Výsledky vyhledávání - "Marianne K. H. Kim"

Akademický článek

A Pathologic Link between Wilms Tumor Suppressor Gene, WT1, and IFI16

Autor: Marianne K-H. Kim, Jacqueline M. Mason, Chi-Ming Li, Windy Berkofsky-Fessler, Le Jiang, Divaker Choubey, Paul E. Grundy, Benjamin Tycko, Jonathan D. Licht

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 1, Pp 69-78 (2008)

The Wilms tumor gene (WT1) is mutated or deleted in patients with heredofamilial syndromes associated with the development of Wilms tumors, but is infrequently mutated in sporadic Wilms tumors. By comparing the microarray profiles of syndromic versus

Externí odkaz: https://doaj.org/article/f7497fb99bff42bd8af8a975efc1d754

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Transcriptional Profiling of Polycythemia Vera Identifies Gene Expression Patterns Both Dependent and Independent from the Action of JAK2V617F

Autor: Raffaele A. Calogero, Ross L. Levine, Melanie J. McConnell, Jonathan D. Licht, Marianne K-H. Kim, Jared M. Bischof, Windy Berkofsky-Fessler, Monica Buzzai, Steven M. Fruchtman, D. Gary Gilliland, Weijia Zhang, Fabricio F. Costa, Dong-Joon Min, Marcelo B. Soares, Vesna Najfeld

Publikováno v: Clinical Cancer Research. 16:4339-4352

Purpose: To understand the changes in gene expression in polycythemia vera (PV) progenitor cells and their relationship to JAK2V617F. Experimental Design: Messenger RNA isolated from CD34+ cells from nine PV patients and normal controls was profiled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c44e8f105e534b3fe7aa072d8711c8f
https://doi.org/10.1158/1078-0432.ccr-10-1092

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Identification of genes that are regulated transcriptionally by Myc in childhood tumors

Autor: Tong Liu, Philip J. Moos, David K. Hooper, Elizabeth A. Raetz, Marianne K. H. Kim, B S Marlee Carlson, Robert Seeger, William L. Carroll, Carol Bruggers, Laura Foot

Publikováno v: Cancer. 98:841-853

BACKGROUND Amplification of the N-myc oncogene is associated with adverse outcomes in the common childhood tumor, neuroblastoma. Because the transforming properties of Myc are related to its ability to modulate gene expression, the authors used cDNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a072684e49cf246f6cb4e5919b4e05f9
https://doi.org/10.1002/cncr.11584

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Exogenous Peptide and Protein Expression Levels Using Retroviral Vectors in Human Cells

Autor: Burt Richards, Mark A. Poritz, Bruce D. Roth, Bob Risley, David H.-F. Teng, Tanya Sandrock, Harry A. Austin, Mark Stump, Karen Repetny, Forrest Hsu, Alexander Kamb, Sanghee Yoo, Marianne K.-H. Kim

Publikováno v: Molecular Therapy. 4(5):398-406

Pseudotyped retroviral vectors combine the advantages of broad host range, high expression, stable chromosomal integration, and ease of preparation. These vectors greatly facilitate delivery into mammalian cells of sequences encoding individual pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9760df3e9d1ebfec337fe543371bde43

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Graded mode of transcriptional induction in yeast pheromone signalling revealed by single-cell analysis

Autor: Marianne K.-H. Kim, Alexander Kamb, Peter J. Rossmeissl, Mark A. Poritz, Sharon Malmstrom

Publikováno v: Yeast. 18:1331-1338

Signalling pathways typically convert a graded, analogue signal into a binary cellular output. In the several eukaryotic systems that have been investigated to date, including MAP kinase cascade activation in Xenopus oocytes, analogue-to-digital conv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d01f8264d67aa4cd66dd80a7f0c20e
https://doi.org/10.1002/yea.777

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Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells

Autor: Stephen Swatkoski, Ji Luo, Poonam Mannan, Jin-Chuan Sheu, Marjan Gucek, Dennis Hsu, Jih-Hsiang Lee, Susan H. Garfield, Curtis C. Harris, Qiuning Li, Shu-Chen Wei, Meng Tzu Weng, Giuseppe Giaccone, Aaron J. Schetter, Michael J. Emanuele, Sina Shahamatdar, Chad J. Creighton, Marianne K. H. Kim, Christina M. Annunziata

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 109(52)

Cancers with Ras mutations represent a major therapeutic problem. Recent RNAi screens have uncovered multiple nononcogene addiction pathways that are necessary for the survival of Ras mutant cells. Here, we identify the evolutionarily conserved gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40483a06cef5b53901454fa6e138fbce
https://pubmed.ncbi.nlm.nih.gov/23236152

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Abstract 3490: Topotecan synergizes with CHEK1 inhibitor to induce apoptosis in ovarian cancer cells

Autor: Marianne K. H. Kim, Jana James, Christina M. Annunziata

Publikováno v: Cancer Research. 75:3490-3490

Background Topotecan is a therapeutic option for women with platinum-resistant or -refractory ovarian cancer. However, the dose-limiting toxicity of topotecan is myelosuppression. This led us to seek a combination treatment to augment topotecan anti-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa3d34a6c1934a3acf206a259ea03ca8
https://doi.org/10.1158/1538-7445.am2015-3490

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