Analysis of mitochondrial enzymatic activity in blood lymphomonocyte fractions during infection with different Trypanosoma cruzi strains

Autor: Alejandra L. Báez, María S. Lo Presti, Paola C. Bazán, Mariana Strauss, Daniela A. Velázquez López, Noemí Miler, Héctor W. Rivarola, Patricia A. Paglini-Oliva

Publikováno v: Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020)

ABSTRACT Proinflammatory and inflammatory mediators induced by Trypanosoma cruzi infection increase the oxidative stress, generating toxicity for cells targeting mitochondria of different tissues. We studied the activity of citrate synthase and compl

Externí odkaz: https://doaj.org/article/d5bcd695879c461b8ce1105bfd0c5813

Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations.

Autor: Mariana Strauss, Marialbert Acosta-Herrera, Alexia Alcaraz, Desiré Casares-Marfil, Pau Bosch-Nicolau, María Silvina Lo Presti, Israel Molina, Clara Isabel González, Chagas Genetics CYTED Network, Javier Martín

Publikováno v: PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007859 (2019)

Host genetic factors have been suggested to play an important role in the susceptibility to Chagas disease. Given the influence of interleukin 18 (IL-18) in the development of the disease, in the present study, we analyzed three IL18 genetic variants

Externí odkaz: https://doaj.org/article/6abf07e1a57f42f29f31d7336730e2c8

Differential tissue distribution of discrete typing units after drug combination therapy in experimental

Autor: Mariana, Strauss, M Silvina, Lo Presti, Juan C, Ramírez, P Carolina, Bazán, Daniela A, Velázquez López, Alejandra L, Báez, Patricia A, Paglini, Alejandro G, Schijman, Héctor W, Rivarola

Publikováno v: Parasitology. 148(13)

The aim of the present work was to evaluate the distribution of the different clones of the parasite prevailing after treatment with benznidazole (BZ) and clomipramine (CLO), in mice infected with Trypanosoma cruzi, Casibla isolate which consists of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc1d5df3dd2fc3d9d3fd6269fb0e81b2
https://pubmed.ncbi.nlm.nih.gov/35060468

Analysis of mitochondrial enzymatic activity in blood lymphomonocyte fractions during infection with different Trypanosoma cruzi strains

Autor: Patricia A. Paglini-Oliva, Alejandra Baez, María Silvina Lo Presti, Daniela Alejandra Velázquez López, Noemí Miler, Héctor Walter Rivarola, Paola Carolina Bazán, Mariana Strauss

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Revista do Instituto de Medicina Tropical de São Paulo
Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020)
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e15
Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e15
Instituto de Medicina Tropical (IMT)
instacron:IMT
Revista do Instituto de Medicina Tropical de São Paulo, Volume: 62, Article number: e15, Published: 14 FEB 2020

Proinflammatory and inflammatory mediators induced by Trypanosoma cruzi infection increase the oxidative stress, generating toxicity for cells targeting mitochondria of different tissues. We studied the activity of citrate synthase and complexes I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe43e02ec1ec9745b466e45940ed5b1
https://www.scielo.br/j/rimtsp/a/Gy75fG8FKszV3Zz5V5TWFJv/?lang=en

Genomic medicine in Chagas disease

Autor: Javier Martín, Desiré Casares-Marfil, Mariana Strauss, Marialbert Acosta-Herrera

Genetic approaches have been proposed for improving the understanding of the causes of differential susceptibility to Trypanosoma cruzi infection and Chagas disease outcome. Polymorphisms in genes involved in the immune/inflammatory response are bein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fad91b2bf554acab6398a4fdc0d9c1
http://hdl.handle.net/10261/199174