist, Roberta Fruttero, Pierre-Alain Carrupt, Alberto Gasco
Publikováno v:
Medicinal Research Reviews, Vol. 24, No 3 (2004) pp. 299-324
This review discusses liposome/water lipophilicity in terms of the structure of liposomes, experimental methods, and information content. In a first part, the structural properties of the hydrophobic core and polar surface of liposomes are examined i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3a08344f2e9e25c9292f0195ce310b
https://doi.org/10.1002/med.10063
https://doi.org/10.1002/med.10063
Autor:
Corinne, Planchamp, Marko K, Ivancevic, Catherine M, Pastor, Jean-Paul, Vallée, Sibylle, Pochon, François, Terrier, Joachim M, Mayer, Marianne, Reist
Publikováno v:
Biotechnology and bioengineering
Biotechnology and Bioengineering, Vol. 85, No 6 (2004) pp. 656-65
Biotechnology and Bioengineering, Vol. 85, No 6 (2004) pp. 656-65
The aim of our study was to develop a magnetic resonance (MR)-compatible in vitro model containing freshly isolated rat hepatocytes to study the transport of hepatobiliary contrast agents (CA) by MR imaging (MRI). We set up a perfusion system includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9e7edc4ba1e70792f9527698d3aff4f8
Publikováno v:
Journal of Neurochemistry. 71:2431-2438
Sulphite is widely used as a preservative and antioxidant in foods, beverages, and pharmaceuticals. Endogenous sulphite is generated during the normal metabolism of sulphur-containing amino acids, and alterations in sulphur amino acid metabolism occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0b931b85bd27dd4d57bc64ab3d01cc
https://doi.org/10.1046/j.1471-4159.1998.71062431.x
https://doi.org/10.1046/j.1471-4159.1998.71062431.x
Autor:
Bernard Testa, Richard H. Guy, Pierre-Alain Carrupt, Annette L. Bunge, Marianne Reist, Sebastien Rey, Sandrine Geinoz, Gilles Boss
Publikováno v:
Pharmaceutical Research. 19:1622-1629
Purpose. The purpose of this work was to assess the molecular properties that influence solute permeation across silicone membranes and to compare the results with transport across human skin. Methods. The permeability coefficients (log K p) of a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089df50eb29883c0e5d54da3d92c7108
https://doi.org/10.1023/a:1020745026766
https://doi.org/10.1023/a:1020745026766