Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marianne L. Ciavarella"'
Autor:
Erik W. Thompson, Ian G. Campbell, A. Connor, Wen Qiu, Robin L. Anderson, Louise H. Williams, C. Blancher, Christine S. F. Hooi, I. M. Revet, Marianne L. Ciavarella, Wayne A. Phillips
Publikováno v:
Oncogene. 25:3924-3933
Multiple lines of evidence have provided compelling evidence for the existence of a tumor suppressor gene (TSG) on chromosome 7q31.1. ST7 may be the target of this genetic instability but its designation as a TSG is controversial. In this study, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a68af9900e773f382352edeb691d892
https://doi.org/10.1038/sj.onc.1209418
https://doi.org/10.1038/sj.onc.1209418
Autor:
Richard B. Pearson, Briony E. Cristiano, Christine S. F. Hooi, Karen G. Montgomery, Sarah E. Russell, Marianne L. Ciavarella, Ian G. Campbell, Wayne A. Phillips, David Y.H. Choong
Publikováno v:
Cancer Research. 64:7678-7681
Phosphatidylinositol 3′-kinases are lipid kinases with important roles in neoplasia. Recently, a very high frequency of somatic mutations in PIK3CA has been reported among a large series of colorectal cancers. However, the relevance of PIK3CA mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6262ac08400cafb97d72280d42081d
https://doi.org/10.1158/0008-5472.can-04-2933
https://doi.org/10.1158/0008-5472.can-04-2933
Autor:
Chris Dow, Steven Rockman, Elizabeth Vincan, Wayne A. Phillips, Scott A. Currie, Robert J. Thomas, Marianne L. Ciavarella
Publikováno v:
Journal of Biological Chemistry. 276:45113-45119
Activation of beta-catenin/T cell factor (TCF) transcription as a result of mutations in the adenomatous polyposis coli (APC) and/or beta-catenin genes occurs in the majority of colon tumors. An increasing number of genes, including c-myc and cyclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3318ca52c1c1c8c1dcec59ba67b47ea
https://doi.org/10.1074/jbc.m107742200
https://doi.org/10.1074/jbc.m107742200
Autor:
David Y.H. Choong, Katherine Smith, Ian G. Campbell, Sarah E. Russell, Robert J. Thomas, Wayne A. Phillips, Richard B. Pearson, Marianne L. Ciavarella, Karen G. Montgomery
Publikováno v:
International Journal of Cancer. 118:2644-2646
Mutation of PIK3CA, the gene coding for the p110α catalytic subunit of phosphoinositide 3-kinase (PI3K), has been reported in a limited range of human tumors. We now report that PIK3CA is also mutated in esophageal tumors. Single-strand conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd325a3feddec1d7dfb88d4af513e0f8
https://doi.org/10.1002/ijc.21706
https://doi.org/10.1002/ijc.21706
Autor:
Adam Kowalczyk, Wayne A. Phillips, Cuong Duong, William K. Murray, Danielle M. Greenawalt, Robert J. Thomas, Garvesh Raskutti, Marianne L. Ciavarella
Publikováno v:
Annals of surgical oncology. 14(12)
The use of neoadjuvant therapy, in particular chemoradiotherapy (CRT), in the treatment of esophageal cancer (EC) remains controversial. The ability to predict treatment response in an individual EC patient would greatly aid therapeutic planning. Gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d56d7c7095f1a40bc2ad0a05e9cb54
https://pubmed.ncbi.nlm.nih.gov/17896157
https://pubmed.ncbi.nlm.nih.gov/17896157