Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Marianne L Jensen"'
Autor:
Amy Easton, Marianne L. Jensen, Congwei Wang, Peter H. Hagedorn, Yuwen Li, Michael Weed, Jere E. Meredith, Valerie Guss, Kelli Jones, Martin Gill, Carol Krause, Jeffrey M. Brown, Lisa Hunihan, Joanne Natale, Alda Fernandes, Yifeng Lu, Joe Polino, Mark Bookbinder, Greg Cadelina, Yulia Benitex, Ramola Sane, John Morrison, Dieter Drexler, Stephen E. Mercer, Charlotte Bon, Nikhil J. Pandya, Ravi Jagasia, Tai-Hsien Ou Yang, Tania Distler, Fiona Grüninger, Michael Meldgaard, Marco Terrigno, John E. Macor, Charles F. Albright, James Loy, Anja M. Hoeg, Richard E. Olson, Angela M. Cacace
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 625-642 (2022)
Tau is a microtubule-associated protein (MAPT, tau) implicated in the pathogenesis of tauopathies, a spectrum of neurodegenerative disorders characterized by accumulation of hyperphosphorylated, aggregated tau. Because tau pathology can be distinct a
Externí odkaz:
https://doaj.org/article/b93757f19dfa46c987c592a3e606bdbe
Autor:
Brian R. Anderson, Marianne L. Jensen, Peter H. Hagedorn, Sean C. Little, Richard E. Olson, Ron Ammar, Bernadette Kienzle, John Thompson, Ivar McDonald, Stephen Mercer, Jonas Vikesaa, Bettina Nordbo, Larry Iben, Yang Cao, Joanne Natale, Greg Dalton-Kay, Angela Cacace, Bo R. Hansen, Maj Hedtjärn, Troels Koch, Linda J. Bristow
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1290-1298 (2020)
Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibi
Externí odkaz:
https://doaj.org/article/ebaf673f331045b1903490834433fa8c
Autor:
Peter H, Hagedorn, Jeffrey M, Brown, Amy, Easton, Maria, Pierdomenico, Kelli, Jones, Richard E, Olson, Stephen E, Mercer, Dong, Li, James, Loy, Anja M, Høg, Marianne L, Jensen, Martin, Gill, Angela M, Cacace
Publikováno v:
Nucleic Acid Therapeutics. 32:151-162
Antisense oligonucleotides are a relatively new therapeutic modality and safety evaluation is still a developing area of research. We have observed that some oligonucleotides can produce acute, nonhybridization dependent, neurobehavioral side effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84306dc3fdd2daeba90224f662941fbf
https://doi.org/10.1089/nat.2021.0071
https://doi.org/10.1089/nat.2021.0071
Autor:
Rasmus Fromsejer, Marianne L. Jensen, Matthew O. Zacate, Victoria L. Karner, Vincent L. Pecoraro, Lars Hemmingsen
Publikováno v:
Fromsejer, R, Jensen, M L, Zacate, M O, Karner, V, Pecoraro, V L & Hemmingsen, L 2023, ' Molecular rotational correlation times and nanoviscosity determined by 111m Cd perturbed angular correlation (PAC) of γ-rays spectroscopy ', Chemistry: A European Journal, vol. 29, no. 9, e202203084 . https://doi.org/10.1002/chem.202203084
The nanoviscosity experienced by molecules in solution may be determined through measurement of the molecular rotational correlation time, τc, for example, by fluorescence and NMR spectroscopy. With this work, we apply PAC spectroscopy to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90e9c11cfed24b360361ba20265cfa6
https://doi.org/10.1002/chem.202203084
https://doi.org/10.1002/chem.202203084
Autor:
Marianna, Tosato, Mattia, Asti, Valerio, Di Marco, Marianne L, Jensen, Juliana, Schell, Thien Thanh, Dang, Ulli, Köster, Mikael, Jensen, Lars, Hemmingsen
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::449a4db299b50ee862fd9d86efc92b37
https://pubmed.ncbi.nlm.nih.gov/36283328
https://pubmed.ncbi.nlm.nih.gov/36283328
Autor:
Marianna Tosato, Mattia Asti, Valerio Di Marco, Marianne L. Jensen, Juliana Schell, Thien Thanh Dang, Ulli Köster, Mikael Jensen, Lars Hemmingsen
Publikováno v:
Tosato, M, Asti, M, Di Marco, V, Jensen, M L, Schell, J, Dang, T T, Koster, U, Jensen, M & Hemmingsen, L 2022, ' Towards in vivo applications of 111 Ag perturbed angular correlation of γ-rays (PAC) spectroscopy ', Applied Radiation and Isotopes, vol. 190, 110508 . https://doi.org/10.1016/j.apradiso.2022.110508
Tosato, M, Asti, M, Di Marco, V, Jensen, M L, Schell, J, Dang, T T, Köster, U, Jensen, M & Hemmingsen, L 2022, ' Towards in vivo applications of 111 Ag perturbed angular correlation of γ-rays (PAC) spectroscopy ', Applied Radiation and Isotopes, vol. 190, 110508 . https://doi.org/10.1016/j.apradiso.2022.110508
Tosato, M, Asti, M, Di Marco, V, Jensen, M L, Schell, J, Dang, T T, Köster, U, Jensen, M & Hemmingsen, L 2022, ' Towards in vivo applications of 111 Ag perturbed angular correlation of γ-rays (PAC) spectroscopy ', Applied Radiation and Isotopes, vol. 190, 110508 . https://doi.org/10.1016/j.apradiso.2022.110508
111Ag-perturbed angular correlation of γ-rays (PAC) spectroscopy provides information on the nuclear quadrupole interactions, and thereby on the local structure and dynamics of the silver ion binding site. Brownian rotational motion, i.e. rotational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c6ecb45e30d72ad6ec9bd2507af5d5
https://curis.ku.dk/ws/files/327056141/1_s2.0_S0969804322003931_main.pdf
https://curis.ku.dk/ws/files/327056141/1_s2.0_S0969804322003931_main.pdf
Autor:
Ria K. Balogh, Béla Gyurcsik, Mikael Jensen, Peter W. Thulstrup, Ulli Köster, Niels Johan Christensen, Marianne L. Jensen, Éva Hunyadi‐Gulyás, Lars Hemmingsen, Attila Jancsó
Publikováno v:
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Köster, U, Christensen, N J, Jensen, M L, Hunyadi-Gulyás, É, Hemmingsen, L & Jancsó, A 2022, ' Tying Up a Loose End : On the Role of the C-Terminal CCHHRAG Fragment of the Metalloregulator CueR ', ChemBioChem, vol. 23, no. 16, e202200290 . https://doi.org/10.1002/cbic.202200290
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Koester, U, Christensen, N J, Jensen, M L, Hunyadi-Gulyas, E, Hemmingsen, L & Jancso, A 2022, ' Tying Up a Loose End : On the Role of the C-Terminal CCHHRAG Fragment of the Metalloregulator CueR ', ChemBioChem, vol. 23, no. 16, 202200290 . https://doi.org/10.1002/cbic.202200290
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Koester, U, Christensen, N J, Jensen, M L, Hunyadi-Gulyas, E, Hemmingsen, L & Jancso, A 2022, ' Tying Up a Loose End : On the Role of the C-Terminal CCHHRAG Fragment of the Metalloregulator CueR ', ChemBioChem, vol. 23, no. 16, 202200290 . https://doi.org/10.1002/cbic.202200290
The transcriptional regulator CueR is activated by the binding of CuI, AgI, or AuI to two cysteinates in a near-linear fashion. The C-terminal CCHHRAG sequence in Escherichia coli CueR present potential additional metal binding ligands and here we ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6e74408ddfdb1383338cefccbfcb8c
https://orbit.dtu.dk/en/publications/6368e5c3-04de-46e9-b93c-38c71b9f0688
https://orbit.dtu.dk/en/publications/6368e5c3-04de-46e9-b93c-38c71b9f0688
Autor:
Amy Easton, Marianne L. Jensen, Congwei Wang, Peter H. Hagedorn, Yuwen Li, Michael Weed, Jere E. Meredith, Valerie Guss, Kelli Jones, Martin Gill, Carol Krause, Jeffrey M. Brown, Lisa Hunihan, Joanne Natale, Alda Fernandes, Yifeng Lu, Joe Polino, Mark Bookbinder, Greg Cadelina, Yulia Benitex, Ramola Sane, John Morrison, Dieter Drexler, Stephen E. Mercer, Charlotte Bon, Nikhil J. Pandya, Ravi Jagasia, Tai-Hsien Ou Yang, Tania Distler, Fiona Grüninger, Michael Meldgaard, Marco Terrigno, John E. Macor, Charles F. Albright, James Loy, Anja M. Hoeg, Richard E. Olson, Angela M. Cacace
Publikováno v:
Molecular therapy. Nucleic acids. 29
Tau is a microtubule-associated protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc4302dcff03d41215dd8c99c37d729
https://pubmed.ncbi.nlm.nih.gov/36090761
https://pubmed.ncbi.nlm.nih.gov/36090761
Autor:
Arnela Mehmedbasic, Egija Zole, Olav M. Andersen, Pernille Barkholt, Henrik Vorum, Marianne L Jensen, Jens R. Nyengaard, Margarita Melnikova Jørgensen, Ida E. Holm, Christian Bjerggaard Vaegter, Giulia Monti
Publikováno v:
Monti, G, Jensen, M L, Mehmedbasic, A, Jørgensen, M M, Holm, I E, Barkholt, P, Zole, E, Vægter, C B, Vorum, H, Nyengaard, J R & Andersen, O M 2020, ' SORLA Expression in Synaptic Plexiform Layers of Mouse Retina ', Molecular Neurobiology, vol. 57, no. 7, pp. 3106-3117 . https://doi.org/10.1007/s12035-020-01946-x
Sorting protein-related receptor containing LDLR class A repeats (SORLA; also known as LR11) exerts intraneuronal trafficking functions in the central nervous system. Recently, involvement of SORLA in retinogenesis was proposed, but no studies have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe0789fcfdd6965fa68137d5eb14b71
https://vbn.aau.dk/da/publications/f84839a6-e5f6-454c-a006-7be2237cadfc
https://vbn.aau.dk/da/publications/f84839a6-e5f6-454c-a006-7be2237cadfc
Autor:
Peter W. Thulstrup, Mikael Jensen, Ria K. Balogh, Frederik J. Mørch, Marianne L. Jensen, Niels Johan Christensen, Lars Hemmingsen, Attila Jancsó, Béla Gyurcsik, Ulli Köster
Publikováno v:
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Köster, U, Christensen, N J, Mørch, F J, Jensen, M L, Jancsó, A & Hemmingsen, L 2020, ' Flexibility of the CueR Metal Site Probed by Instantaneous Change of Element and Oxidation State from Ag I to Cd II ', Chemistry: A European Journal, vol. 26, no. 33, pp. 7451-7457 . https://doi.org/10.1002/chem.202000132
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Köster, U, Christensen, N J, Mørch, F J, Jensen, M L, Jancso, A & Hemmingsen, L 2020, ' Flexibility of the CueR Metal Site Probed by Instantaneous Change of Element and Oxidation State from Ag I to Cd II ', Chemistry-A European Journal, vol. 26, no. 33, pp. 7451-7457 . https://doi.org/10.1002/chem.202000132
Chemistry (Weinheim an Der Bergstrasse, Germany)
'Chemistry-A European Journal ', vol: 26, pages: 7451-7457 (2020)
Balogh, R K, Gyurcsik, B, Jensen, M, Thulstrup, P W, Köster, U, Christensen, N J, Mørch, F J, Jensen, M L, Jancso, A & Hemmingsen, L 2020, ' Flexibility of the CueR Metal Site Probed by Instantaneous Change of Element and Oxidation State from Ag I to Cd II ', Chemistry-A European Journal, vol. 26, no. 33, pp. 7451-7457 . https://doi.org/10.1002/chem.202000132
Chemistry (Weinheim an Der Bergstrasse, Germany)
'Chemistry-A European Journal ', vol: 26, pages: 7451-7457 (2020)
Selectivity for monovalent metal ions is an important facet of the function of the metalloregulatory protein CueR. 111Ag perturbed angular correlation of γ‐rays (PAC) spectroscopy probes the metal site structure and the relaxation accompanying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2e8885dded3f35982e72607b8ebba6
https://curis.ku.dk/ws/files/242842319/chem.202000132.pdf
https://curis.ku.dk/ws/files/242842319/chem.202000132.pdf