Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marianne Ellman"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 28:361-364
The tissue distribution of estramustine and estromustine, two cytotoxic lipophilic metabolites of estramustine phosphate (Estracyt, EMP) was studied in rats and humans. A single dose of [3H]-estramustine was given i.v. to groups of rats. At 24 h afte
Autor:
Gary Hudes, Naomi Haas, Gwen Yeslow, Thomas Gillon, Per Olov Gunnarsson, Marianne Ellman, Orjan Nordle, Brigitta Eriksson, Langdon Miller, Laura Cisar, Michael Kopreski, Donatella Viaro, Beryl Hartley-Asp
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(4)
PURPOSE: To determine the dose-limiting toxicities, maximum-tolerated dose, and pharmacokinetics of intravenous estramustine phosphate (IV EMP). PATIENTS AND METHODS: A total of 31 patients with hormone-refractory prostate cancer received IV EMP as a
Autor:
Marianne Ellman, Per Olov Gunnarsson, J. Polacek, Heine H. Hansen, K. Hansson, J. Vibe-Petersen, Beryl Hartley-Asp
Publikováno v:
Cancer chemotherapy and pharmacology. 38(4)
Tauromustine (TCNU) is an exploratory drug that has demonstrated activity in various solid tumors. We examined chromosome aberrations and plasma levels of the drug in two groups of patients receiving either a single dose of 130 mg/m2 or 40 mg/m2 on 3
Autor:
Per Olov Gunnarsson, Marianne Ellman, Kjell Gunnarsson, Gunborg Jensen, Müntzing J, Eva Fabiansson
Publikováno v:
Acta pharmacologica et toxicologica. 49(4)
LS 1727, a nitroso-chloroethyl carbamate of 19-nortestosterone, given intraperitoneally had a high cytostatic activity against some experimental tumours. In vitro studies showed that the tested tumours differed in their ability to hydrolyze LS 1727.