Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Marianna A, Tryfonidou"'
Autor:
Imke Rudnik-Jansen, Jie Du, Nina Karssemakers-Degen, Anna R. Tellegen, Parvesh Wadhwani, Daniele Zuncheddu, Björn P. Meij, Jens Thies, Pieter Emans, Fetullah C. Öner, George Mihov, Joao Pedro Garcia, Anne S. Ulrich, Sibylle Grad, Marianna A. Tryfonidou, Hugo van Ingen, Laura B. Creemers
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Intradiscal drug delivery is a promising strategy for treating intervertebral disk degeneration (IVDD). Local degenerative processes and intrinsically low fluid exchange are likely to influence drug retention. Understanding their connection will enab
Externí odkaz:
https://doaj.org/article/e74ff26b3ae344bf99b69a5fc7b3d7c3
Autor:
Frank Niemeyer, Fabio Galbusera, Martijn Beukers, René Jonas, Youping Tao, Marion Fusellier, Marianna A. Tryfonidou, Cornelia Neidlinger‐Wilke, Annette Kienle, Hans‐Joachim Wilke
Publikováno v:
JOR Spine, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background Intervertebral disc degeneration is frequent in dogs and can be associated with symptoms and functional impairments. The degree of disc degeneration can be assessed on T2‐weighted MRI scans using the Pfirrmann classification sch
Externí odkaz:
https://doaj.org/article/c5243798e06b4187acb440048fa9f106
Autor:
Thomas Bitterli, David Schmid, Ladina Ettinger, Olga Krupkova, Frances C. Bach, Marianna A. Tryfonidou, Björn P. Meij, Antonio Pozzi, Frank Steffen, Karin Wuertz‐Kozak, Lucas A. Smolders
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background The regulation of inflammatory mediators in the degenerating intervertebral disc (IVD) and corresponding ligamentum flavum (LF) is a topic of emerging interest. The study aimed to investigate the expression of a broad array of inf
Externí odkaz:
https://doaj.org/article/a0130bc574964e6baf2eee7b83f54b28
Autor:
Irin Kwananocha, Joëll Magré, Amir Kamali, Femke Verseijden, Koen Willemsen, Yuntao Ji, Bart C. H. van der Wal, Ralph J. B. Sakkers, Marianna A. Tryfonidou, Björn P. Meij
Publikováno v:
Animals, Vol 14, Iss 16, p 2385 (2024)
The acetabular rim extension (ACE-X) implant is a custom-made three-dimensionally printed titanium device designed for the treatment of canine hip dysplasia. In this study, 34 dogs (61 hips) underwent ACE-X implantation, and assessments were conducte
Externí odkaz:
https://doaj.org/article/39c2311138974261998a9330c812f5c0
Autor:
Büşra Günay, Elizabeth Matthews, Jack Morgan, Marianna A. Tryfonidou, Radka Saldova, Abhay Pandit
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 8, Pp 321-335 (2023)
Abstract Degeneration of the intervertebral disc is an age‐related condition. It also accompanies the disappearance of the notochordal cells, which are remnants of the developmental stages of the nucleus pulposus (NP). Molecular changes such as ext
Externí odkaz:
https://doaj.org/article/a277ae4a05d344ca8e6de75ab1dc08ae
Autor:
Julie Warin, Nicolas Vedrenne, Vivian Tam, Mengxia Zhu, Danqing Yin, Xinyi Lin, Bluwen Guidoux-D’halluin, Antoine Humeau, Luce Roseiro, Lily Paillat, Claire Chédeville, Caroline Chariau, Frank Riemers, Markus Templin, Jérôme Guicheux, Marianna A. Tryfonidou, Joshua W.K. Ho, Laurent David, Danny Chan, Anne Camus
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109018- (2024)
Summary: Understanding the emergence of human notochordal cells (NC) is essential for the development of regenerative approaches. We present a comprehensive investigation into the specification and generation of bona fide NC using a straightforward p
Externí odkaz:
https://doaj.org/article/4fbbade5e5f24b0385edeacb652fc23d
Autor:
Martijn Beukers, Guy C. M. Grinwis, Johannes C. M. Vernooij, Lisanne van derHoek, Anna R. Tellegen, Björn P. Meij, Stefanie Veraa, Dino Samartzis, Marianna A. Tryfonidou, Frances C. Bach
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Chronic low back pain, a leading contributor to disease burden worldwide, is often caused by intervertebral disc (IVD) degeneration. Modic changes (MCs) are MRI signal intensity changes due to lesions in vertebral bone marrow adja
Externí odkaz:
https://doaj.org/article/fb5d475e0b13418d8d7f2ea7a5d5e74d
Autor:
Rebecca J. Williams, Lisanne T. Laagland, Frances C. Bach, Lizzy Ward, Wilson Chan, Vivian Tam, Adel Medzikovic, Shaghayegh Basatvat, Lily Paillat, Nicolas Vedrenne, Joseph W. Snuggs, Deepani W. Poramba‐Liyanage, Judith A. Hoyland, Danny Chan, Anne Camus, Stephen M. Richardson, Marianna A. Tryfonidou, Christine L. Le Maitre
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Background Lineage‐tracing experiments have established that the central region of the mature intervertebral disc, the nucleus pulposus (NP), develops from the embryonic structure called “the notochord”. However, changes in the cells d
Externí odkaz:
https://doaj.org/article/dfa01fb81efe46eab3be07a579ca5024
Autor:
Jie Du, João P. Garcia, Frances C. Bach, Anna R. Tellegen, Sibylle Grad, Zhen Li, René M. Castelein, Björn P. Meij, Marianna A. Tryfonidou, Laura B. Creemers
Publikováno v:
Journal of Orthopaedic Translation, Vol 37, Iss , Pp 23-36 (2022)
Background: Intervertebral disc (IVD) degeneration is suggested as a major cause of chronic low back pain (LBP). Intradiscal delivery of growth factors has been proposed as a promising strategy for IVD repair and regeneration. Previously, BMP-4 was s
Externí odkaz:
https://doaj.org/article/850513532fae49d98f7ddb56266e7ac3
Autor:
Celien A. M. Jacobs, Remco J. P. Doodkorte, S. Amir Kamali, Abdelrahman M. Abdelgawad, Samaneh Ghazanfari, Stefan Jockenhoevel, J. J. Chris Arts, Marianna A. Tryfonidou, Björn P. Meij, Keita Ito
Publikováno v:
JOR Spine, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Context Cervical disc replacement (CDR) aims to restore motion of the treated level to reduce the risk of adjacent segment disease (ASD) compared with spinal fusion. However, first‐generation articulating devices are unable to m
Externí odkaz:
https://doaj.org/article/c1b029a167b740f5840549b8a32073bc