Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mariana R. Brewer"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease characterized by intestinal inflammation and injury, with high mortality risk. Extracellular cold-inducible RNA-binding protein (eCIRP) is a recently discovered
Externí odkaz:
https://doaj.org/article/8ca4b251bfd5409a9a620bf2a94303bc
Autor:
Mabel N. Abraham, Ana Nedeljkovic-Kurepa, Tiago D. Fernandes, Omar Yaipen, Mariana R. Brewer, Daniel E. Leisman, Matthew D. Taylor, Clifford S. Deutschman
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Background The contribution of the central nervous system to sepsis pathobiology is incompletely understood. In previous studies, administration of endotoxin to mice decreased activity of the vagus anti-inflammatory reflex. Treatment with th
Externí odkaz:
https://doaj.org/article/1f6c39bde017455f943b50c9d73ef8c5
Autor:
Matthew D. Taylor, Mariana R. Brewer, Ana Nedeljkovic-Kurepa, Yihe Yang, Kalpana S. Reddy, Mabel N. Abraham, Betsy J. Barnes, Clifford S. Deutschman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent studies have demonstrated that induction of a diverse repertoire of memory T cells (“immune education”) affects responses to murine cecal ligation and puncture (CLP), the most widely – used animal model of sepsis. Among the documented ef
Externí odkaz:
https://doaj.org/article/01fef903f6ee4326b247f7f292b2aad9
Autor:
Chisom Egwuatu, Mariana R. Brewer, Regina Spinazzola, Vitaliya Boyar, Joanne Casatelli, Tesi Thomas, Elfriede Wallace, Barry Weinberger, Shahana Perveen
Publikováno v:
Journal of Neonatal Nursing. 29:459-463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5473d4365222fd7f1d6d3833ebf31c6
https://doi.org/10.1016/j.jnn.2022.09.003
https://doi.org/10.1016/j.jnn.2022.09.003
Autor:
Matthew D, Taylor, Tiago D, Fernandes, Omar, Yaipen, Cassidy E, Higgins, Christine A, Capone, Daniel E, Leisman, Ana, Nedeljkovic-Kurepa, Mabel N, Abraham, Mariana R, Brewer, Clifford S, Deutschman
Publikováno v:
Journal of Leukocyte Biology. 112:221-232
LPS challenge is used to model inflammation-induced organ dysfunction. The effects of T cell activation on LPS-mediated organ dysfunction and immune responses are unknown. We studied these interactions through in vivo administration of anti-CD3ε (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13ab77057e8f7aa6d1e80c58527a8b2
https://doi.org/10.1002/jlb.4hi0921-492r
https://doi.org/10.1002/jlb.4hi0921-492r
Autor:
Daniel E. Leisman, Jamie R. Privratsky, Jake R. Lehman, Mabel N. Abraham, Omar Y. Yaipan, Mariana R. Brewer, Ana Nedeljkovic-Kurepa, Christine C. Capone, Tiago D. Fernandes, Robert Griffiths, William J. Stein, Marcia B. Goldberg, Steven D. Crowley, Rinaldo Bellomo, Clifford S. Deutschman, Matthew D. Taylor
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Sepsis, defined as organ dysfunction caused by a dysregulated host-response to infection, is characterized by immunosuppression. The vasopressor norepinephrine is widely used to treat low blood pressure in sepsis but exacerbates immunosuppression. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619fb4fe3afdaa37368fa16517c73d42
https://doi.org/10.1073/pnas.2211370119
https://doi.org/10.1073/pnas.2211370119
Autor:
Ariel Brandwein, Daniel E. Leisman, Mariana R. Brewer, Tiago D. Fernandes, Matthew D. Taylor, Christine Capone, Mabel Abraham, Alexander P. Kelly, Clifford S. Deutschman
Publikováno v:
Shock
Outcomes variables for research on sepsis have centered on mortality and changes in the host immune response. However, a recent task force (Sepsis-3) revised the definition of sepsis to "life-threatening organ dysfunction caused by a dysregulated hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0fd7310a1fe44e2168c66b3314d0f7
https://europepmc.org/articles/PMC7987105/
https://europepmc.org/articles/PMC7987105/
Autor:
Joseph A. Asaro, Cynthia Pesce, Zarak Khan, Karen Klose, Champa N. Codipilly, Mariana R. Brewer, Richard J. Schanler
Publikováno v:
The Journal of pediatrics. 230
Objectives To investigate the relationships between dietary intake and fecal concentrations of milk fat globule-epidermal growth factor 8 (MFG-E8), and between fecal concentrations of MFG-E8 and markers of intestinal inflammation in infants born pret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd2009496562c9708719d6da488d9f2
https://pubmed.ncbi.nlm.nih.gov/33181195
https://pubmed.ncbi.nlm.nih.gov/33181195
Autor:
Joanne Casatelli, Barry Weinberger, Joanna Beachy, Elfriede Wallace, Shahana Perveen, Mariana R. Brewer, Jeong Eun Kim, Regina Spinazzola
Publikováno v:
Pediatric Quality & Safety
Introduction: Continuous positive airway pressure (CPAP) and surfactant both improve outcomes for premature infants with respiratory distress syndrome. However, prolonged trials of CPAP, as well as observation periods after intubation, may delay the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c295d15c24e5ab051c7d59f1b72d0ad
http://europepmc.org/articles/PMC7339153
http://europepmc.org/articles/PMC7339153