Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mariane B Melo"'
Autor:
Anannya Bhattacharya, Lonzaric Jan, Olga Burlak, Jilong Li, Ghanshyam Upadhyay, Katherine Williams, Jinhui Dong, Harrison Rohrer, Michelle Pynn, Andrew Simon, Nathan Kuhlmann, Sergei Pustylnikov, Mariane B. Melo, Antu K. Dey
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Varicella zoster virus (VZV) is a highly contagious human herpes virus responsible for causing chickenpox (varicella) and shingles (herpes zoster). Despite the approval of a highly effective vaccine, Shingrix®, the global incidence of herpe
Externí odkaz:
https://doaj.org/article/275e736cb31442479d18b298d31e253b
Autor:
Mariane B Melo, Quynh P Nguyen, Cynthia Cordeiro, Musa A Hassan, Ninghan Yang, Renée McKell, Emily E Rosowski, Lindsay Julien, Vincent Butty, Marie-Laure Dardé, Daniel Ajzenberg, Katherine Fitzgerald, Lucy H Young, Jeroen P J Saeij
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003779 (2013)
Most isolates of Toxoplasma from Europe and North America fall into one of three genetically distinct clonal lineages, the type I, II and III lineages. However, in South America these strains are rarely isolated and instead a great variety of other s
Externí odkaz:
https://doaj.org/article/a69600aab9ce4abca8982fa272bff50b
Autor:
Felipe Lelis, Laura A. Byk, Sergei Pustylnikov, Vivian Nguyen, Brandon Nguyen, Malorie Nitz, Prutha Tarte, Kunal Tungare, Jilong Li, Saikat Manna, Sampa Maiti, Dhwani H. Mehta, Narendran Sekar, Diana M. Posadas, Himanshu Dhamankar, Jeffrey A. Hughes, Lorenzo Aulisa, Amin Khan, Mariane B. Melo, Antu K. Dey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Several COVID-19 vaccines, some more efficacious than others, are now available and deployed, including multiple mRNA- and viral vector-based vaccines. With the focus on creating cost-effective solutions that can reach the low- and medium- i
Externí odkaz:
https://doaj.org/article/5cd8b9585ddd48ba870d45a8620ef89e
Autor:
Wendy Niedelman, Daniel A Gold, Emily E Rosowski, Joris K Sprokholt, Daniel Lim, Ailan Farid Arenas, Mariane B Melo, Eric Spooner, Michael B Yaffe, Jeroen P J Saeij
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002784 (2012)
The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell that manipulate the immune response allowing it to establish a chronic infection. Crosses between the types I, II and III strains, which are prevalent
Externí odkaz:
https://doaj.org/article/8d15070ac0ea4b4a99ca429118b77d59
Autor:
Mariane B Melo, Pia Kasperkovitz, Anna Cerny, Stephanie Könen-Waisman, Evelyn A Kurt-Jones, Egil Lien, Bruce Beutler, Jonathan C Howard, Douglas T Golenbock, Ricardo T Gazzinelli
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001071 (2010)
UNC93B1 associates with Toll-Like Receptor (TLR) 3, TLR7 and TLR9, mediating their translocation from the endoplasmic reticulum to the endolysosome, hence allowing proper activation by nucleic acid ligands. We found that the triple deficient '3d' mic
Externí odkaz:
https://doaj.org/article/019e1088e0dc48ad9a82bf36bcfa865c
Autor:
Kristen A. Rodrigues, Christopher A. Cottrell, Jon M. Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y. H. Chang, Parisa Yousefpour, Mariane B. Melo, William R. Schief, Darrell J. Irvine
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract In the ongoing effort to develop a vaccine against HIV, vaccine approaches that promote strong germinal center (GC) responses may be critical to enable the selection and affinity maturation of rare B cell clones capable of evolving to produc
Externí odkaz:
https://doaj.org/article/41280b26b64f4887a8b93d75737a93e1
Autor:
Antonio E. Barberio, Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo, Heikyung Suh, Robert A. Weinberg, Darrell J. Irvine, Paula T. Hammond
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Ovarian cancer is especially deadly, challenging to treat, and has proven refractory to known immunotherapies. Cytokine therapy is an attractive strategy to drive a proinflammatory immune response in immunologically cold tumors such as many
Externí odkaz:
https://doaj.org/article/da7a5559c1a94ad19eb3527ed8b1cd25
Autor:
Byungji, Kim, Ryan R, Hosn, Tanaka, Remba, Dongsoo, Yun, Na, Li, Wuhbet, Abraham, Mariane B, Melo, Manuel, Cortes, Bridget, Li, Yuebao, Zhang, Yizhou, Dong, Darrell J, Irvine
Publikováno v:
Journal of Controlled Release. 353:241-253
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs form
Autor:
Eric L. Dane, Alexis Belessiotis-Richards, Coralie Backlund, Jianing Wang, Kousuke Hidaka, Lauren E. Milling, Sachin Bhagchandani, Mariane B. Melo, Shengwei Wu, Na Li, Nathan Donahue, Kaiyuan Ni, Leyuan Ma, Masanori Okaniwa, Molly M. Stevens, Alfredo Alexander-Katz, Darrell J. Irvine
Publikováno v:
Nature Materials. 21:710-720
Activation of the innate immune STimulator of INterferon Genes (STING) pathway potentiates antitumour immunity, but systemic delivery of STING agonists to tumours is challenging. We conjugated STING-activating cyclic dinucleotides (CDNs) to PEGylated
Autor:
Darrell J. Irvine, Bradley L. Pentelute, Sylvie Le Gall, Na Li, Angela Q. Zhang, Mariane B. Melo, Wuhbet Abraham, Simon Liang, Jens Dinter, Mark R. Karver, Chensu Wang, Naveen K. Mehta, Rebecca L. Holden, Kelly D. Moynihan
Captions for Supplementary Figures and Supplementary Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c0dc4fe26ab57c9073c671506e52ae
https://doi.org/10.1158/2326-6066.22539502.v1
https://doi.org/10.1158/2326-6066.22539502.v1