Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Marianna, Inglese"'
Autor:
Amarnath Challapalli, Tara D. Barwick, Suraiya R. Dubash, Marianna Inglese, Matthew Grech-Sollars, Kasia Kozlowski, Henry Tam, Neva H. Patel, Mathias Winkler, Penny Flohr, Azeem Saleem, Amit Bahl, Alison Falconer, Johann S. De Bono, Eric O. Aboagye, Stephen Mangar
Publikováno v:
Molecules, Vol 28, Iss 24, p 8018 (2023)
Malignant transformation is characterised by aberrant phospholipid metabolism of cancers, associated with the upregulation of choline kinase alpha (CHKα). Due to the metabolic instability of choline radiotracers and the increasing use of late-imagin
Externí odkaz:
https://doaj.org/article/74674289d27f44588c3184f2bea4b18b
Autor:
Marianna Inglese, Neva Patel, Kristofer Linton-Reid, Flavia Loreto, Zarni Win, Richard J. Perry, Christopher Carswell, Matthew Grech-Sollars, William R. Crum, Haonan Lu, Paresh A. Malhotra, the Alzheimer’s Disease Neuroimaging Initiative, Eric O. Aboagye
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-16 (2022)
Inglese et al. develop a predictive model that computes multi-regional statistical morpho-functional mesoscopic traits from T1-weighted magnetic resonance imaging scans. Their model reliably discriminates people with Alzheimer’s disease-related pat
Externí odkaz:
https://doaj.org/article/516c8e439e694aad9272b31dd5159e63
Autor:
Yunqing Li, Marianna Inglese, Suraiya Dubash, Chris Barnes, Diana Brickute, Marta Costa Braga, Ning Wang, Alice Beckley, Kathrin Heinzmann, Louis Allott, Haonan Lu, Cen Chen, Ruisi Fu, Laurence Carroll, Eric O. Aboagye
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1246 (2021)
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotr
Externí odkaz:
https://doaj.org/article/d45310b8a4984fdbbf4cf37c689fdb94
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2022
Positron emission tomography (PET) can reveal metabolic activity in a voxelwise manner. PET analysis is commonly performed in a static manner by analyzing the standardized uptake value (SUV) obtained from the plateau region of PET acquisitions. A dyn
Autor:
Marianna, Inglese, Neva, Patel, Kristofer, Linton-Reid, Flavia, Loreto, Zarni, Win, Richard J, Perry, Christopher, Carswell, Matthew, Grech-Sollars, William R, Crum, Haonan, Lu, Paresh A, Malhotra, Gail, Li
Alzheimer's disease, the most common cause of dementia, causes a progressive and irreversible deterioration of cognition that can sometimes be difficult to diagnose, leading to suboptimal patient care.We developed a predictive model that computes mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67aff9a1a3ef401d67561c90b2cfb339
http://hdl.handle.net/10044/1/97726
http://hdl.handle.net/10044/1/97726
Autor:
Rohini Sharma, Haonan Lu, Paul D Tait, Neva H. Patel, Chandan Sanghera, William R. Crum, David J. Pinato, Suraiya Dubash, Eric O. Aboagye, Tara Barwick, Anthony Jen-Yu Chung, Marianna Inglese, Francesco Mauri
Publikováno v:
Journal of Nuclear Medicine. 61:1743-1748
Accurate disease monitoring is essential following transarterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) due to potential for profound adverse event and large variation in survival outcome. Post-treatment changes on conventional im
Autor:
Amarnath Challapalli, Suraiya Dubash, Rex Stanbridge, Pritesh Trivedi, Matthew Berry, Kasia Kozlowski, Conrad R. Lewanski, Frances Bowen, Marianna Inglese, Mubarik Arshad, Eric O. Aboagye, Tara Barwick, Francesco Mauri, Adil Al-Nahhas
Publikováno v:
Theranostics. 10:8677-8690
Purpose: The spatio-molecular distribution of choline and its metabolites in tumors is highly heterogeneous. Due to regulation of choline metabolism by hypoxic transcriptional signaling and other survival factors, we envisage that detection of such h
Autor:
Ning Wang, Chris P. Barnes, Suraiya Dubash, Diana Brickute, Cen Chen, Marta Braga, Eric O. Aboagye, Marianna Inglese, Yunqing Li, Kathrin Heinzmann, Ruisi Fu, Alice Beckley, Haonan Lu, Louis Allott, Laurence Carroll
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1246, p 1246 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1246, p 1246 (2021)
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276afc69ae2d9b74c0578b904c079290
http://hdl.handle.net/10044/1/90990
http://hdl.handle.net/10044/1/90990
Autor:
Tara Barwick, Lesley Honeyfield, Eric O. Aboagye, Adam D. Waldman, Matthew Grech-Sollars, Katherine Ordidge, Marianna Inglese
Publikováno v:
Neuroradiology
Inglese, M, Ordidge, K L, Honeyfield, L, Barwick, T D, Aboagye, E O, Waldman, A D & Grech-Sollars, M 2019, ' Reliability of dynamic contrast-enhanced magnetic resonance imaging data in primary brain tumours: a comparison of Tofts and shutter speed models ', Neuroradiology . https://doi.org/10.1007/s00234-019-02265-2
Inglese, M, Ordidge, K L, Honeyfield, L, Barwick, T D, Aboagye, E O, Waldman, A D & Grech-Sollars, M 2019, ' Reliability of dynamic contrast-enhanced magnetic resonance imaging data in primary brain tumours: a comparison of Tofts and shutter speed models ', Neuroradiology . https://doi.org/10.1007/s00234-019-02265-2
Purpose The purpose of this study is to investigate the robustness of pharmacokinetic modelling of DCE-MRI brain tumour data and to ascertain reliable perfusion parameters through a model selection process and a stability test. Methods DCE-MRI data o
Autor:
Suraiya, Dubash, Marianna, Inglese, Francesco, Mauri, Kasia, Kozlowski, Pritesh, Trivedi, Mubarik, Arshad, Amarnath, Challapalli, Tara, Barwick, Adil, Al-Nahhas, Rex, Stanbridge, Conrad, Lewanski, Matthew, Berry, Frances, Bowen, Eric O, Aboagye
Publikováno v:
Theranostics
Purpose: The spatio-molecular distribution of choline and its metabolites in tumors is highly heterogeneous. Due to regulation of choline metabolism by hypoxic transcriptional signaling and other survival factors, we envisage that detection of such h