Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Marianne G, Rots"'
Autor:
Marloes M. Oosterhof, Louis Coussement, Alienke van Pijkeren, Marcel Kwiatkowski, Martijn R. H. Zwinderman, Frank J. Dekker, Tim de Meyer, Vera A. Reitsema, Rainer Bischoff, Victor Guryev, Hjalmar R. Bouma, Rob H. Henning, Marianne G. Rots
Publikováno v:
Epigenetics Communications, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background Hibernation (torpor) is a strategy to survive extreme environmental conditions, associated with a significant decrease in metabolism and body temperature. The inducibility by the environment of torpor for facultative hibernators d
Externí odkaz:
https://doaj.org/article/69c8df83b754412d957260d7a49f95cc
Autor:
Dan-Dan Wu, Andy T. Y. Lau, Yan-Ming Xu, Marjan Reinders-Luinge, Mihaly Koncz, Antal Kiss, Wim Timens, Marianne G. Rots, Machteld N. Hylkema
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is highly expressed in smokers, but little is known about the molecular mechanism of UCHL1 in airway epithelium and its possible role in affecting extracellular matrix (ECM) remodelling in the underlyi
Externí odkaz:
https://doaj.org/article/2a12fdb3945348458e0b03b9495d19c6
Autor:
Archibold Mposhi, Fabian Cortés-Mancera, Janette Heegsma, Vincent E. de Meijer, Bart van de Sluis, Svenja Sydor, Lars P. Bechmann, Claudia Theys, Peter de Rijk, Tim De Pooter, Wim Vanden Berghe, İkbal Agah İnce, Klaas Nico Faber, Marianne G. Rots
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionHepatic lipid accumulation and mitochondrial dysfunction are hallmarks of metabolic associated fatty liver disease (MAFLD), yet molecular parameters underlying MAFLD progression are not well understood. Differential methylation within the
Externí odkaz:
https://doaj.org/article/1824ad711d384cc69785ea814dba5292
Autor:
Federica Sarno, Désirée Goubert, Emilie Logie, Martijn G. S. Rutten, Mihaly Koncz, Christophe Deben, Anita E. Niemarkt, Lucia Altucci, Pernette J. Verschure, Antal Kiss, Wim Vanden Berghe, Marianne G. Rots
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 102 (2022)
Plasminogen activator, urokinase (PLAU) is involved in cell migration, proliferation and tissue remodeling. PLAU upregulation is associated with an increase in aggressiveness, metastasis, and invasion of several cancer types, including breast cancer.
Externí odkaz:
https://doaj.org/article/96a430b70388450ba692e106845876d2
Autor:
Dieuwertje M. Mossel, Kondaiah Moganti, Vladimir Riabov, Christel Weiss, Stefan Kopf, Julio Cordero, Gergana Dobreva, Marianne G. Rots, Harald Klüter, Martin C. Harmsen, Julia Kzhyshkowska
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The number of diabetic patients in Europe and world-wide is growing. Diabetes confers a 2-fold higher risk for vascular disease. Lack of insulin production (Type 1 diabetes, T1D) or lack of insulin responsiveness (Type 2 diabetes, T2D) causes systemi
Externí odkaz:
https://doaj.org/article/95aaa7a981b744909b62d99ebf7485a3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Like the nucleus, mitochondria contain their own DNA and recent reports provide accumulating evidence that also the mitochondrial DNA (mtDNA) is subjective to DNA methylation. This evidence includes the demonstration of mitochondria-localise
Externí odkaz:
https://doaj.org/article/25dc5d0acc3d498d832bc3739fe8b849
Autor:
Hui Chen, Qing‐Lin Yang, Jia‐Xi Xu, Xuan Deng, Yun‐Jie Zhang, Ting Liu, Marianne G. Rots, Guo‐Liang Xu, Kai‐Yao Huang
Publikováno v:
The Plant Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8237b92fa8fa7faa44340c2926537d
https://doi.org/10.1111/tpj.16265
https://doi.org/10.1111/tpj.16265
Autor:
Louis Coussement, Marloes M. Oosterhof, Victor Guryev, Vera A. Reitsema, Jojanneke J. Bruintjes, Maaike Goris, Hjalmar R. Bouma, Tim de Meyer, Marianne G. Rots, Robert H. Henning
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 290
Hibernation consists of alternating torpor–arousal phases, during which animals cope with repetitive hypothermia and ischaemia-reperfusion. Due to limited transcriptomic and methylomic information for facultative hibernators, we here conducted RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c388665aff2307a2f777f2267b867170
https://doi.org/10.1098/rspb.2023.0368
https://doi.org/10.1098/rspb.2023.0368
Autor:
Marianne G. Rots, Geke A.P. Hospers, Klaas Kok, Pieter van der Vlies, Hinke G. Kazemier, Christian Huisman, Fahimeh Falahi
The human epidermal growth factor receptor-2 (HER2/neu/ERBB2) is overexpressed in several cancer types. Although therapies targeting the HER2/neu protein result in inhibition of cell proliferation, the anticancer effect might be further optimized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1013f2d8057392765c2f39d648f4eb4f
https://doi.org/10.1158/1541-7786.c.6539662
https://doi.org/10.1158/1541-7786.c.6539662
Autor:
Marianne G. Rots, Geke A.P. Hospers, Klaas Kok, Pieter van der Vlies, Hinke G. Kazemier, Christian Huisman, Fahimeh Falahi
PDF file - 72K, Sorted cells maintain their profile of Her2/neu and GFP expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b8e936cc60433048697f48d1eed87
https://doi.org/10.1158/1541-7786.22510588.v1
https://doi.org/10.1158/1541-7786.22510588.v1