Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marianne K.H. Kim"'
Autor:
Charuta Ambardekar, Simge Akbulut, Barbara Canciani, Steven E. Quatela, Priya Aggarwal, Mark Phillips, Alagarsamy Lakku Reddi, Tomas Vilimas, Jacqueline M. Mason, M. Albert Basson, Samuel L. Collins, Jonathan D. Licht, Jonathan D. Powell, Matthew Lovatt, Laura M. Hix, Marianne K.H. Kim
Publikováno v:
Molecular Biology of the Cell
PLCγ03B3 binds Spry1 and Spry2. Overexpression of Spry decreased PLCγ03B3 activity and IP3 and DAG production, whereas Spry-deficient cells yielded more IP3. Spry overexpression inhibited T-cell receptor signaling and Spry1 null T-cells hyperprolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdaeac129bf8099dce9425f92ace9be6
https://doi.org/10.1091/mbc.e10-02-0123
https://doi.org/10.1091/mbc.e10-02-0123
Autor:
Melanie J. McConnell, Tamer E. Fandy, Steven D. Gore, James G. Herman, Yezou Sun, Patrick Kerns, Hetty E. Carraway, Elizabeth A. Sugar, Allen S. Yang, Ibitayo Owoeye, Si Ho Choi, Katharine Oteiza, Lewis R. Silverman, Timothy Aucott, Jonathan D. Licht, Marianne K.H. Kim, Chris A. Nasrallah, Anchalee Jiemjit, Weijia Zhang, Igor Espinoza-Delgado, Tianna Dauses, Anthony J. Murgo, Rosalie Odchimar-Reissig
Publikováno v:
Blood. 114:2764-2773
Sequential administration of DNA methyltransferase (DNMT) inhibitors and histone deacetylase (HDAC) inhibitors has demonstrated clinical efficacy in patients with hematologic malignancies. However, the mechanism behind their clinical efficacy remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8101afc68b5d10749cdfbe79040f91
https://doi.org/10.1182/blood-2009-02-203547
https://doi.org/10.1182/blood-2009-02-203547
Autor:
Aaron Golden, Thomas J. McGarry, Jonathan D. Licht, Pilib Ó Broin, Jared M. Flatow, Marianne K.H. Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(27)
WT1, a critical regulator of kidney development, is a tumor suppressor for nephroblastoma but in some contexts functions as an oncogene. A limited number of direct transcriptional targets of WT1 have been identified to explain its complex roles in tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2ccb71e986590f715365b064b007b1
https://pubmed.ncbi.nlm.nih.gov/19549856
https://pubmed.ncbi.nlm.nih.gov/19549856
Publikováno v:
Molecular cancer research : MCR. 6(7)
In its role as a tumor suppressor, WT1 transactivates several genes that are regulators of cell growth and differentiation pathways. For instance, WT1 induces the expression of the cell cycle regulator p21, the growth-regulating glycoprotein amphireg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e4a25a783488aacb161262b969240e
https://pubmed.ncbi.nlm.nih.gov/18644985
https://pubmed.ncbi.nlm.nih.gov/18644985