Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mariane M A Stefani"'
Autor:
Rafael Silva Gama, Márcio Luís Moreira de Souza, Euzenir Nunes Sarno, Milton Ozório de Moraes, Aline Gonçalves, Mariane M A Stefani, Raúl Marcel González Garcia, Lucia Alves de Oliveira Fraga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007400 (2019)
BackgroundEarly detection of Mycobacterium leprae is a key strategy for disrupting the transmission chain of leprosy and preventing the potential onset of physical disabilities. Clinical diagnosis is essential, but some of the presented symptoms may
Externí odkaz:
https://doaj.org/article/8c4b61adf8824a6e83728baba4f43d6b
Autor:
Maurício Barcelos Costa, Emerith Mayra Hungria, Aline Araújo Freitas, Ana Lúcia O M Sousa, Juliano Jampietro, Fernando A Soares, Mariane M A Stefani
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0196853 (2018)
Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin and peripheral nerves especially during immuno-inflammatory episodes known as type 1/T1R and type 2/T2R reactions. This study investigated the in situ express
Externí odkaz:
https://doaj.org/article/e531f6fef3824110b145038d309c3443
Autor:
Mariane M A Stefani, Charlotte Avanzi, Samira Bührer-Sékula, Andrej Benjak, Chloé Loiseau, Pushpendra Singh, Maria A A Pontes, Heitor S Gonçalves, Emerith M Hungria, Philippe Busso, Jérémie Piton, Maria I S Silveira, Rossilene Cruz, Antônio Schetinni, Maurício B Costa, Marcos C L Virmond, Suzana M Diorio, Ida M F Dias-Baptista, Patricia S Rosa, Masanori Matsuoka, Maria L F Penna, Stewart T Cole, Gerson O Penna
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005598 (2017)
Since leprosy is both treated and controlled by multidrug therapy (MDT) it is important to monitor recurrent cases for drug resistance and to distinguish between relapse and reinfection as a means of assessing therapeutic efficacy. All three objectiv
Externí odkaz:
https://doaj.org/article/91540a58ac934e209d0d7e74859d55f7
Autor:
Vinicius M Fava, Jeremy Manry, Aurélie Cobat, Marianna Orlova, Nguyen Van Thuc, Milton O Moraes, Carolinne Sales-Marques, Mariane M A Stefani, Ana Carla P Latini, Andrea F Belone, Vu Hong Thai, Laurent Abel, Alexandre Alcaïs, Erwin Schurr
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006637 (2017)
Leprosy Type-1 Reactions (T1Rs) are pathological inflammatory responses that afflict a sub-group of leprosy patients and result in peripheral nerve damage. Here, we employed a family-based GWAS in 221 families with 229 T1R-affect offspring with stepw
Externí odkaz:
https://doaj.org/article/c055f3b3c45441308fad25fe8cb6774b
Autor:
Flavia Divino, Andre de Lima Guerra Corado, Felipe Gomes Naveca, Mariane M A Stefani, Gonzalo Bello
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162112 (2016)
The Human immunodeficiency virus type-1 (HIV-1) epidemic in Brazil is mainly driven by the subtype B pandemic lineage (BPANDEMIC), while Caribbean non-pandemic subtype B clades (BCAR) seem to account for a very low fraction of HIV-infections in this
Externí odkaz:
https://doaj.org/article/550cbd3f6fc44100be52a366473ab567
Autor:
Marcos Virmond, Marcelo Távora Mira, Gerson Oliveira Penna, Rossilene Conceição da Silva Cruz, Samira Bührer-Sékula, Heitor de Sá Gonçalves, Ida Maria Foschiani Dias-Baptista, Maria Araci de Andrade Pontes, Priscila Verchai Uaska Sartori, Mariane M. A. Stefani, Maria Lúcia Fernandes Penna, Patrícia Sammarco Rosa, Vinicius M. Fava
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-5 (2020)
Scientific Reports
Scientific Reports
Host genetic susceptibility to leprosy has been intensively investigated over the last decades; however, there are no studies on the role of genetic variants in disease recurrence. A previous initiative identified three recurrent cases of leprosy for
Autor:
Claudia M M, Abrahim, Victor, Py-Daniel, Sergio L B, Luz, Nelson A, Fraiji, Mariane M A, Stefani
Publikováno v:
Transfusion. 59(3)
In the Brazilian Amazon, the filarial nematode Mansonella ozzardi co-exists with malaria parasites and thick blood smear microscopy is considered the diagnostic gold standard. Transfusion of M. ozzardi microfilariae does not establish new infections,
Autor:
Gerson Oliveira Penna, Celina M. T. Martelli, Mariane M. A. Stefani, Vanize O. Macedo, Maria de Fátima Maroja, Aiçar Chaul
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 80, Iss 5, Pp 511-522 (2005)
FUNDAMENTOS: A hanseníase persiste como problema de saúde pública, e episódios de ENH são eventos agudos que ocorrem antes, durante e após PQT. Na última década, o uso da talidomida como agente imunomodulador foi expandido a outras doenças.
Autor:
Ana Lucia O M, Sousa, Mariane M A, Stefani, Gisner A S, Pereira, Mauricio B, Costa, Paula F, Rebello, Maria Katia, Gomes, Kazue, Narahashi, Thomas P, Gillis, James L, Krahenbuhl, Celina M T, Martelli
Publikováno v:
The American journal of tropical medicine and hygiene. 77(5)
Leprosy affects skin and peripheral nerves, and acute inflammatory type 1 reactions (reversal reaction) can cause neurologic impairment and disabilities. Single skin lesion paucibacillary leprosy volunteers (N = 135) recruited in three Brazilian ende
Autor:
Gisner A S, Pereira, Mariane M A, Stefani, João A, Araújo Filho, Luís Carlos S, Souza, Germana P, Stefani, Celina M T, Martelli
Publikováno v:
The American journal of tropical medicine and hygiene. 71(5)
Co-infections with human immunodeficiency virus (HIV) and Mycobacterium leprae represent unique opportunities to investigate the interaction of both pathogens. We determined the immunologic, virologic, and histopathologic characteristics of 22 co-inf