Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marianna Holczer"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-11 (2021)
Abstract Although autophagy is a type of programmed cell death, it is also essential for cell survival upon tolerable level of various stress events. For the cell to respond adequately to an external and/or internal stimulus induced by cellular stres
Externí odkaz:
https://doaj.org/article/497b3ae8897f49189f64a29350c27456
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1587 (2022)
Autophagy-dependent cellular survival is tightly regulated by both kinases and phosphatases. While mTORC1 inhibits autophagy by phosphorylating ULK1, PP2A is able to remove this phosphate group from ULK1 and promotes the key inducer of autophagosome
Externí odkaz:
https://doaj.org/article/3b112ba28ed94705bc680f5f653c476d
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168359 (2016)
The balance of protein synthesis and proteolysis (i.e. proteostasis) is maintained by a complex regulatory network in which mTOR (mechanistic target of rapamycin serine/threonine kinase) pathway and unfolded protein response are prominent positive an
Externí odkaz:
https://doaj.org/article/bf1ce07aa1654ed0be37e26f4a3bcf04
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7671
One of the main inducers of autophagy-dependent self-cannibalism, called ULK1, is tightly regulated by the two sensor molecules of nutrient conditions and energy status, known as mTOR and AMPK kinases, respectively. Recently, we developed a freely av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880a9257449f5c74b98382934c9b2300
https://doi.org/10.3390/ijms24087671
https://doi.org/10.3390/ijms24087671
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Although autophagy is a type of programmed cell death, it is also essential for cell survival upon tolerable level of various stress events. For the cell to respond adequately to an external and/or internal stimulus induced by cellular stress, autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a3bba2521f5454c6c728ad7ae76690
https://doaj.org/article/497b3ae8897f49189f64a29350c27456
https://doaj.org/article/497b3ae8897f49189f64a29350c27456
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Autophagy is an intracellular digestive process, which has a crucial role in maintaining cellular homeostasis by self-eating the unnecessary and/or damaged components of the cell at various stress events. ULK1, one of the key elements of autophagy ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f637585200a1ad074bc42b4771c57bdc
http://europepmc.org/articles/PMC7576158
http://europepmc.org/articles/PMC7576158
Publikováno v:
International Journal of Molecular Sciences; Volume 20; Issue 22; Pages: 5543
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5543 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5543 (2019)
International Journal of Molecular Sciences
Cellular homeostasis is controlled by an evolutionary conserved cellular digestive process called autophagy. This mechanism is tightly regulated by the two sensor elements called mTORC1 and AMPK. mTORC1 is one of the master regulators of proteostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e74aa80cbe693ec963bd433d8c9d41c
Publikováno v:
Pathology oncology research : POR. 25(2)
Pharmacologic ascorbate induced cell death and ferroptosis share common features such as iron dependency, production of ROS, lipid peroxidation, caspase independency and the possible involvement of autophagy. These observations lead us to hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e29f45025c10c05148380342e4132d5
https://pubmed.ncbi.nlm.nih.gov/30443843
https://pubmed.ncbi.nlm.nih.gov/30443843
Autor:
Marianna Holczer, Boglárka Besze, Orsolya Kapuy, Veronika Zámbó, Miklós Csala, Gábor Bánhegyi
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
The maintenance of cellular homeostasis is largely dependent on the ability of cells to give an adequate response to various internal and external stimuli. We have recently proposed that the life-and-death decision in endoplasmic reticulum (ER) stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05f804720d25dc64526903e662c744c
https://doaj.org/article/0a35a635945445d79f3c97fe7c6ef882
https://doaj.org/article/0a35a635945445d79f3c97fe7c6ef882
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7a875ddff9eddb26b027f38f4df89a
https://doi.org/10.1155/2015/319589
https://doi.org/10.1155/2015/319589