Výsledky vyhledávání - "Mariana de Napoles"

Akademický článek

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.

Autor: Mariana de Napoles, Tatyana Nesterova, Neil Brockdorff

Publikováno v: PLoS ONE, Vol 2, Iss 9, p e860 (2007)

The inactive X chromosome characteristic of female somatic lineages is reactivated during development of the female germ cell lineage. In mouse, analysis of protein products of X-linked genes and/or transgenes located on the X chromosome has indicate

Externí odkaz: https://doaj.org/article/ca9e41db053146f79879eb2a296cde0f

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Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells

Autor: Tatyana B. Nesterova, Neil Brockdorff, Mariana de Napoles

Publikováno v: PLoS ONE, Vol 2, Iss 9, p e860 (2007)
PLoS ONE

Background The inactive X chromosome characteristic of female somatic lineages is reactivated during development of the female germ cell lineage. In mouse, analysis of protein products of X-linked genes and/or transgenes located on the X chromosome h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ce44e8731694e00631379a9f536063
http://europepmc.org/articles/PMC1959243?pdf=render

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Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

Autor: Neil Brockdorff, Rika Wakao, Haruhiko Koseki, Miguel Vidal, Jacqueline E. Mermoud, Y. Amy Tang, Arie P. Otte, Ruth Appanah, Mitusuhiro Endoh, Mariana de Napoles, Tatyana B. Nesterova, José C. R. Silva

Publikováno v: Developmental Cell, 7, 663-676. Cell Press
Digital.CSIC. Repositorio Institucional del CSIC
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In many higher organisms, 5%-15% of histone H2A is ubiquitylated at lysine 119 (uH2A). The function of this modification and the factors involved in its establishment, however, are unknown. Here we demonstrate that uH2A occurs on the inactive X chrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7deb9f2a87625590f6cdcc66ac31243d
https://dare.uva.nl/personal/pure/en/publications/polycomb-group-proteins-ring1ab-link-ubiquitylation-of-histone-h2a-to-heritable-gene-silencing-and-x-inactivation(687e2dca-4213-4581-aedf-2fe1a85ac451).html

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