Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mariana Phillips"'
Autor:
Neha, Singh, Mariana, Phillips
Publikováno v:
Skin therapy letter. 27(5)
Toxic epidermal necrolysis (TEN) is an immune mediated, severe cutaneous adverse drug reaction characterized by epidermal detachment affecting greater than 30% body surface area. The mortality rate of TEN exceeds 20% and is usually caused by infectio
Publikováno v:
Dermatology Online Journal. 28
Targeted therapy (BRAF/MEK inhibitors) is frequently employed in the treatment of metastatic melanoma following immune checkpoint inhibitor therapy inefficacy or intolerance. Although BRAF inhibitors are commonly associated with cutaneous eruptions,
Publikováno v:
Skin therapy letter. 26(2)
Human papillomavirus (HPV)-induced cutaneous disease is a common complaint for patients presenting for dermatology evaluation. Infection by HPV is the major etiologic factor in the development of cutaneous warts, epidermodysplasia verruciformis, and
Publikováno v:
Skin therapy letter. 25(4)
Janus kinase inhibitors, also known as JAK inhibitors or jakinibs, represent a new class of medication that have broad potential to treat dermatologic disease. Currently, the only FDA-approved dermatologic indication for this class of medications is
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4019-4023
In the search for more potent peptide-based anti-cancer conjugates the generation of new, functionally diverse nucleolipid derived D-(KLAKLAK)2-AK sequences has enabled a structure and anti-cancer activity relationship study. A reductive amination ap
Publikováno v:
Biopolymers. 106:658-672
The rise of biologics that can stimulate immune responses towards the eradication of tumors has led to the evolution of cancer-based immunotherapy. Representatively, B7H6 has been recently identified as a protein ligand on tumor cells that binds spec
Publikováno v:
Dermatology online journal. 24(10)
The significance of basal cell carcinoma (BCC) invading the intravascular space is unknown. We report a case of an infiltrative BCC on the scalp that showed evidence of both intravascular and perineural invasion. The tumor locally recurred in the bon
Autor:
Megan L. Kelly, Brittany A. Blackman, Constantine Bitsaktsis, Ivonne Martinez, Stesha C. Joseph, Allan D. Blake, Mariana Phillips, David Sabatino, Michael W. Beaury, Christopher J. Parronchi
Publikováno v:
Journal of Peptide Science. 20:736-745
The solid-phase synthesis, structural characterization, and biological evaluation of a small library of cancer-targeting peptides have been determined in HepG2 hepatoblastoma cells. These peptides are based on the highly specific Pep42 motif, which h
Publikováno v:
Biopolymers. 106(5)
The rise of biologics that can stimulate immune responses towards the eradication of tumors has led to the evolution of cancer-based immunotherapy. Representatively, B7H6 has been recently identified as a protein ligand on tumor cells that binds spec
Publikováno v:
Peptides 2015, Proceedings of the 24th American Peptide Symposium.
Natural Killer (NK) cells are a class of cytotoxic lymphocytes with the ability to rapidly eliminate transformed or infected cells upon activation [1]. A key mediator of the NK cell line activity, NKp30, is a member of the natural cytotoxicity recept