Zobrazeno 1 - 10
of 417
pro vyhledávání: '"Marianne C. Verhaar"'
Autor:
Robin W. M. Vernooij, Anne‐Mar L. N. vanOmmen, Gideon B. Valstar, Maarten Jan Cramer, Arco J. Teske, Roxana Menken, Leo Hofstra, Frans H. Rutten, Michiel L. Bots, Hester M. denRuijter, Marianne C. Verhaar
Publikováno v:
ESC Heart Failure, Vol 11, Iss 1, Pp 315-326 (2024)
Abstract Aims We aim to investigate the association between kidney dysfunction and left ventricular diastolic dysfunction parameters and heart failure with preserved ejection fraction (HFpEF) and whether this is sex‐specific. Methods and results We
Externí odkaz:
https://doaj.org/article/998951c090c44a769f766a3be0dde6f1
Autor:
Vivian V. T. Nguyen, Joshua A. Welsh, Tobias Tertel, Andre Choo, Simonides I. van deWakker, Kyra A. Y. Defourny, Bernd Giebel, Pieter Vader, Jayanthi Padmanabhan, Sai Kiang Lim, Esther N. M. Nolte‐'t Hoen, Marianne C. Verhaar, R. Beklem Bostancioglu, Antje M. Zickler, Jia Mei Hong, Jennifer C. Jones, Samir EL Andaloussi, Bas W. M. vanBalkom, André Görgens
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily exert their effects through secreted extracellular vesicles (EVs). These EVs – being small and non‐living – are easier to handle and possess advant
Externí odkaz:
https://doaj.org/article/ae35180078c5434b854c0344b3d59bb2
Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease
Autor:
Fjodor A. Yousef Yengej, Carla Pou Casellas, Carola M.E. Ammerlaan, Charlotte J.A. Olde Hanhof, Emre Dilmen, Joep Beumer, Harry Begthel, Elise M.G. Meeder, Joost G. Hoenderop, Maarten B. Rookmaaker, Marianne C. Verhaar, Hans Clevers
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113614- (2024)
Summary: Organoid technology is rapidly gaining ground for studies on organ (patho)physiology. Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The progenitor state of expanding tubuloids comes at the expense of di
Externí odkaz:
https://doaj.org/article/0b0f29d1d0104197b48e1e0d9de49d2d
Autor:
Carla Pou Casellas, Cayetano Pleguezuelos-Manzano, Maarten B. Rookmaaker, Marianne C. Verhaar, Hans Clevers
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Single-cell RNA sequencing has recently led to the identification of a flurry of rare, new cell types, such as the CFTR-high ionocytes in the airway epithelium. Ionocytes appear to be specifically responsible for fluid osmolarity and pH regu
Externí odkaz:
https://doaj.org/article/c87fad1e558047af81e4a39f6de2362b
Autor:
Julia M. T. Colombijn, Demy L. Idema, Kim van der Braak, Rene Spijker, Sabine C. A. Meijvis, Michiel L. Bots, Lotty Hooft, Marianne C. Verhaar, Robin W. M. Vernooij
Publikováno v:
Systematic Reviews, Vol 11, Iss 1, Pp 1-8 (2022)
Abstract Background Patients with chronic kidney disease (CKD) require a personalised strategy for cardiovascular risk management (CVRM) to reduce their high risk of cardiovascular morbidity and mortality. Despite their high risk, patients with CKD a
Externí odkaz:
https://doaj.org/article/d1978a65d44d4b5295ac4751dbc259c2
Autor:
Paul J. Besseling, Merle M. Krebber, Joost O. Fledderus, Martin Teraa, Krista den Ouden, Melanie van de Kaa, Petra M. de Bree, Aurelie Serrero, Carlijn V. C. Bouten, Patricia Y. W. Dankers, Martijn A. J. Cox, Marianne C. Verhaar
Publikováno v:
APL Bioengineering, Vol 7, Iss 2, Pp 026107-026107-12 (2023)
Vascular in situ tissue engineering encompasses a single-step approach with a wide adaptive potential and true off-the-shelf availability for vascular grafts. However, a synchronized balance between breakdown of the scaffold material and neo-tissue f
Externí odkaz:
https://doaj.org/article/576e9e71f08d4945ac29a81368da757c
Autor:
Vivian V. T. Nguyen, Vasiliki Gkouzioti, Christian Maass, Marianne C. Verhaar, Robin W. M. Vernooij, Bas W. M. van Balkom
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/a45d2e85a7cb4764bcfaaefb13da4219
Autor:
Rafael Soares Lindoso, Fjodor A. Yousef Yengej, Franziska Voellmy, Maarten Altelaar, Estela Mancheño Juncosa, Theano Tsikari, Carola M. E. Ammerlaan, Bas W. M. Van Balkom, Maarten B. Rookmaaker, Marianne C. Verhaar, Rosalinde Masereeuw
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract The prevalence of end-stage kidney disease (ESKD) is rapidly increasing with the need for regenerative therapies. Adult stem cell derived kidney tubuloids have the potential to functionally mimic the adult kidney tubule, but still lack the e
Externí odkaz:
https://doaj.org/article/331cae23c0ff4b0498dd6f9d94d91a78
Autor:
João Faria, Sabbir Ahmed, Dimitrios Stamatialis, Marianne C. Verhaar, Rosalinde Masereeuw, Karin G. F. Gerritsen, Silvia M. Mihăilă
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12435 (2023)
Patients with end-stage kidney disease (ESKD) suffer from high levels of protein-bound uremic toxins (PBUTs) that contribute to various comorbidities. Conventional dialysis methods are ineffective in removing these PBUTs. A potential solution could b
Externí odkaz:
https://doaj.org/article/069ce47ad04b47809b09858af751a200
Autor:
Vivian V. T. Nguyen, Shicheng Ye, Vasiliki Gkouzioti, Monique E. vanWolferen, Fjodor Yousef Yengej, Dennis Melkert, Sofia Siti, Bart deJong, Paul J. Besseling, Bart Spee, Luc J. W. van derLaan, Reyk Horland, Marianne C. Verhaar, Bas W. M. vanBalkom
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 11, Pp n/a-n/a (2022)
Abstract Mesenchymal stromal cell (MSC)‐derived small extracellular vesicles (sEVs) show therapeutic potential in multiple disease models, including kidney injury. Clinical translation of sEVs requires further preclinical and regulatory development
Externí odkaz:
https://doaj.org/article/0bfe9b51c350456fa7665cedf2f8b71f