Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mariana Temido‐Ferreira"'
Autor:
Ana Chegão, Mariana Guarda, Bruno M. Alexandre, Liana Shvachiy, Mariana Temido-Ferreira, Inês Marques-Morgado, Bárbara Fernandes Gomes, Rune Matthiesen, Luísa V. Lopes, Pedro R. Florindo, Ricardo A. Gomes, Patrícia Gomes-Alves, Joana E. Coelho, Tiago Fleming Outeiro, Hugo Vicente Miranda
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Alpha-synuclein (aSyn) is a central player in the pathogenesis of synucleinopathies due to its accumulation in typical protein aggregates in the brain. However, it is still unclear how it contributes to neurodegeneration. Type-2 diabetes mel
Externí odkaz:
https://doaj.org/article/505e44be1dd441bfb7ad630258f5cddb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
In vitro neuronal cultures are extensively used in the field of neurosciences as they represent an accessible experimental tool for neuronal genetic manipulation, time-lapse imaging, and drug screening. Optimizing the cultivation of rodent primary ne
Externí odkaz:
https://doaj.org/article/d3df59d70a284a13b0a5ceb5067f77ea
Autor:
Paula A. Pousinha, Xavier Mouska, Daniela Bianchi, Mariana Temido-Ferreira, Joana Rajão-Saraiva, Rui Gomes, Sebastian P. Fernandez, Ana Rita Salgueiro-Pereira, Carine Gandin, Elisabeth F. Raymond, Jacques Barik, Romain Goutagny, Ingrid Bethus, Luisa V. Lopes, Michele Migliore, Hélène Marie
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 317-331.e5 (2019)
Summary: There is a growing consensus that Alzheimer's disease (AD) involves failure of the homeostatic machinery, which underlies the firing stability of neural circuits. What are the culprits leading to neuron firing instability? The amyloid precur
Externí odkaz:
https://doaj.org/article/90855fdcacba470a93f8234bea3604cb
Autor:
Joana Rajão‐Saraiva, Jade Dunot, Aurore Ribera, Mariana Temido‐Ferreira, Joana E. Coelho, Svenja König, Sébastien Moreno, Francisco J. Enguita, Michael Willem, Stefan Kins, Hélène Marie, Luísa V. Lopes, Paula A. Pousinha
Publikováno v:
Aging Cell. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166af80542ef186ea88b1497f4ce61b1
https://doi.org/10.1111/acel.13778
https://doi.org/10.1111/acel.13778
Autor:
Joana Rajao-Saraiva, Mariana Temido-Ferreira, Joana E Coelho, Aurore Ribera, Sebastien Moreno, Michael Willem, Helene Marie, Luisa V. Lopes, Paula A Pousinha
N-methyl-D-aspartate receptors (NMDARs) are critical for the maturation and plasticity of glutamatergic synapses. In the hippocampus, NMDARs mainly contain GluN2A and/or GluN2B regulatory subunits. The amyloid precursor protein (APP) has emerged as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3737928da297f6b3bbadd5a82286c561
https://doi.org/10.1101/2022.07.20.500736
https://doi.org/10.1101/2022.07.20.500736
Publikováno v:
Frontiers in Molecular Neuroscience
In vitro neuronal cultures are extensively used in the field of neurosciences as they represent an accessible experimental tool for neuronal genetic manipulation, time-lapse imaging, and drug screening. Optimizing the cultivation of rodent primary ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262fef87a1fcae46aae0ea9d342a2c34
https://pubmed.ncbi.nlm.nih.gov/35774868
https://pubmed.ncbi.nlm.nih.gov/35774868
Autor:
Bruno M. Alexandre, Ana Chegão, Mariana Guarda, Rune Matthiesen, Tiago F. Outeiro, Ricardo Anjos-Gomes, Mariana Temido-Ferreira, Patrícia Gomes-Alves, Luísa V. Lopes, Bárbara Fernandes Gomes, Joana E. Coelho, Inês Marques-Morgado, Pedro Florindo, Liana Shvachiy, Hugo Vicente Miranda
Alpha-synuclein (aSyn) is assumed to be a central player in the pathogenesis of synucleinopathies due to its accumulation in typical protein aggregates in the brain. However, it is still unclear how it contributes to neurodegeneration. Type-2 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477cc022cc0192baac0e9e89f3906141
https://doi.org/10.1101/2021.08.24.457507
https://doi.org/10.1101/2021.08.24.457507
Publikováno v:
Clinical Genetics and Genomics of Aging ISBN: 9783030409548
Aging has been extensively associated with cognitive decline and synaptic dysfunction. Hippocampus has a key role in learning and memory, and undergoes structural and functional alterations upon aging process, despite the preservation of primary hipp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf24ab26652a4f65916951ac25b7640
https://doi.org/10.1007/978-3-030-40955-5_3
https://doi.org/10.1007/978-3-030-40955-5_3
Autor:
Bruno Silva-Santos, Emilie Faivre, Gitta Stockinger, David Blum, Sara Silva Pereira, Tommy Regen, Ari Waisman, Julie C. Ribot, Joana E. Coelho, Mariana Temido-Ferreira, Luc Buée, Kevin Carvalho, Paula A. Pousinha, Helena C. Brigas, Rui Gomes, Victoria Gomez, Ines Morgado, Miguel Ribeiro, Luísa V. Lopes, Sara Omenetti
Publikováno v:
Biological Psychiatry. 89:S64-S65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9376c7ed4f2e43e3aacb91e140d8efe
https://doi.org/10.1016/j.biopsych.2021.02.176
https://doi.org/10.1016/j.biopsych.2021.02.176
Autor:
Joana E. Coelho, Tiago F. Outeiro, Mariana Temido-Ferreira, Inga Zerr, Jeong-Seop Rhee, Matthias Schmitz, Éva M. Szegö, Sandra H. Vaz, Diana G. Ferreira, Vânia L. Batalha, Hugo Vicente Miranda, Luísa V. Lopes, Inês Marques-Morgado
Publikováno v:
Nature reviews / Neuroscience 20(11), 1569-1579 (2017). doi:10.1038/nn.4648
Nature Neuroscience
Nature Neuroscience
© 2017 Nature America, Inc., part of Springer Nature. All rights reserved.
Synucleinopathies, such as Parkinson's disease and dementia with Lewy bodies, are neurodegenerative disorders that are characterized by the accumulation of α-synuclein
Synucleinopathies, such as Parkinson's disease and dementia with Lewy bodies, are neurodegenerative disorders that are characterized by the accumulation of α-synuclein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a137a74503d7ee4176a5166446ddb
https://doi.org/10.1038/nn.4648
https://doi.org/10.1038/nn.4648