Výsledky vyhledávání - "Marianne A. J. A. van Sterkenburg"

Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins

Autor: Abraham C. van der Linden, Sandra van Wetering, Willem I. de Boer, Pieter S. Hiemstra, Joost Schalkwijk, A.L.A. Kuijpers, Marianne A. J. A. van Sterkenburg

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 278:L51-L58

Secretory leukocyte proteinase inhibitor (SLPI) is a serine proteinase inhibitor that is produced locally in the lung by cells of the submucosal bronchial glands and by nonciliated epithelial cells. Its main function appears to be the inhibition of n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb77cdf3f03ba3d490e6361b042f68a5
https://doi.org/10.1152/ajplung.2000.278.1.l51

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IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides

Autor: Marianne A. J. A. van Sterkenburg, Jasmijn A. Schrumpf, Klaus F. Rabe, Suzanne Zuyderduyn, Pieter S. Hiemstra, Frans A. Prins, Dennis K. Ninaber, Sandra van Wetering, Renate M. Verhoosel

Publikováno v: Respiratory Research, 12
Respiratory Research, Vol 12, Iss 1, p 59 (2011)
Respiratory Research

The airway epithelium forms a barrier against infection but also produces antimicrobial peptides (AMPs) and other inflammatory mediators to activate the immune system. It has been shown that in allergic disorders, Th2 cytokines may hamper the antimic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fbdba6180d38f088192a1a47fb78a1
http://hdl.handle.net/1887/117942

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Cigarette Smoke Extract Affects Release Of IL-8 And SLPI In Differentiated Primary Bronchial Epithelial Cell Cultures (PBEC) From COPD Versus Controls

Autor: Suzanne Zuyderduyn, Pieter S. Hiemstra, Marianne A. J. A. van Sterkenburg, Klaus F. Rabe, Jasmijn A. Schrumpf

Publikováno v: A65. MECHANISMS OF AIRWAY RESPONSE TO INJURY (RESPIRATORY VIRUSES, CIGARETTE SMOKE, AND ASTHMA).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eba07156d4682bfbeb25275a7deeb9dc
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2082

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Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13

Autor: Klaus F. Rabe, Dennis K. Ninaber, Pieter S. Hiemstra, Sandra van Wetering, Marianne A. J. A. van Sterkenburg, Suzanne Zuyderduyn

Publikováno v: Molecular immunology. 44(5)

The composition of the airway epithelium is dynamic and epithelial differentiation is regulated by endogenous mediators as well as inhaled substances. In atopic asthma the differentiation of the epithelium is altered. Various studies have addressed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98aacac3d8d8e93fd7f4d5e94b9ad20
https://pubmed.ncbi.nlm.nih.gov/16740309

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Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense

Autor: Marianne A. J. A. van Sterkenburg, Joost B. Vos, Pieter S. Hiemstra, Joost Schalkwijk, Nicole A. Datson, Klaus F. Rabe

Publikováno v: Physiological Genomics, 21, 3, pp. 324-36
Physiological Genomics, 21, 324-36

Contains fulltext : 47709schalkwijk.pdf (Publisher’s version ) (Closed access) The airway epithelium responds to microbial exposure by altering expression of a variety of genes to increase innate host defense. We aimed to delineate the early transc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bc70ea561ead0972d080f5ced0c110
https://doi.org/10.1152/physiolgenomics.00289.2004

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Rhinovirus increases human beta-defensin-2 and -3 mRNA expression in cultured bronchial epithelial cells

Autor: Elisabeth van Strijen, S. P. G. Mannesse-Lazeroms, Pieter S. Hiemstra, Peter H. Nibbering, Louise A. Duits, Marianne A. J. A. van Sterkenburg, Joost B. Vos

Publikováno v: FEMS immunology and medical microbiology. 38(1)

Human beta-defensins (hBDs) are antimicrobial peptides that play important roles in host defense against infection, inflammation and immunity. Previous studies showed that micro-organisms and proinflammatory mediators regulate the expression of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103e5ad09747b4b69d056cd7ba55e3f0
https://pubmed.ncbi.nlm.nih.gov/12900056

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Inhibition of hBD-3, but not hBD-1 and hBD-2, mRNA expression by corticosteroids

Autor: Bep Ravensbergen, Peter H. Nibbering, Elizabeth van Strijen, Louise A. Duits, Pieter S. Hiemstra, Marianne A. J. A. van Sterkenburg, Mirjam Rademaker

Publikováno v: Biochemical and biophysical research communications. 280(2)

Intensive use of corticosteroids may be accompanied by increased susceptibility to infections; hence, we investigated the effects of dexamethasone on the expression of antimicrobial peptides, termed human β-defensins (hBD), by cultured bronchial epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9413218e6c22567d48b5bcda866aaf4
https://pubmed.ncbi.nlm.nih.gov/11162549

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