Fluvoxamine alters the activity of energy metabolism enzymes in the brain

Autor: Gabriela K. Ferreira, Mariane R. Cardoso, Isabela C. Jeremias, Cinara L. Gonçalves, Karolina V. Freitas, Rafaela Antonini, Giselli Scaini, Gislaine T. Rezin, João Quevedo, Emilio L. Streck

Publikováno v: Brazilian Journal of Psychiatry, Vol 36, Iss 3, Pp 220-226 (2014)

Objective: Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by modulating brain energy metabolism. Thus, we evaluated the activity of Krebs cycle enzy

Externí odkaz: https://doaj.org/article/45e4a5b95c224e43acc4bf714b9b2088

Fluvoxamine alters the activity of energy metabolism enzymes in the brain

Autor: Karolina V. Freitas, Mariane R. Cardoso, João Quevedo, Cinara L. Gonçalves, Emilio L. Streck, Rafaela Antonini, Isabela C. Jeremias, Gislaine T. Rezin, Gabriela K. Ferreira, Giselli Scaini

Publikováno v: Brazilian Journal of Psychiatry, Vol 36, Iss 3, Pp 220-226 (2014)
Revista Brasileira de Psiquiatria, Volume: 36, Issue: 3, Pages: 220-226, Published: 17 MAR 2014
Brazilian Journal of Psychiatry v.36 n.3 2014
Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Associação Brasileira de Psiquiatria (ABP)
instacron:ABP

Objective: Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by modulating brain energy metabolism. Thus, we evaluated the activity of Krebs cycle enzy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1719944650f8eeb38c6f6555085d5a0
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462014000300220&lng=en&tlng=en

Effects of acute and chronic administration of fenproporex on DNA damage parameters in young and adult rats

Autor: Daniela Dimer Leffa, Gislaine T. Rezin, João Quevedo, Gabriela K. Ferreira, Mariane R. Cardoso, Isabela C. Jeremias, Gabriela D. Borges, Cinara L. Gonçalves, Samira S. Valvassori, Vanessa Moraes de Andrade, Bruno N. Bristot, Emilio L. Streck, Bruna Juliete Pazini Munhoz

Publikováno v: Molecular and Cellular Biochemistry. 380:171-176

Obesity is a chronic and multifactorial disease, whose prevalence is increasing in many countries. Pharmaceutical strategies for the treatment of obesity include drugs that regulate food intake, thermogenesis, fat absorption, and fat metabolism. Fenp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8a7b804cc44770d09e36ff52c951db
https://doi.org/10.1007/s11010-013-1670-2

Differential effects of escitalopram administration on metabolic parameters of cortical and subcortical brain regions of Wistar rats

Autor: Isabela C. Jeremias, Emilio L. Streck, Gislaine T. Rezin, João Quevedo, Alexandra I. Zugno, Gabriela K. Ferreira, Milena Carvalho-Silva, Cinara L. Gonçalves, Mariane R. Cardoso

Publikováno v: Acta Neuropsychiatrica. 24:147-154

Objective:Considering that mitochondria may be drug targets and some characteristics of drug–mitochondria interactions may still be misjudged because of the difficulty in foreseeing and understanding all possible implications of the complex pathoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a71f4d0b2aa8328652f14074b31b367
https://doi.org/10.1111/j.1601-5215.2011.00592.x

Fenproporex increases locomotor activity and alters energy metabolism, and mood stabilizers reverse these changes: a proposal for a new animal model of mania

Autor: Emilio L. Streck, Wilson R. Resende, Mariane R. Cardoso, Gislaine T. Rezin, Camila B. Furlanetto, Roger B. Varela, Gabriela K. Ferreira, Giselli Scaini, João Quevedo, Isabela C. Jeremias, Cinara L. Gonçalves, Samira S. Valvassori

Publikováno v: Molecular neurobiology. 49(2)

Fenproporex (Fen) is converted in vivo into amphetamine, which is used to induce mania-like behaviors in animals. In the present study, we intend to present a new animal model of mania. In order to prove through face, construct, and predictive validi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc62a659b137c5f86898dabf63de6386
https://pubmed.ncbi.nlm.nih.gov/24126971