Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marianna Romzova"'
Publikováno v:
Practical Laboratory Medicine, Vol 25, Iss , Pp e00210- (2021)
BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital P
Externí odkaz:
https://doaj.org/article/b9147eff25494ab38b272b3f709e80ff
Autor:
Andrea Stofkova, Blanka Zelezna, Marianna Romzova, Olga Ulicna, Alexander Kiss, Martina Skurlova, Jana Jurcovicova
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
We studied the effect of food restriction, overfeeding, and normofeeding on cachexia, inflammatory and metabolic parameters, and insulin sensitivity in chronic adjuvant arthritis (AA) in rats. Food restriction during AA increased circulating ghrelin,
Externí odkaz:
https://doaj.org/article/531b1b9201eb43d48278084491621917
Autor:
Daniela Zackova, Zdenek Racil, Tomáš Jurček, Zdenka Herudkova, Martin Čulen, Jiri Mayer, Tomáš Loja, Lukas Stejskal, Marianna Romzova, Dagmar Smitalová, Jakub Hynšt, Nikola Tom
Publikováno v:
British journal of haematologyReferences. 194(3)
There is an emerging body of evidence that patients with chronic myeloid leukaemia (CML) may carry not only breakpoint cluster region-Abelson murine leukaemia viral oncogene homologue 1 (BCR-ABL1) kinase domain mutations (BCR-ABL1 KD mutations), but
Publikováno v:
Practical Laboratory Medicine, Vol 25, Iss, Pp e00210-(2021)
BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital P
Publikováno v:
Practical Laboratory Medicine
BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital P
Autor:
Marianna Romzova, Daniela Zackova, Tomáš Jurček, Martin Čulen, Jiri Mayer, Nikola Tom, Zdenek Racil, Dagmar Smitalová
Publikováno v:
British journal of haematologyReferences. 189(3)
The occurrence of mutations in the BCR-ABL1 kinase domain (KD) can lead to treatment resistance in chronic myeloid leukaemia patients. Nowadays, next-generation sequencing (NGS) is an alternative method for the detection of kinase domain mutations, c
Publikováno v:
Blood. 134:2920-2920
BACKGROUND: Bcr-abl1 oncogene targeted treatment with tyrosine kinase inhibitors (TKI) showed an impressive efficacy against proliferating chronic myeloid leukemia (CML) cells. However, rapid relapses in more than half of CML patients after discontin
Autor:
Daniela Hohenadel, Sarka Ruzickova, Daniela Pinterova, Marie Cerna, Ivan Rychlik, Vladimir Bosak, Katarina Kolostova, Markéta Fojtíková, Marianna Romzova, Ctibor Dostál
Publikováno v:
Human Immunology. 67:706-713
Nuclear factor kappa B (NFkappaB) is an important transcription factor that together with its inhibitor (IkappaB) participates in the activation of genes involved in immune responses. We examined the CA repeat polymorphism of the NFKB1 gene (encoding
Autor:
Idan Cohen, Yakov Krelin, Shahar Dotan, Marianna Romzova, Peleg Rider, Xiaoping Song, Irena Kaplanov, Moshe Elkabets, Yaron Carmi, Ron N. Apte, Elena Voronov
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology, Vol 4 (2013)
Interleukin-1 (IL-1) is a major “alarm” upstream pro-inflammatory cytokine that also affects immunity and hematopoiesis by inducing cytokine cascades. In the tumor arena, IL-1 is produced by malignant or microenvironmental cells. As a pleiotropic
Autor:
Ron N. Apte, Alex Braiman, Liora Bernardis, Elena Voronov, Marianna Romzova, Peleg Rider, Irena Kaplanov
Publikováno v:
Frontiers in Immunology; Vol 3
Frontiers in Immunology
Frontiers in Immunology, Vol 3 (2012)
Frontiers in Immunology
Frontiers in Immunology, Vol 3 (2012)
During hypoxia, cells undergo transcriptional changes to adjust to metabolic stress, to promote cell survival and to induce pro-angiogenic factors. Hypoxia induced factors (HIFs) regulate these transcriptional alterations. Failure to restore oxygen l