Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marianna, Zolotovskaia"'
Autor:
Alexander Modestov, Marianna Zolotovskaia, Maria Suntsova, Galina Zakharova, Aleksander Seryakov, Ivana Jovcevska, Jernej Mlakar, Elena Poddubskaya, Aleksey Moisseev, Grigory Vykhodtsev, Sergey Roumiantsev, Maksim Sorokin, Victor Tkachev, Aleksander Simonov, Anton Buzdin
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Glioblastoma (GBM) is the most aggressive and lethal central nervous system (CNS) tumor. The treatment strategy is mainly surgery and/or radiation therapy, both combined with adjuvant temozolomide (TMZ) chemotherapy. Historically, methyla
Externí odkaz:
https://doaj.org/article/0cbfd8ce25624529b0c97414dc866f4a
Autor:
Maxim Sorokin, Marianna Zolotovskaia, Daniil Nikitin, Maria Suntsova, Elena Poddubskaya, Alexander Glusker, Andrew Garazha, Alexey Moisseev, Xinmin Li, Marina Sekacheva, David Naskhletashvili, Alexander Seryakov, Ye Wang, Anton Buzdin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background: Overall survival of advanced colorectal cancer (CRC) patients remains poor, and gene expression analysis could potentially complement detection of clinically relevant mutations to personalize CRC treatments. Methods: We performed
Externí odkaz:
https://doaj.org/article/f0e65dd2612144beba125d5e02bdbed1
Autor:
Marianna Zolotovskaia, Maks Kovalenko, Polina Pugacheva, Victor Tkachev, Alexander Simonov, Maxim Sorokin, Alexander Seryakov, Andrew Garazha, Nurshat Gaifullin, Marina Sekacheva, Galina Zakharova, Anton A. Buzdin
Publikováno v:
Proteomes, Vol 11, Iss 3, p 26 (2023)
Individual gene expression and molecular pathway activation profiles were shown to be effective biomarkers in many cancers. Here, we used the human interactome model to algorithmically build 7470 molecular pathways centered around individual gene pro
Externí odkaz:
https://doaj.org/article/ad117488a3bc4345bdbae550b0a3ed52
Autor:
Maxim Sorokin, Alexander Gorelyshev, Victor Efimov, Evgenia Zotova, Marianna Zolotovskaia, Elizaveta Rabushko, Denis Kuzmin, Alexander Seryakov, Dmitry Kamashev, Xinmin Li, Elena Poddubskaya, Maria Suntsova, Anton Buzdin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor mutation burden (TMB) is a well-known efficacy predictor for checkpoint inhibitor immunotherapies. Currently, TMB assessment relies on DNA sequencing data. Gene expression profiling by RNA sequencing (RNAseq) is another type of analysis that ca
Externí odkaz:
https://doaj.org/article/3accc6fa25814229934dc84dbeba498f
Autor:
Alexander Seryakov, Zaynab Magomedova, Maria Suntsova, Anastasia Prokofieva, Elizaveta Rabushko, Alexander Glusker, Lyudmila Makovskaia, Marianna Zolotovskaia, Anton Buzdin, Maxim Sorokin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Uterine leiomyosarcoma (UL) is a rare malignant tumor that develops from the uterine smooth muscle tissue. Due to the low frequency and lack of sufficient data from clinical trials there is currently no effective treatment that is routinely accepted
Externí odkaz:
https://doaj.org/article/45b634a9f6574fda8cb58a10d2a45069
Autor:
Dmitry Kamashev, Maksim Sorokin, Irina Kochergina, Aleksey Drobyshev, Uliana Vladimirova, Marianna Zolotovskaia, Igor Vorotnikov, Nina Shaban, Mikhail Raevskiy, Denis Kuzmin, Anton Buzdin
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06394- (2021)
Many patients fail to respond to EGFR-targeted therapeutics, and personalized diagnostics is needed to identify putative responders. We investigated 1630 colorectal and lung squamous carcinomas and 1357 normal lung and colon samples and observed huge
Externí odkaz:
https://doaj.org/article/9d100a741e0e405fad1b69f335f7585a
Autor:
Uliana Vladimirova, Pavel Rumiantsev, Marianna Zolotovskaia, Eugene Albert, Aleksander Abrosimov, Konstantin Slashchuk, Petr Nikiforovich, Olga Chukhacheva, Nurshat Gaifullin, Maria Suntsova, Galina Zakharova, Alexander Glusker, Daniil Nikitin, Andrew Garazha, Xinmin Li, Dmitriy Kamashev, Alexei Drobyshev, Irina Kochergina-Nikitskaya, Maxim Sorokin, Anton Buzdin
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06408- (2021)
DNA repair can prevent mutations and cancer development, but it can also restore damaged tumor cells after chemo and radiation therapy. We performed RNA sequencing on 95 human pathological thyroid biosamples including 17 follicular adenomas, 23 folli
Externí odkaz:
https://doaj.org/article/89654cc2c56142ac9048953d21263541
Autor:
Maxim Sorokin, Nicolas Borisov, Denis Kuzmin, Alexander Gudkov, Marianna Zolotovskaia, Andrew Garazha, Anton Buzdin
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Current methods of high-throughput molecular and genomic analyses enabled to reconstruct thousands of human molecular pathways. Knowledge of molecular pathways structure and architecture taken along with the gene expression data can help interrogatin
Externí odkaz:
https://doaj.org/article/36811fb3e32a4d05a783374ba070cfbe
Autor:
Julian Markovich Rozenberg, Margarita Kamynina, Maksim Sorokin, Marianna Zolotovskaia, Elena Koroleva, Kristina Kremenchutckaya, Alexander Gudkov, Anton Buzdin, Nicolas Borisov
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1072 (2022)
Metal ion homeostasis is fundamental for life. Specifically, transition metals iron, manganese and zinc play a pivotal role in mitochondrial metabolism and energy generation, anti-oxidation defense, transcriptional regulation and the immune response.
Externí odkaz:
https://doaj.org/article/9ebbf679d54e494b87c55ae0d9669ffa
Autor:
Alf Giese, Victor Tkachev, Andrew Garazha, Anton Buzdin, Alexey Moisseev, Alja Zottel, Ella Kim, Marianna Zolotovskaia, Sven R. Kantelhardt, Denis Kuzmin, Bettina Sprang, Sven-Ernö Bikar, Neja Šamec, Victor Efimov, Ivana Jovčevska, Maxim Sorokin
Publikováno v:
Cancers, vol. 13, no. 16, 4117, 2021.
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4117, p 4117 (2021)
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4117, p 4117 (2021)
Gliomas are the most common malignant brain tumors with high mortality rates. Recently we showed that the FREM2 gene has a role in glioblastoma progression. Here we reconstructed the FREM2 molecular pathway using the human interactome model. We asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52c926eeea9276f276c3414cdda023f
https://hdl.handle.net/20.500.12556/RUL-135973
https://hdl.handle.net/20.500.12556/RUL-135973
