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23. HOW GENES AND ENVIRONMENTS MODIFY INTERGENERATIONAL RISK FOR DEPRESSION – USING POLYGENIC SCORES TO TRANSLATE BETWEEN RODENTS AND HUMANS

Autor: van Dijk, Milenna, Malave, Lauren, Pokhvisneva, Irina, Patel, Sachin, Mariani, Madeline Butler, Kashyap, Pratik, Desai, Karan, Cha, Jiook, Gameroff, Marc, Posner, Jonathan E., Boldrini, Maura, Weissman, Myrna, Talati, Ardesheer, Anacker, Christoph, Silveira, Patricia Pelufo

Publikováno v: In European Neuropsychopharmacology October 2023 75 Supplement 1:S69-S69

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A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity.

Autor: Mosharov EV; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA.; New York State Psychiatric Institute, New York, NY, USA., Rosenberg AM; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA., Monzel AS; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA., Osto CA; Department of Medicine, Endocrinology, and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA., Stiles L; Department of Medicine, Endocrinology, and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA., Rosoklija GB; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Dwork AJ; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, USA., Bindra S; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA., Zhang Y; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Fujita M; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Mariani MB; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Bakalian M; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Sulzer D; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA.; New York State Psychiatric Institute, New York, NY, USA.; Departments of Neurology and Pharmacology, Columbia University Irving Medical Center, New York, NY, USA; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., De Jager PL; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Menon V; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Shirihai OS; Department of Medicine, Endocrinology, and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA., Mann JJ; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Underwood M; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Boldrini M; New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Division of Molecular Imaging and Neuropathology, Columbia University Irving Medical Center, New York, NY, USA., Thiebaut de Schotten M; Brain Connectivity and Behavior Laboratory, Paris, France; Groupe d'Imagerie Neurofonctionnelle, Institut des Maladies Neurodégénératives-UMR 5293, CNRS, CEA University of Bordeaux, France., Picard M; Department of Psychiatry, Divisions of Molecular Therapeutics and Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA.; New York State Psychiatric Institute, New York, NY, USA.; Department of Neurology, H. Houston Merritt Center, Columbia Translational Neuroscience Initiative, Columbia University Irving Medical Center, New York, NY, USA.; Robert N Butler Columbia Aging Center, Columbia University Mailman School of Public Health, New York, NY, USA.

Publikováno v: Research square [Res Sq] 2024 Mar 22. Date of Electronic Publication: 2024 Mar 22.