Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Marianne M, Lee"'
Autor:
Wenxiu Zhang, Zaofeng Yang, Jiale Zheng, Kaili Fu, Jack Ho Wong, Yunbi Ni, Tzi Bun Ng, Chi Hin Cho, Michael K. Chan, Marianne M. Lee
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Helicobacter pylori (H. pylori) causes infection in the stomach and is a major factor for gastric carcinogenesis. The application of antimicrobial peptides (AMPs) as an alternative treatment to traditional antibiotics is limited by their fac
Externí odkaz:
https://doaj.org/article/20d543b4651740d89077bc1f831a2647
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Although immune checkpoint inhibitors (ICIs) have been shown to yield promising therapeutic outcomes in a small subset of patients with triple negative breast cancer (TNBC), the majority of patients either do not respond or subsequently de
Externí odkaz:
https://doaj.org/article/5dc74c03c0024904801f2397e4b72253
Publikováno v:
Toxins, Vol 14, Iss 12, p 823 (2022)
The crystal protein Cry5B, a pore-forming protein produced by the soil bacterium Bacillus thuringiensis, has been demonstrated to have excellent anthelmintic activity. While a previous structure of the three-domain core region of Cry5B(112–698) had
Externí odkaz:
https://doaj.org/article/3297a130007e4b1fac42f837a6b409b9
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background We have recently developed a one-step, genetically encoded immobilization approach based on fusion of a target enzyme to the self-crystallizing protein Cry3Aa, followed by direct production and isolation of the fusion crystals fro
Externí odkaz:
https://doaj.org/article/6c24578971ce48e588d19c5f1fbbc204
Autor:
Jingxuan Tai, Lin Wang, Wai Shan Chan, Jiahui Cheng, Yuk Hei Chan, Marianne M. Lee, Michael K. Chan
Publikováno v:
Journal of the American Chemical Society. 145:10249-10258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee82cdb8facce92fd6faa487390ae4f1
https://doi.org/10.1021/jacs.3c01291
https://doi.org/10.1021/jacs.3c01291
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract The use of immobilized enzymes as biocatalysts has great potential to improve the efficiency and environmental sustainability of many industrial processes. Here, we report a novel approach that allows for the direct production of a highly ac
Externí odkaz:
https://doaj.org/article/c38eb2df5dcc40cdb2c520c9462177cd
Publikováno v:
Acta Biomaterialia. 135:582-592
The tumor suppressor p16 protein is an endogenous CDK4/6 inhibitor. Inactivation of its encoding gene is found in nearly half of human cancers. Restoration of p16 function via adenovirus-based gene delivery has been shown to be effective in suppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d10a563f1eff2fafb73bbdb5dc2573
https://doi.org/10.1016/j.actbio.2021.08.054
https://doi.org/10.1016/j.actbio.2021.08.054
Publikováno v:
Crystals, Vol 9, Iss 6, p 287 (2019)
Cry proteins have been the subject of intense research due to their ability to form crystals naturally in Bacillus thuringiensis (Bt). In this research we developed a new strategy that allows for the removal of cadmium and chromium from wastewater by
Externí odkaz:
https://doaj.org/article/75938d12502e4857b51bf7b45caf8cd5
Publikováno v:
Journal of the American Chemical Society. 142:9879-9883
Cry3Aa is a protein that forms crystals naturally in the bacterium Bacillus thuringiensis. Here we report that coexpression of Cry3Aa and a Proteus mirabilis lipase without recombinant fusion results in the efficient passive entrapment of the lipase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ce96982fcd0d9ba71f01d29db903326
https://doi.org/10.1021/jacs.9b13462
https://doi.org/10.1021/jacs.9b13462
Autor:
Manoj S Nair, Marianne M Lee, Astrid Bonnegarde-Bernard, Julie A Wallace, Donald H Dean, Michael C Ostrowski, Richard W Burry, Prosper N Boyaka, Michael K Chan
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127669 (2015)
Protein delivery platforms are important tools in the development of novel protein therapeutics and biotechnologies. We have developed a new class of protein delivery agent based on sub-micrometer-sized Cry3Aa protein crystals that naturally form wit
Externí odkaz:
https://doaj.org/article/478bc650b8b742feb4ba93b78b2255eb