Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marianne Polunas"'
Autor:
Khea Wolff, Keyaara Robinson, Nanjoo Suh, Bozena Michniak-Kohn, Michael Goedken, Marianne Polunas, Ilya Raskin
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 4, Pp 100479- (2023)
Background: Moringa (Moringa oleifera Lam.) seed extract (MSE) and its primary bioactive compound, moringa isothiocyanate-1(MIC-1), mitigate inflammation, oxidative stress, diabetes, and cancer in the in vivo rodent models following oral application.
Externí odkaz:
https://doaj.org/article/8d877aa15c8a4824aa5e37df1dfbb8af
Autor:
Chelsea M Cary, Talia N Seymore, Dilpreet Singh, Kinal N Vayas, Michael J Goedken, Samantha Adams, Marianne Polunas, Vasanthi R Sunil, Debra L Laskin, Philip Demokritou, Phoebe A Stapleton
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Exposure to micro- and nanoplastic particles (MNPs) in humans is being identified in both the indoor and outdoor environment. Detection of these materials in the air has made inhalation exposure to MNPs a major cause for concern.
Externí odkaz:
https://doaj.org/article/42bbe059b984466a9ccc55920b70624f
Autor:
Chelsea M. Cary, Glen M. DeLoid, Zhenning Yang, Dimitrios Bitounis, Marianne Polunas, Michael J. Goedken, Brian Buckley, Byron Cheatham, Phoebe A. Stapleton, Philip Demokritou
Publikováno v:
Nanomaterials, Vol 13, Iss 4, p 720 (2023)
Recent studies in experimental animals found that oral exposure to micro- and nano-plastics (MNPs) during pregnancy had multiple adverse effects on outcomes and progeny, although no study has yet identified the translocation of ingested MNPs to the p
Externí odkaz:
https://doaj.org/article/c33eed4e9afc480ba6b4c39a8f5707ec
Autor:
Anastasia Diolintzi, YinXiu Zhou, Susan K. Fried, Marianne Polunas, Labros S. Sidossis, Judith Storch
Publikováno v:
The FASEB Journal. 36
Autor:
Moumita Dutta, Sora Choi, Jeffrey O. Asubonteng, Julia Yue Cui, Frank J. Gonzalez, Maxwell A. Gyamfi, Sarah Kim, Marianne Polunas, Michael Goedken
Publikováno v:
Biochem Pharmacol
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease due to the current epidemics of obesity and diabetes. The pregnane X receptor (PXR) is a xenobiotic-sensing nuclear receptor known for trans-activating liver genes i
Autor:
Chen Yang, Hatem E. Sabaawy, Marianne Polunas, Ki-Bum Lee, Shawn A. Chester, Jeffrey Luo, Howon Lee, Nikola Bosnjak, Michelle Chadwick, Sy-Tsong Dean Chueng
Publikováno v:
Adv Mater
Three-dimensional (3D) cell cultures are rapidly emerging as a promising tool to model various human physiologies and pathologies by closely recapitulating key characteristics and functions of in vivo microenvironment. While high-throughput 3D cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7584d66e69b796133fee639c9a1aaee3
https://europepmc.org/articles/PMC7603422/
https://europepmc.org/articles/PMC7603422/
Autor:
Angela L. Slitt, Jitka Bečanová, Seyed Mohamad Sadegh Modaresi, Marisa Pfohl, Michael Goedken, Juliana Agudelo, Wei Wei, Marianne Polunas, Emily Marques, Emily M. Kaye
Publikováno v:
Toxicology
Per- and polyfluoroalkyl substances (PFAS) are a family of chemicals that are ubiquitous in the environment. Some of these chemicals, such as perfluorooctanesulfonic acid (PFOS), perfluorohexanesulfonate (PFHxS) and perfluorooctanoic acid (PFOA), are
Autor:
Srujana Golla, Changtao Jiang, Cen Xie, Naoki Tanaka, Frank J. Gonzalez, Kristopher W. Krausz, Shogo Takahashi, Yusuke Masuo, Marianne Polunas, Blair C. Weig, Tatsuki Fukami
Publikováno v:
Toxicological Sciences. 158:334-346
Hepatotoxicity is of major concern for humans exposed to industrial chemicals and drugs. Disruption of farnesoid X receptor (FXR), a master regulator of bile acid (BA) metabolism, enhanced the sensitivity to liver injury in mice after toxicant exposu
Autor:
Arash Hatefi, Marianne Polunas, Niket Patel, Pedro Louro, Alireza Nomani, Obeid M. Malekshah, Siddik Sarkar, Michael Goedken, Parisa Javidian
Publikováno v:
J Control Release
The objective of this study was to develop a stem cell-based system for targeted suicide gene therapy of recurrent, metastatic, and unresectable ovarian cancer. Malignant cells were obtained from the ascites of a patient with advanced recurrent epith
Publikováno v:
Cellular and Molecular Bioengineering
Introduction We previously demonstrated that insulin secreting cells (ISCs) accelerate healing of chronic wounds, and it is known that mesenchymal stem cells (MSCs) also accelerate wound healing. Here, we report that the combination of both cell type