Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marianna Mekhaeil"'
Autor:
Electra Brunialti, Alessandro Villa, Marianna Mekhaeil, Federica Mornata, Elisabetta Vegeto, Adriana Maggi, Donato A. Di Monte, Paolo Ciana
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Homozygotic mutations in the GBA gene cause Gaucher’s disease; moreover, both patients and heterozygotic carriers have been associated with 20- to 30-fold increased risk of developing Parkinson’s disease. In homozygosis, these
Externí odkaz:
https://doaj.org/article/62da70b9331f4c14a2113b7421d32bde
Autor:
Jennifer Moran, Eimear Mylod, Laura E. Kane, Caroline Marion, Emily Keenan, Marianna Mekhaeil, Joanne Lysaght, Kumlesh K. Dev, Jacintha O’Sullivan, Melissa J. Conroy
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 360 (2023)
Glioblastoma multiforme (GBM) is the most common adult primary brain malignancy, with dismal survival rates of ~14.6 months. The current standard-of-care consists of surgical resection and chemoradiotherapy, however the treatment response is limited
Externí odkaz:
https://doaj.org/article/7c0190764d2e4db88ffa5da6ec031cef
Publikováno v:
Cancers, Vol 14, Iss 687, p 687 (2022)
Over the past decade, Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors have arisen as a novel and promising targeted therapy for breast cancer gene (BRCA)-mutated ovarian and breast cancer patients. Therapies targeting the enzyme, PARP-1, have sinc