Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marianne J. Ratcliffe"'
Autor:
Paul Scorer, Marietta Scott, Nicola Lawson, Marianne J. Ratcliffe, Craig Barker, Marlon C. Rebelatto, Jill Walker
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract Background Several anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) therapies have shown encouraging safety and clinical activity in a variety of tumor types. A potential role for PD-L1 testing in identifyi
Externí odkaz:
https://doaj.org/article/43ffde86cf27475dba967a42ba02277c
Autor:
Jill Walker, Marlon C. Rebelatto, Hytham Al-Masri, Paul Scorer, Marietta Scott, Craig Barker, Anita Midha, Alan Sharpe, Marianne J. Ratcliffe
Supplementary Table S1. Comparison of PD-L1 diagnostic assays for patients with NSCLC Supplementary Table S2. Detailed scoring criteria for each assay in the study Supplementary Table S3. Demographics of patients who provided study samples Supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aacfa0b54063413c092e13aaeca054
https://doi.org/10.1158/1078-0432.22466039
https://doi.org/10.1158/1078-0432.22466039
Autor:
Jill Walker, Marlon C. Rebelatto, Hytham Al-Masri, Paul Scorer, Marietta Scott, Craig Barker, Anita Midha, Alan Sharpe, Marianne J. Ratcliffe
Purpose: Immunotherapies targeting programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) demonstrate encouraging antitumor activity and manageable tolerability in non–small cell lung cancer (NSCLC), especially in patients with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6ca4005b4ba30e410ab5f659432998
https://doi.org/10.1158/1078-0432.c.6526226
https://doi.org/10.1158/1078-0432.c.6526226
Autor:
Nicola L. Lawson, Paul W. Scorer, Gareth H. Williams, Michel E. Vandenberghe, Marianne J. Ratcliffe, Craig Barker
Publikováno v:
Modern Pathology. :100220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c727a4903d2ba63553c14f2ecdfd50
https://doi.org/10.1016/j.modpat.2023.100220
https://doi.org/10.1016/j.modpat.2023.100220
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100566 (2014)
Analysis of tumour samples for mutations is becoming increasingly important in driving personalised therapy in cancer. As more targeted therapies are developed, options to survey mutations in multiple genes in a single tumour sample will become ever
Externí odkaz:
https://doaj.org/article/a90f18485989464fbca9253d1d42217f
Autor:
Marietta L. Scott, Marianne J Ratcliffe, Alan Sharpe, Craig Barker, Paul Scorer, Marlon Rebelatto, Hytham Al-Masri, Jill Walker
Publikováno v:
Journal of Clinical Oncology. 35:e14503-e14503
e14503 Background: PD-1/PD-L1 directed antibodies are emerging as effective oncology therapeutics with multiple diagnostic PD-L1 tests available for patient segmentation. It is essential to compare these assays to understand the risk if assays are us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eda80ac54fd6738dd22b2073eaf02d6
https://doi.org/10.1200/jco.2017.35.15_suppl.e14503
https://doi.org/10.1200/jco.2017.35.15_suppl.e14503
Autor:
Eric Frank, Ken Rhodes, Richard C. Krolewski, David L. Kaplan, Karen L. Philpott, Marcie A. Glicksman, Cesare Spadoni, Marianne J. Ratcliffe, Karen Kotkow, Silvia Piccinotti, Piotr Graczyk, Andreas Eilers, Caroline Smales, Martin Raff, Howard Desmond, Alison Linsley O'Neil, Kostas Vekrellis, Freda D. Miller, Jonny Whitfield, Terrence Smith, Mary Jane McCarthy, Patrick Doherty, James E. Schwob, Ceren Ozek, Michael Klymkoswsky, Monica Mota Neumage, Joanne Taylor, Chantal E. Bazenet, Paul Lang, Karina F. Meiri, Feodor Price, Jonathan Ham, Fabian Gusovsky, Christine Gatchalian, Jane Relton
Publikováno v:
Science. 355:806-806
In her News Feature “Out of bounds” (27 January p. [339][1]), A. McCook strove to present an objective narrative of the situation in which a student at Harvard University was forced to undergo a psychiatric evaluation and then filed a court order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d651e74a902a0a272b34c07b7b2820f
https://doi.org/10.1126/science.aam8703
https://doi.org/10.1126/science.aam8703
Publikováno v:
Journal of Biological Chemistry. 275:35680-35683
Protein phosphatase-2A (PP2A) is a multisubunit serine/threonine phosphatase involved in intracellular signaling, gene regulation, and cell cycle progression. Different subunits of PP2A bind to Axin and Adenomatous Polyposis Coli, components of the W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a11f4e85a0e368a92e94c90cec9ddf
https://doi.org/10.1074/jbc.c000639200
https://doi.org/10.1074/jbc.c000639200
Publikováno v:
Molecular and Cellular Biology. 20:2228-2238
Signaling by the Wnt family of secreted proteins plays an important role in animal development and is often misregulated in carcinogenesis. Wnt signal transduction is controlled by the rate of degradation of beta-catenin by a complex of proteins incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c633bf4040403dbab04aa3fbe367ca4
https://doi.org/10.1128/mcb.20.6.2228-2238.2000
https://doi.org/10.1128/mcb.20.6.2228-2238.2000
Publikováno v:
Biochemical Journal. 338:471-478
Inflammatory mediators such as histamine and thrombin increase the tight-junction permeability of endothelial cells. Tight-junction permeability may be independently controlled, but is dependent on the adherens junction, where adhesion is achieved th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26fc1bcbd4e6b7559aad117b37ae8bb
https://doi.org/10.1042/bj3380471
https://doi.org/10.1042/bj3380471