Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Marianne Jochum"'
Autor:
Luiz F Poli-de-Figueiredo, Peter Biberthaler, Charles Simao Filho, Christopher Hauser, Wolf Mutschler, Marianne Jochum
Publikováno v:
Clinics, Vol 61, Iss 1, Pp 41-46 (2006)
BACKGROUND: Release of the neuronal protein S-100B into the circulation has been suggested as a specific indication of neuronal damage. The hypothesis that S-100B is a useful and cost-effective screening tool for the management of minor head injuries
Externí odkaz:
https://doaj.org/article/32a5cba1547b465b884029b2a3909155
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:1970-1982
Human mesenchymal stem cells (hMSC) are subjected to the control of several signal transduction pathways during regeneration processes, whereby Wnt/β-catenin signaling is of pivotal importance. Since there exists only fragmentary knowledge concernin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799f241ddc6375bd342998863c0a207c
https://doi.org/10.1016/j.biocel.2012.07.025
https://doi.org/10.1016/j.biocel.2012.07.025
Autor:
Thomas Tradler, Gerhard Wolber, Jens Feierler, Marianne Jochum, Jochen Pfeifer, Alexander Faussner, Christoph Gibson, Karsten Schnatbaum, Steffen Schüssler, Marcel Bermudez
Publikováno v:
British Journal of Pharmacology. 167:839-853
BACKGROUND AND PURPOSE A 3H-labelled derivative of the novel small-molecule bradykinin (BK) B2 receptor antagonist JSM10292 was used to directly study its binding properties to human and animal B2 receptors in intact cells and to closely define its b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b31f394480b092934b02e4712045540b
https://doi.org/10.1111/j.1476-5381.2012.02054.x
https://doi.org/10.1111/j.1476-5381.2012.02054.x
Autor:
Klaus Dinkel, Jens Feierler, Larisa Ring, Jasmin Leschner, Marianne Jochum, Alexander Faussner
Publikováno v:
bchm. 392:1021-1029
The bradykinin (BK) B2 and B1 receptors (B2R, B1R) belong to the rhodopsin-like G protein-coupled receptors (GPCRs) and are involved in (patho)physiological processes such as blood pressure regulation or inflammation. They mediate the effects of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2864a19c789494109773133b0923e89e
https://doi.org/10.1515/bc.2011.095
https://doi.org/10.1515/bc.2011.095
Publikováno v:
bchm. 392:1011-1020
WNT/Frizzled receptor (FZD) signaling pathways are pivotal for physiological and pathophysiological processes. In humans, the complexity of WNT/FZD signaling is based on 19 WNTs, 10 FZDs and at least two (co)receptors (LRP5/6) mediating supposably fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a7d6dc74e6e1f5d89cce37676b000c
https://doi.org/10.1515/bc.2011.164
https://doi.org/10.1515/bc.2011.164
Autor:
Marlene Tacke, Thomas Reinheckel, Christian P. Sommerhoff, Marianne Jochum, Simon F. Schuster, Steffen Kraus, Dorit K. Nägler, Thea Bunsen, Monika A. Cichoń
Publikováno v:
European Journal of Cell Biology. 90:678-686
Cellular senescence represents a powerful tumor suppressor mechanism to prevent proliferation and invasion of malignant cells. Since tumor cells as well as primary fibroblasts lacking the lysosomal cysteine-type carboxypeptidase cathepsin X exhibit a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f7e37803a4aa4291111f64ae058b71
https://doi.org/10.1016/j.ejcb.2011.03.008
https://doi.org/10.1016/j.ejcb.2011.03.008
Autor:
Yvonne Kienast, Virginia Egea, Christian Ries, Marianne Jochum, Roland Goldbrunner, Peter Neth, Benedikt Berninger, Christian Schichor, L. von Baumgarten, Tanja Popp, Frank Winkler
Publikováno v:
Cell Death & Differentiation. 18:853-863
Bone marrow-derived human mesenchymal stem cells (hMSCs) have become valuable candidates for cell-based therapeutical applications including neuroregenerative and anti-tumor strategies. Yet, the molecular mechanisms that control hMSC trans-differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ef6656affe56e8a12a867a81b3afc9
https://doi.org/10.1038/cdd.2010.154
https://doi.org/10.1038/cdd.2010.154
Autor:
Dorit K. Nägler, Jens Feierler, Alexander Faussner, Friedrich Lottspeich, Steffen Kraus, Marianne Jochum, Reinhard Mentele
Publikováno v:
International Immunopharmacology. 10:134-139
The kallikrein-kinin system and the renin-angiotensin system interact at different levels and are linked by various molecules such as angiotensin-converting enzyme which degrades bradykinin into inactive peptides. Here we report that a cysteine-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f987cc542a3637fddb08db69189b2d0
https://doi.org/10.1016/j.intimp.2009.09.018
https://doi.org/10.1016/j.intimp.2009.09.018
Publikováno v:
Tissue Engineering Part A. 15:2397-2409
The capacity of human mesenchymal stem cells (hMSC) for self-renewal and differentiation is a tightly regulated process within their microenvironment--the stem cell niche. For future therapeutic applications of hMSC within the frame of tissue enginee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea3bd79014087f94799f0fe9fc3b187
https://doi.org/10.1089/ten.tea.2008.0427
https://doi.org/10.1089/ten.tea.2008.0427
Publikováno v:
Toxicology. 263:26-31
Matrix metalloproteinases (MMPs), especially MMP-9 and MMP-2, degrade various proteins of the extracellular matrix, including collagen type IV the major component of basement membranes which also separate the epidermis from the dermis. Although previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4759e5825b611d56c4ce092cd10a795
https://doi.org/10.1016/j.tox.2008.08.011
https://doi.org/10.1016/j.tox.2008.08.011