Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent

Autor: Martin Korte, Eicke Latz, Anita Remus, Michael T. Heneka, Marianna M.S. Beyer, Niklas Lonnemann

Publikováno v: The journal of neuroscience 40(28), 5480-5494 (2020). doi:10.1523/JNEUROSCI.0200-20.2020
The Journal of neuroscience : the official journal of the Society for Neuroscience
United States
J Neurosci

Neuroinflammation can be caused by various insults to the brain and represents an important pathologic hallmark of neurodegenerative diseases including Alzheimer's disease (AD). Infection-triggered acute systemic inflammation is able to induce neuroi

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