Intestinal inflammation and increased intestinal permeability in Plasmodium chabaudi AS infected mice [version 2; peer review: 2 approved]

Autor: Jason P Mooney, Christian Bottomley, Rivka Lim, Sophia M DonVito, Lia Pickles, Marianne Keith, Tara Wagner-Gamble, Eleanor A Maguire, Ana Bermejo Pariente, Thomas Oldfield, Adrian A Philbey, Ajoke M Ehimiyien, Eleanor M Riley, Joanne Thompson

Publikováno v: Wellcome Open Research, Vol 7 (2022)

Background: Gastrointestinal symptoms are commonly associated with acute Plasmodium spp infection. Malaria-associated enteritis may provide an opportunity for enteric pathogens to breach the intestinal mucosa, resulting in life-threatening systemic i

Externí odkaz: https://doaj.org/article/fc2331797d1640d395fdfd850c6a3a8d

Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection

Autor: Jason P. Mooney, Tedi Qendro, Marianne Keith, Adrian W. Philbey, Helen T. Groves, John S. Tregoning, Martin R. Goodier, Eleanor M. Riley

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Despite evidence of augmented Natural Killer (NK) cell responses after influenza vaccination, the role of these cells in vaccine-induced immunity remains unclear. Here, we hypothesized that NK cells might increase viral clearance but possibly at the

Externí odkaz: https://doaj.org/article/636a8e32c6524a9cbc524eac8674a57e

Prevalence and Epidemiology of Non-O157 Escherichia coli Serogroups O26, O103, O111, and O145 and Shiga Toxin Gene Carriage in Scottish Cattle, 2014–2015

Autor: David L. Gally, Rebecca K McLean, Margo Chase-Topping, George J. Gunn, Helen Williamson, Marianne Keith, Carol G. Currie, Ian Handel, Nuno Silva, Lesley Allison, Heather A. Mathie, Thibaud Porphyre, MK Henry, Anne Holmes, J Evans, Sue C. Tongue, Rebecca Callaby, Deborah V. Hoyle, Kareen Macleod

Publikováno v: Hoyle, D, Keith, M, Williamson, H, Macleod, K, Mathie, H, Handel, I, Currie, C, Holmes, A, Allison, L, McLean, B, Callaby, R, Porphyre, T, Tongue, S C, Henry, M K, Evans, J, Gunn, G J, Gally, D, Silva, N A & Chase-Topping, M 2021, ' Prevalence and epidemiology of non-O157 Escherichia coli serogroups O26, O103, O111, O145 and Shiga toxin gene carriage in Scottish cattle, 2014-2015. ', Applied and Environmental Microbiology . https://doi.org/10.1128/AEM.03142-20
Applied and Environmental Microbiology
Applied and Environmental Microbiology, 2021, 87 (10), ⟨10.1128/AEM.03142-20⟩

Cattle are reservoirs for Shiga toxin Escherichia coli (STEC), bacteria shed in animal feces. Humans are infected through consumption of contaminated food or water and by direct contact, causing serious disease and kidney failure in the most vulnerab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06c0979b0c0687a8fb65e1901ef49e1
https://doi.org/10.1128/aem.03142-20

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

Autor: Corina Anastasaki, Dasa Longman, Javier F. Cáceres, Graeme R. Grimes, E. Elizabeth Patton, Marianne Keith, Nele Hug

Publikováno v: Nucleic Acids Research
Longman, D, Hug, N, Keith, M, Anastasaki, C, Patton, E E, Grimes, G & Cáceres, J F 2013, ' DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans ', Nucleic Acids Research, vol. 41, no. 17, pp. 8319-31 . https://doi.org/10.1093/nar/gkt585

The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons but also regulates the abundance of cellular RNAs. We sought to identify transcripts that are regulated by two novel NMD factors, DHX34 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13067adcba2c564a7ba7fcb491e15f91
https://doi.org/10.1093/nar/gkt585