Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marianne J. B. van Stipdonk"'
Autor:
Frits Koning, Marianne J. B. van Stipdonk, Junda M. Kel, Jan W. Drijfhout, Eveline D. de Geus, Lex Nagelkerken
Publikováno v:
International Immunology. 20:117-127
In this study, we investigated the development of T cell responses in mice after administration of a mannosylated ovalbumin peptide (M-OVA(323-339)). Immunization with M-OVA(323-339) in complete adjuvant resulted in enhanced antigen presentation in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1bca698e674dbe2a168a9dca276461
https://doi.org/10.1093/intimm/dxm123
https://doi.org/10.1093/intimm/dxm123
Autor:
Andres Alonso, Tomas Mustelin, Souad Rahmouni, Marianne J. B. van Stipdonk, Chiara Soncini, Torkel Vang, Michel Moutschen, Stephen P. Schoenberger, Scott Williams
Publikováno v:
Molecular and Cellular Biology. 25:2227-2241
The molecular mechanisms of T-cell-antigen receptor (TCR) signal transduction and T-cell activation have been intensely studied during the past decade. It has become evident that several protein tyrosine kinases (PTKs) and protein tyrosine phosphatas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1804060f552115257c1182fd480da0c4
https://doi.org/10.1128/mcb.25.6.2227-2241.2005
https://doi.org/10.1128/mcb.25.6.2227-2241.2005
Autor:
Andres Alonso, Tomas Mustelin, Lukasz Jaroszewski, Robert T. Abraham, Souad Rahmouni, Marianne J. B. van Stipdonk, Adam Godzik, Stephen P. Schoenberger, Scott Williams
Publikováno v:
Nature Immunology. 4:44-48
The ZAP-70 tyrosine kinase is a key component of the signaling machinery for the T cell antigen receptor (TCR). Whereas recruitment and activation of ZAP-70 are relatively well understood, the proteins phosphorylated by ZAP-70 are incompletely known.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e62859d906a0a581d5b0ec2241ec3c8
https://doi.org/10.1038/ni856
https://doi.org/10.1038/ni856
Autor:
Tom Wolfe, Kiley R. Prilliman, Angelika Jahreis, Matthias von Herrath, Marianne J. B. van Stipdonk, Bryan Coon, Anna Hughes, Stephen P. Schoenberger, Dirk Homann
Publikováno v:
Immunity. 16(3):403-415
Systemic treatment with antibody to CD40 ligand (aCD40L) can prevent autoimmunity and transplant rejection in several animal models and is currently under evaluation in clinical trials. While it is known that aCD40L administration inhibits expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16822eaaec67c28ea2eb5ebb5b91fb31
Publikováno v:
Nature Immunology. 2:423-429
In defense of the host, the immune system must often raise an effective cytotoxic T lymphocyte (CTL) response from a small number of clonal precursors. The degree to which activation stimuli regulate the expansion and differentiation of naive CTLs, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd1722935214d494f82172141010bf1
https://doi.org/10.1038/87730
https://doi.org/10.1038/87730
Autor:
Arianne C. van Sechel, Jeffrey J. Bajramovic̀, Marianne J. B. van Stipdonk, Carla Persoon-Deen, Sacha B. Geutskens, Johannes M. van Noort
Publikováno v:
The Journal of Immunology. 162:129-135
The development of multiple sclerosis is most likely influenced by autoimmune responses to central nervous system myelin proteins as well as by infections with common viruses such as EBV and human herpesvirus-6. However, much remains to be establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::059c98d9844646b071fe40a101bd5a9f
https://doi.org/10.4049/jimmunol.162.1.129
https://doi.org/10.4049/jimmunol.162.1.129
Separate Roles for Antigen Recognition and Lymph Node Inflammation in CD8(+) Memory T Cell Formation
Autor:
Marieke F. Fransen, Cornelis J. M. Melief, Stephen P. Schoenberger, Marjolein Sluijter, Rienk Offringa, Marianne J. B. van Stipdonk
Publikováno v:
Journal of Immunology, 185(6), 3167-3173
Priming of naive CD8+ T cells by pathogens or vaccines generally involves their interaction with Ag-loaded dendritic cells (DCs) in the context of an inflamed lymph node. Lymph node activation fosters DC and T cell encounters and subsequently provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39e259d7ddff741381ab72544a22d15
https://doi.org/10.4049/jimmunol.0904046
https://doi.org/10.4049/jimmunol.0904046
Autor:
Thorbald van Hall, Marjolein Sluijter, Daniel Badia-Martinez, Marianne J. B. van Stipdonk, Adnane Achour, Rienk Offringa
Publikováno v:
Cancer research. 69(19)
Immunogenicity of tumor-associated antigens (TAA) is often weak because many TAA are autoantigens for which the T-cell repertoire is sculpted by tolerance mechanisms. Substitutions at main anchor positions to increase the complementarity between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40858ae1990ff6a5e9d0a6133fc886e8
https://pubmed.ncbi.nlm.nih.gov/19789338
https://pubmed.ncbi.nlm.nih.gov/19789338