Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Marianna A Tryfonidou"'
Autor:
Frances C Bach, Lisanne T Laagland, Michael P Grant, Laura B Creemers, Keita Ito, Björn P Meij, Fackson Mwale, Marianna A Tryfonidou
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187831 (2017)
Degeneration of the intervertebral disc (IVD) is a frequent cause for back pain in humans and dogs. Link-N stabilizes proteoglycan aggregates in cartilaginous tissues and exerts growth factor-like effects. The human variant of Link-N facilitates IVD
Externí odkaz:
https://doaj.org/article/09edd18fe1d9499f9a140f5562c07881
Autor:
Silviu Sbiera, Marianna A Tryfonidou, Isabel Weigand, Guy C M Grinwis, Bart Broeckx, Sabine Herterich, Bruno Allolio, Timo Deutschbein, Martin Fassnacht, Björn P Meij
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0169009 (2016)
Cushing's disease (CD), also known as pituitary-dependent hyperadrenocorticism, is caused by adrenocorticotropic hormone (ACTH)-secreting pituitary tumours. Affected humans and dogs have similar clinical manifestations, however, the incidence of the
Externí odkaz:
https://doaj.org/article/68586dba240044599062f2469bddc052
Autor:
Ineke C M Lavrijsen, Peter A J Leegwater, Alan J Martin, Stephen J Harris, Marianna A Tryfonidou, Henri C M Heuven, Herman A W Hazewinkel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87735 (2014)
Hip dysplasia, an abnormal laxity of the hip joint, is seen in humans as well as dogs and is one of the most common skeletal disorders in dogs. Canine hip dysplasia is considered multifactorial and polygenic, and a variety of chromosomal regions have
Externí odkaz:
https://doaj.org/article/ba13d8bad3194b8eb1a42aa622432bc2
Autor:
Frank Niemeyer, Fabio Galbusera, Martijn Beukers, René Jonas, Youping Tao, Marion Fusellier, Marianna A. Tryfonidou, Cornelia Neidlinger‐Wilke, Annette Kienle, Hans‐Joachim Wilke
Publikováno v:
JOR Spine, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background Intervertebral disc degeneration is frequent in dogs and can be associated with symptoms and functional impairments. The degree of disc degeneration can be assessed on T2‐weighted MRI scans using the Pfirrmann classification sch
Externí odkaz:
https://doaj.org/article/c5243798e06b4187acb440048fa9f106
Autor:
Irin Kwananocha, Joëll Magré, Amir Kamali, Femke Verseijden, Koen Willemsen, Yuntao Ji, Bart C. H. van der Wal, Ralph J. B. Sakkers, Marianna A. Tryfonidou, Björn P. Meij
Publikováno v:
Animals, Vol 14, Iss 16, p 2385 (2024)
The acetabular rim extension (ACE-X) implant is a custom-made three-dimensionally printed titanium device designed for the treatment of canine hip dysplasia. In this study, 34 dogs (61 hips) underwent ACE-X implantation, and assessments were conducte
Externí odkaz:
https://doaj.org/article/39c2311138974261998a9330c812f5c0
Autor:
Thomas Bitterli, David Schmid, Ladina Ettinger, Olga Krupkova, Frances C. Bach, Marianna A. Tryfonidou, Björn P. Meij, Antonio Pozzi, Frank Steffen, Karin Wuertz‐Kozak, Lucas A. Smolders
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background The regulation of inflammatory mediators in the degenerating intervertebral disc (IVD) and corresponding ligamentum flavum (LF) is a topic of emerging interest. The study aimed to investigate the expression of a broad array of inf
Externí odkaz:
https://doaj.org/article/a0130bc574964e6baf2eee7b83f54b28
Autor:
Julie Warin, Nicolas Vedrenne, Vivian Tam, Mengxia Zhu, Danqing Yin, Xinyi Lin, Bluwen Guidoux-D’halluin, Antoine Humeau, Luce Roseiro, Lily Paillat, Claire Chédeville, Caroline Chariau, Frank Riemers, Markus Templin, Jérôme Guicheux, Marianna A. Tryfonidou, Joshua W.K. Ho, Laurent David, Danny Chan, Anne Camus
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109018- (2024)
Summary: Understanding the emergence of human notochordal cells (NC) is essential for the development of regenerative approaches. We present a comprehensive investigation into the specification and generation of bona fide NC using a straightforward p
Externí odkaz:
https://doaj.org/article/4fbbade5e5f24b0385edeacb652fc23d
Autor:
Büşra Günay, Elizabeth Matthews, Jack Morgan, Marianna A. Tryfonidou, Radka Saldova, Abhay Pandit
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 8, Pp 321-335 (2023)
Abstract Degeneration of the intervertebral disc is an age‐related condition. It also accompanies the disappearance of the notochordal cells, which are remnants of the developmental stages of the nucleus pulposus (NP). Molecular changes such as ext
Externí odkaz:
https://doaj.org/article/a277ae4a05d344ca8e6de75ab1dc08ae
Autor:
Martijn Beukers, Guy C. M. Grinwis, Johannes C. M. Vernooij, Lisanne van derHoek, Anna R. Tellegen, Björn P. Meij, Stefanie Veraa, Dino Samartzis, Marianna A. Tryfonidou, Frances C. Bach
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Chronic low back pain, a leading contributor to disease burden worldwide, is often caused by intervertebral disc (IVD) degeneration. Modic changes (MCs) are MRI signal intensity changes due to lesions in vertebral bone marrow adja
Externí odkaz:
https://doaj.org/article/fb5d475e0b13418d8d7f2ea7a5d5e74d
Autor:
Rebecca J. Williams, Lisanne T. Laagland, Frances C. Bach, Lizzy Ward, Wilson Chan, Vivian Tam, Adel Medzikovic, Shaghayegh Basatvat, Lily Paillat, Nicolas Vedrenne, Joseph W. Snuggs, Deepani W. Poramba‐Liyanage, Judith A. Hoyland, Danny Chan, Anne Camus, Stephen M. Richardson, Marianna A. Tryfonidou, Christine L. Le Maitre
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Lineage‐tracing experiments have established that the central region of the mature intervertebral disc, the nucleus pulposus (NP), develops from the embryonic structure called “the notochord”. However, changes in the cells d
Externí odkaz:
https://doaj.org/article/dfa01fb81efe46eab3be07a579ca5024