Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marianne Lintz"'
Autor:
Alikhan B. Fidai, Byumsu Kim, Marianne Lintz, Sertac Kirnaz, Pravesh Gadjradj, Blake I. Boadi, Maho Koga, Ibrahim Hussain, Roger Härtl, Lawrence J. Bonassar
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Background Mechanical augmentation upon implantation is essential for the long‐term success of tissue‐engineered intervertebral discs (TE‐IVDs). Previous studies utilized stiffer materials to fabricate TE‐IVD support structures. Howe
Externí odkaz:
https://doaj.org/article/3b4f0ba4a7ca494697108185ba46c6a1
Autor:
Maho Koga, Byumsu Kim, Marianne Lintz, Sertaç Kirnaz, Jacob L. Goldberg, Ibrahim Hussain, Branden Medary, Kathleen N. Meyers, Suzanne A. Maher, Roger Härtl, Lawrence J. Bonassar
Publikováno v:
JOR Spine, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background Tissue‐engineered intervertebral disc (TE‐IVD) constructs are an attractive therapy for treating degenerative disc disease and have previously been investigated in vivo in both large and small animal models. The mechanical env
Externí odkaz:
https://doaj.org/article/8e28eb9a8ffa44948e9d41149b67f179
Autor:
Alikhan Fidai, Byumsu Kim, Marianne Lintz, Pravesh Gadjradj, Sertac Kirnaz, Blake Boadi, Ibrahim Hussain, Roger Hartl
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 21-21 (2024)
OBJECTIVES/GOALS: We evaluated the long-term success of tissue engineered intervertebral discs (TE-IVDs) cultured in flexible (FPLA) or stiff (PLA) support materials, hypothesizing that FPLA would maintain disc height and tissue hydration in the mini
Externí odkaz:
https://doaj.org/article/72059cec8292425e89c1ee4823fe8dd1
Publikováno v:
JOR Spine, Vol 5, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Diabetes has long been implicated as a major risk factor for intervertebral disc (IVD) degeneration, interfering with molecular signaling and matrix biochemistry, which ultimately aggravates the progression of the disease. Gluco
Externí odkaz:
https://doaj.org/article/93e3ac3a6956415f8760c7d5b8f7d564
Autor:
Sertac Kirnaz, Sunidhi Singh, Charisse Capadona, Marianne Lintz, Jacob L. Goldberg, Lynn B. McGrath, Branden Medary, Fabian Sommer, Lawrence J. Bonassar, Roger Härtl
Publikováno v:
World Neurosurgery. 157:282-299
Low back pain is the leading cause of work absences and years lived with disability, and it is often associated with degenerative disc disease. In recent years, biological treatment approaches such as the use of growth factors, cell injections, annul
Autor:
Roger Härtl, Marianne Lintz, Charisse Capadona, Rachel Yerden, Branden Medary, Byumsu Kim, Lynn B. McGrath, Jacob L. Goldberg, Sertac Kirnaz, Fabian Sommer, Lawrence J. Bonassar
Publikováno v:
Int J Spine Surg
The human intervertebral disc (IVD) is a complex organ composed of fibrous and cartilaginous connective tissues, and it serves as a boundary between 2 adjacent vertebrae. It provides a limited range of motion in the torso as well as stability during
Publikováno v:
Nature Reviews Rheumatology. 14:393-403
Developing therapeutic molecules that target chondrocytes and locally produced inflammatory factors within arthritic cartilage is an active area of investigation. The extensive studies that have been conducted over the past 50 years have enabled the
Publikováno v:
Tissue Engineering Part B: Reviews. 24:179-190
Lower back pain, the leading cause of workplace absences and disability, is often attributed to intervertebral disc degeneration, in which nucleus pulposus (NP) herniates through lesions in the annulus fibrosus (AF) and impinges on the spinal cord an
Autor:
Lisa A. Fortier, Marianne Lintz
Publikováno v:
Operative Techniques in Sports Medicine. 28:150776
A natural reservoir of stem/progenitor cells exists in most tissues of the musculoskeletal system including cartilage, meniscus, ligament, tendon, bone, muscle, and the synovial membrane. These resident stem cells are important during development, bu
Metastasis is a dynamic process in which cancer cells navigate the tumor microenvironment, largely guided by external chemical and mechanical cues. Our current understanding of metastatic cell migration has relied primarily on studies of single cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50983db69312ac58f68cf8f936df68fc
https://europepmc.org/articles/PMC5395914/
https://europepmc.org/articles/PMC5395914/