Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mariangela Panetta"'
Autor:
Ornella Franzese, Belinda Palermo, Giuseppe Frisullo, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Riccardo Taje, Paolo Visca, Paola Nisticò
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Improving cancer immunotherapy efficacy hinges on identifying key T-cell populations critical for tumor control and response to Immune Checkpoint Blockade (ICB). We have recently reported that while the co-expression of PD-1 and CD28 is associated wi
Externí odkaz:
https://doaj.org/article/4a3fe000f0ec40e5ac1a176751a5d0fd
Autor:
Francesca Di Modugno, Anna Di Carlo, Sheila Spada, Belinda Palermo, Lorenzo D'Ambrosio, Daniel D'Andrea, Gaia Morello, Beatrice Belmonte, Isabella Sperduti, Vittoria Balzano, Enzo Gallo, Roberta Melchionna, Mariangela Panetta, Giulia Campo, Francesca De Nicola, Frauke Goeman, Barbara Antoniani, Silvia Carpano, Gianmaria Frigè, Sarah Warren, Filippo Gallina, Diether Lambrechts, Jieyi Xiong, Benjamin G. Vincent, Nathan Wheeler, Dante S. Bortone, Federico Cappuzzo, Francesco Facciolo, Claudio Tripodo, Paolo Visca, Paola Nisticò
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105003- (2024)
Summary: Background: Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes tissue-specific splicing, pro
Externí odkaz:
https://doaj.org/article/5fd739eb5c1748ce8a0ed4de3fe1985a
Autor:
Belinda Palermo, Ornella Franzese, Giuseppe Frisullo, Lorenzo D’Ambrosio, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Francesca De Nicola, Frauke Goeman, Filippo Gallina, Paolo Visca, Francesco Facciolo, Paola Nisticò
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-26 (2023)
Abstract Background Immune checkpoint blockade (ICB) has significantly prolonged survival of non-small cell lung cancer (NSCLC) patients, although most patients develop mechanisms of resistance. Recently single-cell RNA-sequencing (scRNA-Seq) reveale
Externí odkaz:
https://doaj.org/article/571ea82633d4428bb111cb168f3d2393
Autor:
Belinda Palermo, Marta Bottero, Mariangela Panetta, Adriana Faiella, Isabella Sperduti, Serena Masi, Giuseppe Frisullo, Maria Laura Foddai, Iole Cordone, Paola Nisticò, Giuseppe Sanguineti
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe impact of radiotherapy (RT) on immune cell status in prostate cancer (PCa) is only partially determined. The aim of this study was to assess the effect of different RT strategies on peripheral B, T, and Natural killer (NK) lymphocytes at
Externí odkaz:
https://doaj.org/article/e599e4d421d94547bf7d4c518a65f5cb
Autor:
Sarah Warren, Paola Nisticò, Federico Cappuzzo, Federica Marchesi, Isabella Sperduti, Silvia Carpano, Francesca De Nicola, Frauke Goeman, Lorenzo D'Ambrosio, Vanesa Gregorc, Claudio Tripodo, Vincenzo Russo, Paolo Visca, Francesca Paolini, Paola Trono, Annalisa Tocci, Belinda Palermo, Anna Di Carlo, Daniel D'Andrea, Francesca Di Modugno, Giacomo Corleone, Mariangela Panetta, Silvia Baldari, Paolo Zucali
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint blockade (ICB) is a crucial step in improving immunotherapy efficacy. Among the pathways th
Externí odkaz:
https://doaj.org/article/fd3fa3f807bf4ff6ad2b89290cb99193
Autor:
Mariangela Panetta, Alessandra Bianchetti, Nathasha Samali Udugampolage, Jacopo Taurino, Rosario Caruso, Alessandro Pini, Edward Callus
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1e6fa8aeacf240edb631beb56c133668
Autor:
Nathasha Udugampolage, Rosario Caruso, Mariangela Panetta, Edward Callus, Federica Dellafiore, Arianna Magon, Susan Marelli, Alessandro Pini
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252864 (2021)
IntroductionThe structural validity and reliability of the Short-Form Health Survey 12 (SF-12) has not yet been tested in adults with the Marfan syndrome (MFS). This gap could undermine an evidence-grounded practice and research, especially consideri
Externí odkaz:
https://doaj.org/article/d486e1bbdeb44579b50a2a16c2b95758
Autor:
Belinda Palermo, Ornella Franzese, Cosmo Di Donna, Mariangela Panetta, Concetta Quintarelli, Isabella Sperduti, Novella Gualtieri, Maria Laura Foddai, Enrico Proietti, Virginia Ferraresi, Gennaro Ciliberto, Paola Nisticò
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
We have recently described that DNA-damage inducing drug DTIC, administered before peptide (Melan-A and gp100)-vaccination, improves anti-tumor CD8+ Melan-A-specific T-cell functionality, enlarges the Melan-A+ TCR repertoire and impacts the overall s
Externí odkaz:
https://doaj.org/article/68373cd86cff4bdc93b8465e055a25a6
Autor:
Eleonora Timperi, Chiara Focaccetti, Daniela Gallerano, Mariangela Panetta, Sheila Spada, Enzo Gallo, Paolo Visca, Federico Venuta, Daniele Diso, Arsela Prelaj, Flavia Longo, Francesco Facciolo, Paola Nisticò, Vincenzo Barnaba
Publikováno v:
OncoImmunology, Vol 6, Iss 7 (2017)
IL-18 is an inflammasome-related cytokine, member of the IL-1 family, produced by a wide range of cells in response to signals by several pathogen- or damage-associated molecular patterns. It can be highly represented in tumor patients, but its relev
Externí odkaz:
https://doaj.org/article/3a3aab95fc704fc39842f0e2c0df917d
Autor:
Gian Paolo Spinelli, Rosalba Caccavale, Carmela Martire, Ilenia Cammarata, Paolo Visca, Sheila Spada, Felice Giangaspero, Paola Nisticò, Silvia Piconese, Silverio Tomao, Chiara Focaccetti, Fabiana Letizia Cecere, Gabriella Girelli, Julio Rodrigo Giròn Berrìos, Flavia Longo, Federica Buzzacchino, Carmine Mancone, Marino Paroli, Giovanna Peruzzi, Vincenzo Barnaba, Marta Buccilli, Mariangela Panetta, Alessio Grimaldi, Nicoletta D'Alessandris, Francesco Facciolo
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology
Communications Biology
Here, we developed an unbiased, functional target-discovery platform to identify immunogenic proteins from primary non-small cell lung cancer (NSCLC) cells that had been induced to apoptosis by cisplatin (CDDP) treatment in vitro, as compared with th